PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

MYB

Protein Properties

Length: 331aa MW: 37201.5 Da PI: 6.1857

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00019.235	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	47.7	3.6e-15	14	62	1	48
TSSS-HHHHHHHHHHHHHTTTT.-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGgg.tWktIartmgkgRtlkqcksrwqkyl 48 +g+W++eEd +l+ ++q G+g +W + ++++g++R++k+c++rw++yl evm_27.model.AmTr_v1.0_scaffold00019.235 14 KGPWSPEEDAKLKAFIEQQGTGgNWIALPQKIGLKRCGKSCRLRWLNYL 62 79*********************************************97 PP
2	Myb_DNA-binding	37.2	7e-12	69	111	2	46
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 g +++eEd ++ + G++ W+ Ia+ ++ gRt++++k++w++ evm_27.model.AmTr_v1.0_scaffold00019.235 69 GGFSEEEDRIICSLYISIGSR-WSIIAAQLP-GRTDNDIKNYWNT 111 569****************.*****.*********97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	12.563	9	62	IPR017930	Myb domain
SuperFamily	SSF46689	7.52E-26	11	109	IPR009057	Homeodomain-like
SMART	SM00717	1.5E-11	13	64	IPR001005	SANT/Myb domain
Pfam	PF00249	7.7E-14	14	62	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.2E-23	15	69	IPR009057	Homeodomain-like
CDD	cd00167	5.71E-8	16	62	No hit	No description
PROSITE profile	PS51294	21.444	63	117	IPR017930	Myb domain
SMART	SM00717	3.3E-11	67	115	IPR001005	SANT/Myb domain
Pfam	PF00249	1.8E-10	69	111	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	8.8E-23	70	117	IPR009057	Homeodomain-like
CDD	cd00167	1.05E-7	71	113	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008285	Biological Process	negative regulation of cell proliferation
GO:0035987	Biological Process	endodermal cell differentiation
GO:0045597	Biological Process	positive regulation of cell differentiation
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:2000021	Biological Process	regulation of ion homeostasis
GO:2000067	Biological Process	regulation of root morphogenesis
GO:0048226	Cellular Component	Casparian strip
GO:0000975	Molecular Function	regulatory region DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 331 aa Download sequence Send to blast
MGRAPCCDKA NVKKGPWSPE EDAKLKAFIE QQGTGGNWIA LPQKIGLKRC GKSCRLRWLN 60 YLRPNIKHGG FSEEEDRIIC SLYISIGSRW SIIAAQLPGR TDNDIKNYWN TKLKKKLLGR 120 RKEQNSRRDS NADARNSPLM DSLSTSALER MQLHIQLQSL HHPLSLLSPS IWPRFPPLFD 180 GNSIENNKNT ARNFIPNDFA GNLIGKPPSN GKIGTETDER ENSTNGLSSP HSTRFNGDFI 240 SQEKPVANSG MSLEAIDGFL MEEGELQNGE TRGFLERETD RDGLDCFREM ESTSENLALW 300 VNDSESGSFN SWDTAYILGT EEYDLEHHLQ *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	8e-25	14	117	7	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factors that activates genes required for endodermal differentiation but represses genes involved in proliferative divisions, thus regulating the transition from proliferation to differentiation in root endodermis (PubMed:26371322). Required for Casparian strip formation by positively regulating the expression of the Casparian strip genes CASP1, PER64 and ESB1 and other endodermis-specific genes, thus triggering correct localized lignin biosynthesis in root endodermis and subsequently regulating global ion homeostasis (PubMed:26124109, PubMed:26371322). {ECO:0000269\|PubMed:26124109, ECO:0000269\|PubMed:26371322}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Directly up-regulated by SCARECROW (SCR), as part of the differentiation program controlled by SHORT-ROOT (SHR). {ECO:0000269\|PubMed:24517883, ECO:0000269\|PubMed:26371322}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006845592.1	0.0	transcription factor MYB36
Swissprot	Q9FKL2	5e-95	MYB36_ARATH; Transcription factor MYB36
TrEMBL	W1PBI8	0.0	W1PBI8_AMBTC; Uncharacterized protein
STRING	ERN07267	0.0	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP5	17	1784

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G57620.1	4e-81	myb domain protein 36

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00019.235
Entrez Gene	18435485

Publications ? help Back to Top
Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Fernández-Marcos M, et al. Control of Arabidopsis lateral root primordium boundaries by MYB36. New Phytol., 2017. 213(1): p. 105-112 [PMID:27891649]