PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Protein Features |

3D Structure |

Function |

Orthologous Group |

Publication

Basic Information? help Back to Top

TF ID

cra_locus_8986_iso_3

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

GRAS

Protein Properties

Length: 374aa MW: 42720.2 Da PI: 5.8797

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_8986_iso_3	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	247.6	4.8e-76	28	314	3	292
GRAS 3 elLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykalppsetseknsse 76 +lL ecA a+s++d +++++l + l+elasp+gd q+la+yf++A + ++s++++yk+l++ ++++++ ++ cra_locus_8986_iso_3_len_1118_ver_3 28 RLLRECAVAISEKDSNKIHHLFWMLNELASPYGDCDQKLASYFLQAFFCKTTESGQRCYKILASVAEKSHSFDS 101 6899********************************************************999998666555 PP GRAS 77 elaalklfsevsPilkfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgsp 150 + + f+evsP+ +f+h + N aIlea+ege+++HiiD++ + ++QWp+Ll+aLa R++++p+l++T+v + cra_locus_8986_iso_3_len_1118_ver_3 102 AKKLILKFQEVSPWTTFGHAASNGAILEALEGENKLHIIDISNTLCTQWPTLLEALAIRNDETPHLKLTVVIAT 175 5555556**************************************************************8 PP GRAS 151 esgskeeleetgerLakfAeelgvpfefnvl.vakrledleleeLrvkpgEalaVnlvlqlhrlldesvslese 223 + +++ ++e+ +r++kfA+ +gvpfefnv+ ++l +l+ e+L+++++Ea+a+n++ +l r+ +e+ cra_locus_8986_iso_3_len_1118_ver_3 176 NIVKSSIMKEISQRMKKFARLMGVPFEFNVIsGLNHLGELTKESLNIQNDEAIAINCIGALRRIQ-----VEE- 243 988***********************955679************************7.....444. PP GRAS 224 rdevLklvkslsPkvvvvveqeadh.nse.sFlerflealeyysalfdsleaklpreseerikvErellgr 292 r++++k++ sl+P+vv++ve+ead ns +F++ f e+l++ + f++le+++p++s+er ++Ere+ +r cra_locus_8986_iso_3_len_1118_ver_3 244 RSDMIKMLLSLNPRVVTIVEEEADFsNSRiDFVKCFEECLRFTTLYFEMLEESFPPTSNERLMLEREYGQR 314 779*****************9655469*********************************98655 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50985	38.686	1	374	IPR005202	Transcription factor GRAS
Pfam	PF03514	1.7E-73	28	314	IPR005202	Transcription factor GRAS

Sequence ? help Back to Top
Protein Sequence Length: 374 aa Download sequence Send to blast
XTSTSKSTDY GEPTRDDSDG GRKQWAPRLL RECAVAISEK DSNKIHHLFW MLNELASPYG 60 DCDQKLASYF LQAFFCKTTE SGQRCYKILA SVAEKSHSFD SAKKLILKFQ EVSPWTTFGH 120 AASNGAILEA LEGENKLHII DISNTLCTQW PTLLEALAIR NDETPHLKLT VVIATNIVKS 180 SIMKEISQRM KKFARLMGVP FEFNVISGLN HLGELTKESL NIQNDEAIAI NCIGALRRIQ 240 VEERSDMIKM LLSLNPRVVT IVEEEADFSN SRIDFVKCFE ECLRFTTLYF EMLEESFPPT 300 SNERLMLERE YGQRGFEKPL HRSDXSDDIV DDVKALLKRY RSGWSLRLPQ SDHESGIYLT 360 WKEDPVVWAS AWKP

Sequence ? help Back to Top

Protein Sequence Length: 374 aa Download sequence Send to blast

XTSTSKSTDY GEPTRDDSDG GRKQWAPRLL RECAVAISEK DSNKIHHLFW MLNELASPYG  60
DCDQKLASYF LQAFFCKTTE SGQRCYKILA SVAEKSHSFD SAKKLILKFQ EVSPWTTFGH  120
AASNGAILEA LEGENKLHII DISNTLCTQW PTLLEALAIR NDETPHLKLT VVIATNIVKS  180
SIMKEISQRM KKFARLMGVP FEFNVISGLN HLGELTKESL NIQNDEAIAI NCIGALRRIQ  240
VEERSDMIKM LLSLNPRVVT IVEEEADFSN SRIDFVKCFE ECLRFTTLYF EMLEESFPPT  300
SNERLMLERE YGQRGFEKPL HRSDXSDDIV DDVKALLKRY RSGWSLRLPQ SDHESGIYLT  360
WKEDPVVWAS AWKP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_B	1e-124	24	374	31	420	Protein SHORT-ROOT
5b3h_E	1e-124	24	374	31	420	Protein SHORT-ROOT
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for both cell division and cell specification. Regulates the radial organization of the shoot axial organs and is required for normal shoot gravitropism. Directly controls the transcription of SCR, and when associated with SCR, of MGP, RLK, TRI, NUC and SCL3. {ECO:0000269\|PubMed:10850497, ECO:0000269\|PubMed:12569126, ECO:0000269\|PubMed:15314023, ECO:0000269\|PubMed:16640459, ECO:0000269\|PubMed:17446396, ECO:0000269\|PubMed:9670559}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027117536.1	0.0	protein SHORT-ROOT-like
Swissprot	Q9SZF7	1e-123	SHR_ARATH; Protein SHORT-ROOT
TrEMBL	A0A068U5L3	0.0	A0A068U5L3_COFCA; Uncharacterized protein
STRING	POPTR_0017s05450.1	0.0	(Populus trichocarpa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2031	24	64

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Muraro D, et al. Integration of hormonal signaling networks and mobile microRNAs is required for vascular patterning in Arabidopsis roots. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(2): p. 857-62 [PMID:24381155] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Gao X,Wang C,Cui H Identification of bundle sheath cell fate factors provides new tools for C3-to-C4 engineering. Plant Signal Behav, 2018. [PMID:24819776] Ahrazem O, et al. Ectopic expression of a stress-inducible glycosyltransferase from saffron enhances salt and oxidative stress tolerance in Arabidopsis while alters anchor root formation. Plant Sci., 2015. 234: p. 60-73 [PMID:25804810] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Miguel A,Milhinhos A,Novák O,Jones B,Miguel CM The SHORT-ROOT-like gene PtSHR2B is involved in Populus phellogen activity. J. Exp. Bot., 2016. 67(5): p. 1545-55 [PMID:26709311] Gong X, et al. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol., 2016. 170(3): p. 1675-83 [PMID:26818732] Kim ES, et al. HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots. Physiol Plant, 2016. 157(2): p. 221-33 [PMID:26968317] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Li Q,Zhao Y,Yue M,Xue Y,Bao S The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage. J Genet Genomics, 2016. 43(4): p. 187-97 [PMID:27090604] Clark NM, et al. Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. Elife, 2017. [PMID:27288545] Yoon EK, et al. Conservation and Diversification of the SHR-SCR-SCL23 Regulatory Network in the Development of the Functional Endodermis in Arabidopsis Shoots. Mol Plant, 2016. 9(8): p. 1197-1209 [PMID:27353361] Waszczak C, et al. SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions. Plant Cell, 2016. 28(8): p. 1844-59 [PMID:27432873] Yu Q, et al. A P-Loop NTPase Regulates Quiescent Center Cell Division and Distal Stem Cell Identity through the Regulation of ROS Homeostasis in Arabidopsis Root. PLoS Genet., 2016. 12(9): p. e1006175 [PMID:27583367] Sparks EE, et al. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Dev. Cell, 2016. 39(5): p. 585-596 [PMID:27923776] Hirano Y, et al. Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD. Nat Plants, 2017. 3: p. 17010 [PMID:28211915] Henry S, et al. SHR overexpression induces the formation of supernumerary cell layers with cortex cell identity in rice. Dev. Biol., 2017. 425(1): p. 1-7 [PMID:28263767] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Kobayashi A,Miura S,Kozaki A INDETERMINATE DOMAIN PROTEIN binding sequences in the 5'-untranslated region and promoter of the SCARECROW gene play crucial and distinct roles in regulating SCARECROW expression in roots and leaves. Plant Mol. Biol., 2017. 94(1-2): p. 1-13 [PMID:28324206] Díaz-Triviño S,Long Y,Scheres B,Blilou I Analysis of a Plant Transcriptional Regulatory Network Using Transient Expression Systems. Methods Mol. Biol., 2017. 1629: p. 83-103 [PMID:28623581] Long Y, et al. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 2017. 548(7665): p. 97-102 [PMID:28746306] Yu Q, et al. Cell-Fate Specification in Arabidopsis Roots Requires Coordinative Action of Lineage Instruction and Positional Reprogramming. Plant Physiol., 2017. 175(2): p. 816-827 [PMID:28821591] Spiegelman Z,Lee CM,Gallagher KL KinG Is a Plant-Specific Kinesin That Regulates Both Intra- and Intercellular Movement of SHORT-ROOT. Plant Physiol., 2018. 176(1): p. 392-405 [PMID:29122988] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]