PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

C2H2

Protein Properties

Length: 151aa MW: 16842.3 Da PI: 10.9816

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_216.26	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.4	6.1e-06	82	104	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 + C++C+k F r nL+ H r H evm.model.supercontig_216.26 82 FICEICNKGFQRDQNLQLHRRGH 104 89*******************88 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.75E-5	80	105	No hit	No description
Gene3D	G3DSA:3.30.160.60	2.6E-6	81	104	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12171	1.2E-5	82	104	IPR022755	Zinc finger, double-stranded RNA binding
PROSITE profile	PS50157	10.845	82	104	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	84	104	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 151 aa Download sequence Send to blast
MMHQNHVHGL SVSSTVKGFV PPPPHRHQQT ATSNPNPNPN PNNNPSANPA ANKKKRNLPG 60 TPDPDAEVIA LSPKSLMATN RFICEICNKG FQRDQNLQLH RRGHNLPWKL RQRTNKEVVR 120 KKVYICPEKS CVHHDPSRAL GDLTGIKKHL *

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	108	121	KLRQRTNKEVVRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_216.26

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021887023.1	1e-105	LOW QUALITY PROTEIN: protein indeterminate-domain 9
Swissprot	Q9SCQ6	2e-60	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A059ABD4	2e-67	A0A059ABD4_EUCGR; Uncharacterized protein
TrEMBL	A0A3N6U000	1e-67	A0A3N6U000_BRACR; Uncharacterized protein
STRING	evm.model.supercontig_216.26	1e-107	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP95	16	242

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G45260.1	1e-61	C2H2-like zinc finger protein

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_216.26

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]