PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica

Family

C2H2

Protein Properties

Length: 481aa MW: 52843.9 Da PI: 6.9337

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm.TU.contig_27573.2	genome	ASGPB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	11.4	0.001	127	149	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp Cg s+++ ++ H ++ evm.TU.contig_27573.2 127 FECPVCGISYRSEEEVSAHVESC 149 89*****************8776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd09212	8.49E-20	179	274	No hit	No description
SuperFamily	SSF143503	5.49E-18	192	259	IPR018997	PUB domain
SMART	SM00580	6.0E-17	192	253	IPR018997	PUB domain
Pfam	PF09409	2.0E-16	193	255	IPR018997	PUB domain
SuperFamily	SSF54236	3.36E-12	341	453	IPR029071	Ubiquitin-related domain
Gene3D	G3DSA:3.10.20.90	1.7E-7	368	452	No hit	No description
PROSITE profile	PS50033	11.171	369	453	IPR001012	UBX domain
Pfam	PF00789	3.8E-5	369	425	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 481 aa Download sequence Send to blast
MDDMKDKVKG FMKKVNNPFT SSSSGKFKGQ SRVLGSASSG PVNPIPARYS HPQTHAPQRN 60 PSSSSSSSVA PTNSKPLPQK PLNSDQNKHS STNSPDPDRK PANGFDPYDS LITSGKRSQN 120 GYSLNVFECP VCGISYRSEE EVSAHVESCL NSNSADKNGD ADVSRLADDG SETKTEVEAC 180 VRAFLSGNPP EGSVDVILRL LRNIVKEPEN PKFRKIRMSN PKIREAIGEV GGAVELLEFL 240 GFELKEEGGE ICSMMGAPSE KGISLISKAI ALLEPRKTEE EPKKTENFKS ATPANSEEVV 300 QLKKANRQIR IFFSVPESVA AKIELPDSFY NLSAEELKRE ADTRKKKIAE SQLLIPKSYK 360 EKQAKAARKR YTKTVIRVQF PDGVVLQGIF FPWEPTSALY EFVSSALKEP GLEFELLDPV 420 LVRRKVIPSF PAPGEKARTL DDEDLVPSAL IKFRPIESDS ILFTGLSNEL LEIIEPLDSA 480 A

Sequence ? help Back to Top

Protein Sequence Length: 481 aa Download sequence Send to blast

MDDMKDKVKG FMKKVNNPFT SSSSGKFKGQ SRVLGSASSG PVNPIPARYS HPQTHAPQRN  60
PSSSSSSSVA PTNSKPLPQK PLNSDQNKHS STNSPDPDRK PANGFDPYDS LITSGKRSQN  120
GYSLNVFECP VCGISYRSEE EVSAHVESCL NSNSADKNGD ADVSRLADDG SETKTEVEAC  180
VRAFLSGNPP EGSVDVILRL LRNIVKEPEN PKFRKIRMSN PKIREAIGEV GGAVELLEFL  240
GFELKEEGGE ICSMMGAPSE KGISLISKAI ALLEPRKTEE EPKKTENFKS ATPANSEEVV  300
QLKKANRQIR IFFSVPESVA AKIELPDSFY NLSAEELKRE ADTRKKKIAE SQLLIPKSYK  360
EKQAKAARKR YTKTVIRVQF PDGVVLQGIF FPWEPTSALY EFVSSALKEP GLEFELLDPV  420
LVRRKVIPSF PAPGEKARTL DDEDLVPSAL IKFRPIESDS ILFTGLSNEL LEIIEPLDSA  480
A

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	2e-13	320	453	19	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	evm.TU.contig_27573.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021898429.1	0.0	plant UBX domain-containing protein 2
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	A0A1R3JGP2	0.0	A0A1R3JGP2_9ROSI; Uncharacterized protein
STRING	evm.TU.contig_27573.2	0.0	(Carica papaya)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9835	16	18
Representative plant	OGRP6047	2	3

Link Out ? help Back to Top
Phytozome	evm.TU.contig_27573.2

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]