PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | evm.model.supercontig_104.59 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica
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Family | E2F/DP | ||||||||
Protein Properties | Length: 489aa MW: 53279.3 Da PI: 6.1909 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86 | 2.8e-27 | 215 | 280 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg evm.model.supercontig_104.59 215 RYDSSLGLLTKKFINLVKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 280 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 2.2E-29 | 212 | 282 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 6.8E-17 | 215 | 278 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 9.9E-35 | 215 | 280 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.4E-24 | 217 | 280 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 4.71E-13 | 295 | 346 | No hit | No description |
Pfam | PF16421 | 2.9E-15 | 295 | 344 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 489 aa Download sequence Send to blast |
MSSGARASSR PHPPPHPPSS SAAPAAATVV PPIRRHLAFA STKPPFVPPN DYHRFSPSPA 60 SNNNNICSMN TRRVVDREAD AVVFRSPVEC FLDLLLLWFC LDQRDGFIVI LSVFGYWNLC 120 PIRFYLVLVS NFIPPIIWHL QIKRKTATSE NEVEASGCAS PGLTNISNSP FKTPVATKGR 180 ANNRSRASKS NRSAPQTPVS NAGSPAPLTP AGSCRYDSSL GLLTKKFINL VKHAEDGILD 240 LNKAAETLEV QKRRIYDITN VLEGIGLIEK KLKNRIRWKG LDAAKPGEVD GDACILQNET 300 LIAIKAPHGT TLEVPDPDEA VDYPQRRYRI ILRSTMGPID VYLVSQFEEK FEEMNGMEPR 360 ASCQLASSSG SNENQVMEML TLDSPGKELD AQASQTQPMC SDINASQEFA GGIMKITPSD 420 VDNDADYWLL SEADVSITNM WKTDSGMEWA GVNVLSDFGL ADVSSPRPQT PPNATVEVPS 480 ATLNSSAR* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 5e-24 | 210 | 281 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00293 | DAP | Transfer from AT2G36010 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | evm.model.supercontig_104.59 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_021892443.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-140 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A2P5Y1W5 | 0.0 | A0A2P5Y1W5_GOSBA; Uncharacterized protein | ||||
STRING | evm.model.supercontig_104.59 | 0.0 | (Carica papaya) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 | Representative plant | OGRP1225 | 17 | 49 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.2 | 1e-121 | E2F transcription factor 3 |
Link Out ? help Back to Top | |
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Phytozome | evm.model.supercontig_104.59 |
Publications ? help Back to Top | |||
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