PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

Dof

Protein Properties

Length: 333aa MW: 35387.5 Da PI: 9.0247

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.model.supercontig_188.14	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	123.8	5.7e-39	79	138	3	62
zf-Dof 3 ekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 e+alkcprC+stntkfCy+nnyslsqPr+fCk+CrryWt+GGalrnvPvGgg+r+nk+s+ evm.model.supercontig_188.14 79 ETALKCPRCESTNTKFCYFNNYSLSQPRHFCKTCRRYWTRGGALRNVPVGGGCRRNKRSK 138 7789*****************************************************975 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	5.0E-34	62	131	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	1.0E-32	81	136	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	29.609	82	136	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	84	120	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 333 aa Download sequence Send to blast
MVFTSIPAYL DPVNWQQQQV ANHQAGGTSG AGIHLLPPPP PPPPLPPAVP QPHGEGGAGS 60 IRPGSMADRA RLANIPMPET ALKCPRCEST NTKFCYFNNY SLSQPRHFCK TCRRYWTRGG 120 ALRNVPVGGG CRRNKRSKGS NSSKSSSAVS GDRPTGSGST ASMSCNSNEM IGLGTPLPQL 180 RFMAPLHHLT GHDDLGLSYG PVSAPLVGGT SELVPGTSLL LDQWRLQQFP LLGGFDSSYG 240 LYPFEASSYG GGAGQIRPKL STTGMATQLA SVKMEDSNNN NNSNQQEMNL SRQFLGVNPA 300 AGYDHIHHYW NNAATSWSDV SSFSSSSTSN PL*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Binds to 5'-TAAAGT-3' motif in REV promoter to triggers its transcription, thus regulating adaxial-abaxial polarity and influencing leaf axial patterning in an auxin transport- and response-dependent manner (e.g. IAA6 and IAA19 genes expression) (PubMed:20807212). Probably involved in early processes for vascular development (PubMed:17583520). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). {ECO:0000250\|UniProtKB:Q9M2U1, ECO:0000269\|PubMed:17583520, ECO:0000269\|PubMed:20807212, ECO:0000269\|PubMed:30626969}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00483	DAP	Transfer from AT5G02460	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.model.supercontig_188.14

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cytokinin in procambium. {ECO:0000269\|PubMed:30626969}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021887727.1	0.0	dof zinc finger protein DOF5.1-like
Swissprot	Q9LZ56	2e-57	DOF51_ARATH; Dof zinc finger protein DOF5.1
TrEMBL	A0A061ET14	1e-118	A0A061ET14_THECC; DNA binding with one finger 2.4, putative
STRING	evm.model.supercontig_188.14	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1713	28	86
Representative plant	OGRP38	17	445

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G37590.1	5e-49	DNA binding with one finger 2.4

Link Out ? help Back to Top
Phytozome	evm.model.supercontig_188.14

Publications ? help Back to Top
Miyashima S, et al. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature, 2019. 565(7740): p. 490-494 [PMID:30626969]