PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID evm_27.model.AmTr_v1.0_scaffold00010.297
Common NameAMTR_s00010p00239130, LOC18422350
Organism
Amborella trichopoda
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella
Family C2H2
Protein Properties Length: 437aa    MW: 50530.8 Da    PI: 6.8695
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00010.297genomeTAGPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.90.00067194216123
                                               EEETTTTEEESSHHHHHHHHHHT CS
                                   zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                                               y C+ C    +rk++L+rH+r++
  evm_27.model.AmTr_v1.0_scaffold00010.297 194 YFCEFCLNFMKRKEQLQRHMRKC 216
                                               78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541603.57E-2446161IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2702.8E-3650121No hitNo description
PfamPF117172.1E-2051109IPR025995RNA binding activity-knot of a chromodomain
SMARTSM002982.2E-565124IPR000953Chromo/chromo shadow domain
CDDcd000241.60E-665115No hitNo description
Gene3DG3DSA:2.30.30.2702.8E-36155205No hitNo description
PROSITE profilePS5172675.605160431IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557292.42E-111161432IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.304.3E-73219362IPR016181Acyl-CoA N-acyltransferase
PfamPF018533.0E-84221398IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00137272330No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010224Biological Processresponse to UV-B
GO:0016573Biological Processhistone acetylation
GO:2000028Biological Processregulation of photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0043995Molecular Functionhistone acetyltransferase activity (H4-K5 specific)
Sequence ? help Back to Top
Protein Sequence    Length: 437 aa     Download sequence    Send to blast
MGSLENTTEN GEPMDLPPCN GVGGGDSSFA LVETPPEKGL SRKIKPGILP LEVGTRVMCK  60
WRDNKYHSVK VIERRKLNNG GPNDYEYYVH YVEFNRRLDE WVKLEQLDLD SVEADVDEKV  120
EDKAASLKMT RHQKRKIDET HVEGHEELDA ASLREHEEFT KVKNIATIEL GRYEIETWYF  180
SPFPPEYSDS LKLYFCEFCL NFMKRKEQLQ RHMRKCDLKH PPGDEIYRSG TLSMFEVDGK  240
KNKVYTQNLC YLAKLFLDHK TLYYDVDLFL FYILCECDDR GCHMVGYFSK EKHSEESYNL  300
ACILTLPPYQ RKGYGKFLIA FSYELSKKEG KVGTPERPLS DLGLLSYRGY WTRVLLDILK  360
KHKSNISIKE LSDMTAIKAD DILSTLQNLE LIQYRKGQHA ICADPKVLDR HLKAAGRGGL  420
EVDVSKLIWT PYKEQS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1171564351282Histone acetyltransferase KAT8
4dnc_B1e-1171564351282Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006827084.10.0histone acetyltransferase of the MYST family 1
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLW1NFR60.0W1NFR6_AMBTC; Histone acetyltransferase
STRINGERM943210.0(Amborella trichopoda)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP389045
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Amborella Genome Project
    The Amborella genome and the evolution of flowering plants.
    Science, 2013. 342(6165): p. 1241089
    [PMID:24357323]
  5. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  6. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  7. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]