PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

C2H2

Protein Properties

Length: 548aa MW: 59656.5 Da PI: 9.009

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_9.191	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.1	1.6e-05	6	28	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H evm.model.supercontig_9.191 6 FVCEICNKGFQRDQNLQLHRRGH 28 89*******************88 PP
2	zf-C2H2	15.5	5e-05	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ evm.model.supercontig_9.191 82 WKCDKCSKKYAVQSDWKAHQKTC 104 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	5.94E-8	5	28	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.8E-5	5	28	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SMART	SM00355	0.017	6	28	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	6	28	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	8	28	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	47	77	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	6.4E-5	70	103	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	5.94E-8	77	103	No hit	No description
SMART	SM00355	94	82	102	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 548 aa Download sequence Send to blast
MATNRFVCEI CNKGFQRDQN LQLHRRGHNL PWKLRQRTST EVKKRVYICP EPTCVHHNPA 60 RALGDLTGIK KHFSRKHGEK KWKCDKCSKK YAVQSDWKAH QKTCGTREYK CDCGTIFSRR 120 DSFITHRAFC DALAEENNKV NQGLMNQMGS NLQTQVPAEL MSSSMAGLNP NTINNPSIGS 180 DTFNTFDPKN PLKSLAQDLM PMPFKSMNMA GAGAGMFSSS SGTLFGGPRS NIASSSSSLQ 240 LSSNSTSSGF NYFHPDTKNG GSMSQLSAGS AHMSATALLQ KAAQMGATAS NSINSPMMQK 300 SFTGSMVGSD HNNHHHHHHQ IQGQLSSVRP SSSPAYSSAV QQHATNNSSS YDHIPPVMQN 360 HDDDRHHQSS HMVGINGGSS SSSTGLLPNQ LLRKNTQEIQ QIFDPSGNCS SAMNDIGILT 420 NMFMAGGEQN QGFPKNMEQE ESRSGSSLVQ GGRAALMADN RNNQIITGGS TRFGSGSSNG 480 GSSSDMMTLD FLGIGSVSRP VNLHEQQQKS LEMEAMSQQR LPLMNPYNQQ QLSHGDHSAI 540 EKPIWDV*

Sequence ? help Back to Top

Protein Sequence Length: 548 aa Download sequence Send to blast

MATNRFVCEI CNKGFQRDQN LQLHRRGHNL PWKLRQRTST EVKKRVYICP EPTCVHHNPA  60
RALGDLTGIK KHFSRKHGEK KWKCDKCSKK YAVQSDWKAH QKTCGTREYK CDCGTIFSRR  120
DSFITHRAFC DALAEENNKV NQGLMNQMGS NLQTQVPAEL MSSSMAGLNP NTINNPSIGS  180
DTFNTFDPKN PLKSLAQDLM PMPFKSMNMA GAGAGMFSSS SGTLFGGPRS NIASSSSSLQ  240
LSSNSTSSGF NYFHPDTKNG GSMSQLSAGS AHMSATALLQ KAAQMGATAS NSINSPMMQK  300
SFTGSMVGSD HNNHHHHHHQ IQGQLSSVRP SSSPAYSSAV QQHATNNSSS YDHIPPVMQN  360
HDDDRHHQSS HMVGINGGSS SSSTGLLPNQ LLRKNTQEIQ QIFDPSGNCS SAMNDIGILT  420
NMFMAGGEQN QGFPKNMEQE ESRSGSSLVQ GGRAALMADN RNNQIITGGS TRFGSGSSNG  480
GSSSDMMTLD FLGIGSVSRP VNLHEQQQKS LEMEAMSQQR LPLMNPYNQQ QLSHGDHSAI  540
EKPIWDV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-33	78	141	3	66	Zinc finger protein JACKDAW
5b3h_F	2e-33	78	141	3	66	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_9.191

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021906681.1	0.0	protein indeterminate-domain 9-like
Swissprot	Q9SCQ6	3e-98	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A3N7FC77	0.0	A0A3N7FC77_POPTR; Uncharacterized protein
STRING	evm.model.supercontig_9.191	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM15443	8	18
Representative plant	OGRP95	16	242

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	3e-82	indeterminate(ID)-domain 2

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_9.191

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]