PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

ERF

Protein Properties

Length: 281aa MW: 31250.4 Da PI: 4.9188

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_51.136	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	57.6	3.2e-18	41	90	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++ GVr+++ +g+WvAeI+d + ++ r +lg+f taeeAa+a+++a+ l+g evm.model.supercontig_51.136 41 KFVGVRQRP-SGKWVAEIKDTT---QKIRMWLGTFETAEEAARAYDEAACLLRG 90 799****.7*****32...35********************99987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	19.533	41	98	IPR001471	AP2/ERF domain
SMART	SM00380	8.7E-36	41	104	IPR001471	AP2/ERF domain
CDD	cd00018	2.81E-32	41	97	No hit	No description
Pfam	PF00847	1.0E-12	41	90	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.8E-28	41	98	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.62E-19	41	98	IPR016177	DNA-binding domain
PRINTS	PR00367	4.8E-8	42	53	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.8E-8	64	80	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000302	Biological Process	response to reactive oxygen species
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009723	Biological Process	response to ethylene
GO:0035865	Biological Process	cellular response to potassium ion
GO:0048528	Biological Process	post-embryonic root development
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 281 aa Download sequence Send to blast
MEIHFQQQNQ YKRPSTSNPA AATKVNRSSC KSRNKANGTN KFVGVRQRPS GKWVAEIKDT 60 TQKIRMWLGT FETAEEAARA YDEAACLLRG SNTRTNFITH VSLDSPLAYR IRNLLNSKRG 120 GKQQQSVIDE DSPCSSNKTA TTTTTSPNID DPGSSSSSCS ENSPSGTDQT LQDSQLFDDA 180 YKPDLSNCRA EFQQMGSSQS DFSWGFDRFL CTQEVLELTN SGVLEEGSSN QEFSEFERMK 240 VERQISASLY AINGVQEYIE TVHDPNETLW DLPPLCSLFC *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	1e-14	40	107	13	81	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the symbiotic nodule signaling pathway in response to rhizobial stimulation. Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation, and nodule development. May coordinate these processes (PubMed:28503742, PubMed:28028038, PubMed:28068194). Functions downstream of the CCAMK-CYCLOPS complex (PubMed:28503742, PubMed:28028038). Probably not involved in arbuscular mycorrhizal (AM) symbiosis (PubMed:28068194). {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28068194, ECO:0000269\|PubMed:28503742}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00521	DAP	Transfer from AT5G19790	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_51.136

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in nodules 7 days after rhizobial inoculation. {ECO:0000269\|PubMed:28028038, ECO:0000269\|PubMed:28503742}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC237875	1e-35	AC237875.1 Solanum tuberosum cultivar RH89-039-16 clone RH168B16, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021898172.1	0.0	ethylene-responsive transcription factor RAP2-11
Swissprot	A0A1X9PY88	1e-103	ERN1_LOTJA; Ethylene-responsive transcription factor ERN1
TrEMBL	A0A438JL41	1e-107	A0A438JL41_VITVI; Ethylene-responsive transcription factor RAP2-11
TrEMBL	D7TI77	1e-107	D7TI77_VITVI; Uncharacterized protein
STRING	evm.model.supercontig_51.136	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7526	26	41
Representative plant	OGRP6	16	1718

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G19790.1	6e-41	related to AP2 11

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_51.136

Publications ? help Back to Top
Yano K, et al. Function and evolution of a Lotus japonicus AP2/ERF family transcription factor that is required for development of infection threads. DNA Res., 2017. 24(2): p. 193-203 [PMID:28028038] Kawaharada Y,James EK,Kelly S,Sandal N,Stougaard J The Ethylene Responsive Factor Required for Nodulation 1 (ERN1) Transcription Factor Is Required for Infection-Thread Formation in Lotus japonicus. Mol. Plant Microbe Interact., 2017. 30(3): p. 194-204 [PMID:28068194] Cerri MR, et al. The ERN1 transcription factor gene is a target of the CCaMK/CYCLOPS complex and controls rhizobial infection in Lotus japonicus. New Phytol., 2017. 215(1): p. 323-337 [PMID:28503742]