PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

bHLH

Protein Properties

Length: 290aa MW: 31903.4 Da PI: 9.7004

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_55.142	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	25.9	1.8e-08	189	229	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L evm.model.supercontig_55.142 189 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 229 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	180	229	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.3E-14	181	238	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.44E-14	184	240	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.8E-14	186	235	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.0E-6	190	229	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.28E-6	203	234	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0048462	Biological Process	carpel formation
GO:0080126	Biological Process	ovary septum development
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 290 aa Download sequence Send to blast
MDVDMINSSP SSVAAEDHME IMTMMMQMEK LPEFCDLNFH ASNSSLHPEI QFSTSGNTLQ 60 QPIFQHPNTN INPTSCSSSS STSSMLINLP TSTSFMANPV PETSISTHHL HHPSVPTSGK 120 FRYGGLGPLF SNNANSYASS VEKKSSMAAM REMIFRIAAM QPIHIDPESI KPPKRRNVRI 180 SKDPQSVAAR HRRERISERI RILQRLVPGG TKMDTASMLD EAIHYVKFLK RQVQSLEQVA 240 ANRPMGSGLG LSGATLATNM GYSPLVKACQ PSNSAHYHHQ AMGNIQMLR*

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_55.142

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021897602.1	0.0	transcription factor HEC2
Swissprot	Q9SND4	4e-50	HEC2_ARATH; Transcription factor HEC2
TrEMBL	A0A0D2QX43	2e-88	A0A0D2QX43_GOSRA; Uncharacterized protein
TrEMBL	A0A1U8JWQ6	2e-88	A0A1U8JWQ6_GOSHI; transcription factor HEC2-like
STRING	evm.model.supercontig_55.142	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91
Representative plant	OGRP761	15	68

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G67060.1	9e-44	bHLH family protein

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_55.142

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231]