PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

NAC

Protein Properties

Length: 178aa MW: 20078.9 Da PI: 10.1513

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00018.24	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	167.4	4.8e-52	9	140	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkky 68 lppGfrF Ptdeelv++yL++k++g + + +vi+evd++k+ePwdLp k +k+++ ew+fF++rd+ky evm_27.model.AmTr_v1.0_scaffold00018.24 9 LPPGFRFGPTDEELVSYYLRRKINGGRG-V-QVIPEVDMCKCEPWDLPgKsIIKNQDPEWFFFCPRDRKY 76 79*********************993.3.68***********6446677888******** PP NAM 69 atgkrknratksgyWkatgkdkevlsk....kgelvglkktLvfykgrapkgektdWvmheyrl 128 ++g+r+nratk+gyWkatg+d++++sk ++ l+g+kktLvf++grap+g+kt+W++heyr+ evm_27.model.AmTr_v1.0_scaffold00018.24 77 PNGRRSNRATKAGYWKATGNDRPIKSKshgsRSDLIGTKKTLVFHEGRAPHGKKTHWIVHEYRA 140 **********************987777777*************************96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	4.71E-54	3	145	IPR003441	NAC domain
PROSITE profile	PS51005	52.275	9	156	IPR003441	NAC domain
Pfam	PF02365	5.1E-28	10	139	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 178 aa Download sequence Send to blast
MAVMSLESLP PGFRFGPTDE ELVSYYLRRK INGGRGVQVI PEVDMCKCEP WDLPGKSIIK 60 NQDPEWFFFC PRDRKYPNGR RSNRATKAGY WKATGNDRPI KSKSHGSRSD LIGTKKTLVF 120 HEGRAPHGKK THWIVHEYRA NGNAFQDLNG SQFFLTVEVG VVNFGMLPVE IGNHASR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	9e-45	8	139	14	139	Stress-induced transcription factor NAC1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP) (PubMed:18443413, PubMed:24329768). Calmodulin-regulated transcriptional repressor. Binds several synthetic promoters with randomly selected binding sites (PubMed:17947243). Functions synergistically with SNI1 as negative regulator of pathogen-induced PR1 expression and basal resistance to a virulent strain of P.syringae. Binds directly to the promoter of the PR1 gene (PubMed:22826500). Acts as positive regulator of innate immunity. Involved in the effector-triggered immunity (ETI) induction of immunity-related gene expression (PubMed:24329768). Mediates osmotic stress signaling in leaf senescence by up-regulating senescence-associated genes (PubMed:18443413). {ECO:0000269\|PubMed:17947243, ECO:0000269\|PubMed:18443413, ECO:0000269\|PubMed:22826500, ECO:0000269\|PubMed:24329768}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011624192.1	1e-109	NAC domain-containing protein 62
Swissprot	F4JN35	6e-64	NTL9_ARATH; Protein NTM1-like 9
TrEMBL	W1PJE2	1e-130	W1PJE2_AMBTC; Uncharacterized protein
STRING	ERN08118	1e-131	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP17	15	800

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G35580.1	3e-66	NAC transcription factor-like 9

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00018.24

Publications ? help Back to Top
Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Zheng XY, et al. Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid. Proc. Natl. Acad. Sci. U.S.A., 2015. 112(30): p. 9166-73 [PMID:26139525] Guo T, et al. Lamin-like Proteins Negatively Regulate Plant Immunity through NAC WITH TRANSMEMBRANE MOTIF1-LIKE9 and NONEXPRESSOR OF PR GENES1 in Arabidopsis thaliana. Mol Plant, 2017. 10(10): p. 1334-1348 [PMID:28943325]