PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_9367_iso_3
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family bHLH
Protein Properties Length: 490aa    MW: 54110.7 Da    PI: 5.5678
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_9367_iso_3genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH407.2e-13342388455
                                          HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                                  HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                                          +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  cra_locus_9367_iso_3_len_2273_ver_3 342 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITDLQ 388
                                          799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142152.5E-4449229IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.806338387IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000835.59E-14341392No hitNo description
SuperFamilySSF474591.96E-17341399IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.105.9E-17342400IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.4E-10342388IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.8E-16344393IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 490 aa     Download sequence    Send to blast
MGDNFWLNKE DKALVELVLG SEAVEFFIWL ATNNILSEFT PPGGDLRVQE GLSRLVEGSN  60
WTYAIYWHVS TSKSGKSALI WGDGHCREPK TSEKQAENGD KDKRSLEGDR RRQALQKIHS  120
CFGGAEDDNI AAKLDSVSEV EIFYLTSMYL AFPFDKPSIP SQAFNTSRSI WTSDSKSSLE  180
NYQSRAVLAK SAHLETVVFI PLKSGVVEIG SVKSLPEDPN LIQTVKTTFA AAVAQSRTLP  240
KIFGQELSLG GTKPGPISIS FSPKVEDDSA FTADSYELQA LGGQVYGPSN GIDEGEKLFP  300
VRNQSVLSSL EQARDDSLIQ SDERKPRKRG RKPANGRDEP LNHVEAERQR REKLNQRFYA  360
LRAVVPNISK MDKASLLGDA IAYITDLQKK IRTIEGEKET SGDNNKPKNI DIQDIDFHER  420
QEDAIVQVSC PLDAHPVSQV VKALREHQVV AQESNVSLTE NGDVVHAFSI QTPGGAAEQL  480
KEKLAATLLK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A6e-29336398264Transcription factor MYC2
5gnj_B6e-29336398264Transcription factor MYC2
5gnj_E6e-29336398264Transcription factor MYC2
5gnj_F6e-29336398264Transcription factor MYC2
5gnj_G6e-29336398264Transcription factor MYC2
5gnj_I6e-29336398264Transcription factor MYC2
5gnj_M6e-29336398264Transcription factor MYC2
5gnj_N6e-29336398264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1323331RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00099PBMTransfer from AT4G16430Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027160198.10.0transcription factor bHLH3
RefseqXP_027160207.10.0transcription factor bHLH3
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A2U9IY190.0A0A2U9IY19_CATRO; Jasmonate-associated MYC2-like 3
STRINGMigut.D00401.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA66692433
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]