PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

TALE

Protein Properties

Length: 325aa MW: 36858 Da PI: 5.0562

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_53427_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	27	7.7e-09	267	302	20	55
HHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS Homeobox 20 eknrypsaeereeLAkklgLterqVkvWFqNrRake 55 +k +yp+++++ LA+ +gL+++q+ +WF N+R ++ cra_locus_53427_iso_1_len_1052_ver_3 267 YKWPYPTEADKISLAETTGLDQKQINNWFINQRKRH 302 4679*****************************885 PP
2	ELK	21.6	5.1e-08	222	243	1	22
ELK 1 ELKhqLlrKYsgyLgsLkqEFs 22 ELK+ Llr +++++sLk EFs cra_locus_53427_iso_1_len_1052_ver_3 222 ELKDKLLRRCGSHISSLKLEFS 243 9********************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01255	3.2E-19	91	135	IPR005540	KNOX1
Pfam	PF03790	1.8E-20	93	133	IPR005540	KNOX1
SMART	SM01256	6.0E-21	145	193	IPR005541	KNOX2
Pfam	PF03791	6.8E-23	146	192	IPR005541	KNOX2
Pfam	PF03789	1.1E-5	222	243	IPR005539	ELK domain
SMART	SM01188	4.9E-4	222	243	IPR005539	ELK domain
PROSITE profile	PS50071	12.957	242	305	IPR001356	Homeobox domain
SuperFamily	SSF46689	2.91E-19	243	316	IPR009057	Homeodomain-like
SMART	SM00389	5.8E-13	244	309	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	9.3E-28	247	306	IPR009057	Homeodomain-like
CDD	cd00086	2.47E-13	254	306	No hit	No description
Pfam	PF05920	8.4E-18	262	301	IPR008422	Homeobox KN domain
PROSITE pattern	PS00027	0	280	303	IPR017970	Homeobox, conserved site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010073	Biological Process	meristem maintenance
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 325 aa Download sequence Send to blast
MDEMYGLHST GGDDYAERAL MSDPDNLIIP AVDYLQYEHP YGSMLPSDGD RRNIPVFGSE 60 DLGFQCSAAA SESVSINAHN NHGEAHAAVS TVIKSKIASH PSYPKLIDAY IDCQKVGAPP 120 EIASLLDEIR REKEFCKYRN LIPISLGTDP ELDEFMETYY DILVKYKSDL SRPFDEASSF 180 LHNIETQLGN LCKDDGALSS DDELSGGETE TPDAQTRSED RELKDKLLRR CGSHISSLKL 240 EFSKKKKKGK LPKESRQTLL EWWNVHYKWP YPTEADKISL AETTGLDQKQ INNWFINQRK 300 RHWKPSENMQ LAIMNNLSGH FFADX

Functional Description ? help Back to Top
Source	Description
UniProt	Plays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269\|PubMed:16798887}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269\|PubMed:11311158, ECO:0000269\|PubMed:16798887}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011071110.1	1e-156	homeobox protein knotted-1-like 6 isoform X1
Swissprot	Q84JS6	1e-124	KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBL	A0A2G9GWW1	1e-150	A0A2G9GWW1_9LAMI; Transcription factor MEIS1
STRING	EOY00544	1e-138	(Theobroma cacao)
STRING	Lus10029125	1e-138	(Linum usitatissimum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA753	24	80

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006]