PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

ERF

Protein Properties

Length: 154aa MW: 17302.2 Da PI: 9.0167

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00009.86	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.7	1.5e-18	25	75	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 +y+GVr+++ +g+++AeIrd + + +r++lg+f taeeAa+a+++a+ +++g evm_27.model.AmTr_v1.0_scaffold00009.86 25 RYRGVRRRP-WGKYAAEIRDSTR---QgARVWLGTFYTAEEAARAYDRAAYAMRG 75 6******.******322...24***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	1.22E-16	24	84	No hit	No description
SuperFamily	SSF54171	4.51E-23	25	85	IPR016177	DNA-binding domain
SMART	SM00380	8.9E-34	25	89	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	9.4E-31	25	84	IPR001471	AP2/ERF domain
Pfam	PF00847	1.7E-13	25	75	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	23.472	25	83	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-11	26	37	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.7E-11	49	65	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 154 aa Download sequence Send to blast
MSPREGKSEE KGGEEKGGKE EEGARYRGVR RRPWGKYAAE IRDSTRQGAR VWLGTFYTAE 60 EAARAYDRAA YAMRGSLAIL NFPHEIPGRY VRSSSLSSSS SCSPRIGGGV DRERGNKRGE 120 SNCEKEVIVL EYLDDRYLDE LLESSEMREK RGR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	5e-31	22	85	11	74	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006827483.2	2e-51	ethylene-responsive transcription factor ERF094
Swissprot	A0A3Q7I5Y9	3e-36	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	W1NI59	1e-104	W1NI59_AMBTC; Uncharacterized protein
STRING	ERM94899	1e-105	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP6	16	1718

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23220.1	4e-22	ERF family protein

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00009.86
Entrez Gene	18422799

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]