PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_549_iso_3
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family WRKY
Protein Properties Length: 531aa    MW: 57608.4 Da    PI: 6.9608
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_549_iso_3genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY108.33.8e-34242298259
                                         --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                                WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                                         dDgynWrKYGqK+vkgse+prsYY+Ct+++Cpvkkkvers+ d++v+ei+Y+g+Hnh+
  cra_locus_549_iso_3_len_2373_ver_3 242 DDGYNWRKYGQKQVKGSEYPRSYYKCTHQNCPVKKKVERSQ-DGQVTEIIYKGQHNHP 298
                                         8****************************************.***************8 PP
2WRKY107.85.5e-34419477159
                                         ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                                WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                                         ldDgy+WrKYGqK+vkg+++prsYY+Cts+gC+v+k+ver+a+dpk+v++tYeg+Hnh+
  cra_locus_549_iso_3_len_2373_ver_3 419 LDDGYRWRKYGQKVVKGNPYPRSYYKCTSPGCNVRKHVERAATDPKAVITTYEGKHNHD 477
                                         59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.802.6E-30237300IPR003657WRKY domain
SuperFamilySSF1182903.14E-27239300IPR003657WRKY domain
SMARTSM007746.8E-39241299IPR003657WRKY domain
PfamPF031061.2E-26242298IPR003657WRKY domain
PROSITE profilePS5081124.88242300IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.7E-37404479IPR003657WRKY domain
SuperFamilySSF1182909.29E-30411479IPR003657WRKY domain
PROSITE profilePS5081138.813414479IPR003657WRKY domain
SMARTSM007746.9E-40419478IPR003657WRKY domain
PfamPF031062.8E-26420477IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009723Biological Processresponse to ethylene
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:1900150Biological Processregulation of defense response to fungus
GO:1900425Biological Processnegative regulation of defense response to bacterium
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 531 aa     Download sequence    Send to blast
MAQNHGSSSS RAPVRPTITL PPRSSVESLF TGGPGASPGP MTLVSSFFSE NDPDSDCRSF  60
SQLLAGAMNS PAPVPVPREN NQVPSISQQM ENSNSSIKEG GAAGGGDAEF RFQQNRPAGL  120
MVGQSPMFTI PPGLSPATLL DSPGFFTPGQ GAFGMSHQQI LAQVTAQSAQ AQAQMHIPAD  180
YSSLSSAPAS QLSQLQSLAP TTTAHQQMPP PVLDSNIIKE SSDVSHSDQR SQASILVDKP  240
ADDGYNWRKY GQKQVKGSEY PRSYYKCTHQ NCPVKKKVER SQDGQVTEII YKGQHNHPPP  300
QLSKRAKDSG NPNGTLNLQG NSELGSKAEN LNNSKEGFPS HSLPMKDQES SQATEHVSGS  360
SDSEEVGDTG NGVDGRDEDE PEAKRRNIEV QTSEPAASSH RTVTEPRIIV QTTSEVDLLD  420
DGYRWRKYGQ KVVKGNPYPR SYYKCTSPGC NVRKHVERAA TDPKAVITTY EGKHNHDVPA  480
AKNSSHSTAS IASQLKPHNA FADNQSTNWR TDFRNDQNQM ALLRFKEEQI I
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A5e-44242480878Probable WRKY transcription factor 4
2lex_A5e-44242480878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027154642.10.0probable WRKY transcription factor 4
SwissprotQ9XI901e-176WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A068TVV40.0A0A068TVV4_COFCA; Uncharacterized protein
STRINGXP_009619961.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA41072445
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]