PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

MYB

Protein Properties

Length: 564aa MW: 61912.4 Da PI: 8.3847

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_228.17	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	51	3.2e-16	59	105	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g WT++Ede l +av+ + g++Wk+Ia+ ++ R++ qc +rwqk+l evm.model.supercontig_228.17 59 KGGWTPQEDETLRNAVAAFKGKSWKKIAEFFP-DRSEVQCLHRWQKVL 105 688***************************.**********986 PP
2	Myb_DNA-binding	60.9	2.6e-19	111	157	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEd++++++v+++G+ W+ Ia+ ++ gR +kqc++rw+++l evm.model.supercontig_228.17 111 KGPWTQEEDDKIIELVARYGPTKWSVIAKSLP-GRIGKQCRERWHNHL 157 79****************************.***********97 PP
3	Myb_DNA-binding	53.2	6.6e-17	163	206	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +++WT +E++ l +a++ +G++ W+ Ia+ ++ gRt++++k++w++ evm.model.supercontig_228.17 163 KDAWTLDEELALMNAHRVHGNK-WAEIAKVLP-GRTDNSIKNHWNS 206 679*****************.*****.*********96 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	14.982	54	105	IPR017930	Myb domain
SMART	SM00717	5.3E-14	58	107	IPR001005	SANT/Myb domain
Pfam	PF00249	5.9E-15	59	105	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	7.18E-15	60	115	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.4E-18	61	111	IPR009057	Homeodomain-like
CDD	cd00167	3.66E-12	62	105	No hit	No description
PROSITE profile	PS51294	32.175	106	161	IPR017930	Myb domain
SuperFamily	SSF46689	3.41E-31	108	204	IPR009057	Homeodomain-like
SMART	SM00717	4.1E-18	110	159	IPR001005	SANT/Myb domain
Pfam	PF00249	9.0E-19	111	157	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.2E-27	112	160	IPR009057	Homeodomain-like
CDD	cd00167	5.82E-16	113	157	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.9E-23	161	212	IPR009057	Homeodomain-like
SMART	SM00717	1.3E-15	162	210	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	22.073	162	212	IPR017930	Myb domain
Pfam	PF00249	3.6E-15	163	206	IPR001005	SANT/Myb domain
CDD	cd00167	7.66E-12	165	208	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 564 aa Download sequence Send to blast
MAELKVEECC LENKQLTTAS SSSISEGSGS AILKSPAISS PAATSPTHRR TTGPIRRAKG 60 GWTPQEDETL RNAVAAFKGK SWKKIAEFFP DRSEVQCLHR WQKVLNPDLV KGPWTQEEDD 120 KIIELVARYG PTKWSVIAKS LPGRIGKQCR ERWHNHLNPD IKKDAWTLDE ELALMNAHRV 180 HGNKWAEIAK VLPGRTDNSI KNHWNSSLKK KLDFYLATGK LPPVAKNGLQ NGTKDTNRST 240 VTKKLLASSN KDSDSAAQTS SGTTDICKLD EDGKDHIDSL APKQDAAVSS SGLPNESGDS 300 ENVECRPQLS NAGTTCSNLE SVPKFENHGT SSEIVEDTDT GRQLQFGTPT YGSLYYEPPQ 360 FENCIPSDID LFCTCGVSHD CSSGPNISPI CFFTPPCVKD SARGMQSPES ILKIAAKTFP 420 NTPSIFRKRK IVSQGHQIIN KVEKVDAEMV KGRPHASNKH ERAENSSEKS LFENESLCSS 480 PAFRENDVAG PTSKAFNVSP PYRLRSKRTA VFKSVERQLE FSSKKEKSDV NIRSSDLSVN 540 RSSAVSEDCS HTTKLGSDLG HKL*

Sequence ? help Back to Top

Protein Sequence Length: 564 aa Download sequence Send to blast

MAELKVEECC LENKQLTTAS SSSISEGSGS AILKSPAISS PAATSPTHRR TTGPIRRAKG  60
GWTPQEDETL RNAVAAFKGK SWKKIAEFFP DRSEVQCLHR WQKVLNPDLV KGPWTQEEDD  120
KIIELVARYG PTKWSVIAKS LPGRIGKQCR ERWHNHLNPD IKKDAWTLDE ELALMNAHRV  180
HGNKWAEIAK VLPGRTDNSI KNHWNSSLKK KLDFYLATGK LPPVAKNGLQ NGTKDTNRST  240
VTKKLLASSN KDSDSAAQTS SGTTDICKLD EDGKDHIDSL APKQDAAVSS SGLPNESGDS  300
ENVECRPQLS NAGTTCSNLE SVPKFENHGT SSEIVEDTDT GRQLQFGTPT YGSLYYEPPQ  360
FENCIPSDID LFCTCGVSHD CSSGPNISPI CFFTPPCVKD SARGMQSPES ILKIAAKTFP  420
NTPSIFRKRK IVSQGHQIIN KVEKVDAEMV KGRPHASNKH ERAENSSEKS LFENESLCSS  480
PAFRENDVAG PTSKAFNVSP PYRLRSKRTA VFKSVERQLE FSSKKEKSDV NIRSSDLSVN  540
RSSAVSEDCS HTTKLGSDLG HKL*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	2e-67	58	212	5	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	2e-67	58	212	5	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (By similarity). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). {ECO:0000250\|UniProtKB:Q94FL9, ECO:0000269\|PubMed:26069325}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00482	DAP	Transfer from AT5G02320	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_228.17

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by ethylene and salicylic acid (SA). {ECO:0000269\|PubMed:16463103}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021886823.1	0.0	transcription factor MYB3R-3 isoform X1
Swissprot	Q6R032	1e-180	MB3R5_ARATH; Transcription factor MYB3R-5
TrEMBL	A0A4D6V172	0.0	A0A4D6V172_9ROSI; MYB transcription factor 33
STRING	evm.model.supercontig_228.17	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1667	28	87
Representative plant	OGRP5	17	1784

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02320.2	1e-169	myb domain protein 3r-5

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_228.17

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]