PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

MIKC_MADS

Protein Properties

Length: 229aa MW: 26428.9 Da PI: 9.5911

Description

MIKC_MADS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_50.73	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	SRF-TF	99.5	1.4e-31	9	58	1	50
S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE CS SRF-TF 1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeys 50 krien++nrqvtf+kRrng+lKKA+ELSvLCdaeva+i+fss+g+lyey+ evm.model.supercontig_50.73 9 KRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYA 58 79***********************************************8 PP
2	K-box	116.6	2.2e-38	79	173	6	100
K-box 6 gksleeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekel 87 s++ea+++ +qqe++kL+++i+++q+++Rh+lGe L+sL++keL++Le +Lek++++iRskKnell+++ie++qk+e el evm.model.supercontig_50.73 79 PGSVTEANTQFYQQEATKLRRQIREIQNSNRHILGEALGSLTFKELKNLEGRLEKGISRIRSKKNELLFAEIEYMQKREIEL 160 34599*************************************************************************** PP K-box 88 qeenkaLrkklee 100 q++n++Lr+k++e evm.model.supercontig_50.73 161 QNDNMYLRAKIAE 173 ********986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00432	6.9E-42	1	60	IPR002100	Transcription factor, MADS-box
PROSITE profile	PS50066	33.599	1	61	IPR002100	Transcription factor, MADS-box
CDD	cd00265	2.87E-44	2	75	No hit	No description
SuperFamily	SSF55455	9.16E-33	3	73	IPR002100	Transcription factor, MADS-box
PROSITE pattern	PS00350	0	3	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.8E-33	3	23	IPR002100	Transcription factor, MADS-box
Pfam	PF00319	8.1E-27	10	57	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.8E-33	23	38	IPR002100	Transcription factor, MADS-box
PRINTS	PR00404	3.8E-33	38	59	IPR002100	Transcription factor, MADS-box
Pfam	PF01486	2.4E-28	85	171	IPR002487	Transcription factor, K-box
PROSITE profile	PS51297	15.558	87	177	IPR002487	Transcription factor, K-box

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0048481	Biological Process	plant ovule development
GO:0090376	Biological Process	seed trichome differentiation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 229 aa Download sequence Send to blast
MARGKIEIKR IENTTNRQVT FCKRRNGLLK KAYELSVLCD AEVALIVFSS RGRLYEYANN 60 SVKATIERYK KACSDATNPG SVTEANTQFY QQEATKLRRQ IREIQNSNRH ILGEALGSLT 120 FKELKNLEGR LEKGISRIRS KKNELLFAEI EYMQKREIEL QNDNMYLRAK IAENERVQEQ 180 QQSNLMQGSV YESMPSQSQT YNRNFLPVNL LEPNHQYSAD DHTALQLV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1tqe_P	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
1tqe_Q	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
1tqe_R	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
1tqe_S	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
6c9l_A	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
6c9l_B	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
6c9l_C	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
6c9l_D	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
6c9l_E	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
6c9l_F	2e-20	1	69	1	69	Myocyte-specific enhancer factor 2B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Interacts genetically with TT16/AGL32 in a partially antagonistic manner during flower development. Is essential for the coordination of cell divisions in ovule, seed coat development and endosperm formation (PubMed:27776173). {ECO:0000269\|PubMed:27776173}.
UniProt	Probable transcription factor involved in flower development. {ECO:0000250\|UniProtKB:Q0HA25}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00093	SELEX	Transfer from AT3G58780	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_50.73

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021898389.1	1e-168	agamous-like MADS-box protein AGL1 isoform X2
Swissprot	P29381	1e-133	AGL1_ARATH; Agamous-like MADS-box protein AGL1
Swissprot	Q93XH4	1e-133	MADS1_VITVI; Agamous-like MADS-box protein MADS1
TrEMBL	A6YRN8	1e-166	A6YRN8_CARPA; C-class floral identity
STRING	evm.model.supercontig_50.73	1e-167	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3341	23	50
Representative plant	OGRP16	17	761

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G58780.1	1e-135	MIKC_MADS family protein

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_50.73

Publications ? help Back to Top
Boss PK,Vivier M,Matsumoto S,Dry IB,Thomas MR A cDNA from grapevine (Vitis vinifera L.), which shows homology to AGAMOUS and SHATTERPROOF, is not only expressed in flowers but also throughout berry development. Plant Mol. Biol., 2001. 45(5): p. 541-53 [PMID:11414613] Jaillon O, et al. The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla. Nature, 2007. 449(7161): p. 463-7 [PMID:17721507] Díaz-Riquelme J,Lijavetzky D,Martínez-Zapater JM,Carmona MJ Genome-wide analysis of MIKCC-type MADS box genes in grapevine. Plant Physiol., 2009. 149(1): p. 354-69 [PMID:18997115] Grimplet J,Martínez-Zapater JM,Carmona MJ Structural and functional annotation of the MADS-box transcription factor family in grapevine. BMC Genomics, 2016. 17: p. 80 [PMID:26818751] Matalon O, et al. Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity. Sci Signal, 2016. 9(429): p. ra54 [PMID:27221712] Ehlers K, et al. The MADS Box Genes ABS, SHP1, and SHP2 Are Essential for the Coordination of Cell Divisions in Ovule and Seed Coat Development and for Endosperm Formation in Arabidopsis thaliana. PLoS ONE, 2016. 11(10): p. e0165075 [PMID:27776173]