PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

GRAS

Protein Properties

Length: 488aa MW: 55456.5 Da PI: 6.2027

Description

GRAS family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_5198_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	GRAS	327.9	1.9e-100	140	487	3	345
GRAS 3 elLlecAeavssgdlelaqalLarlselaspdgdpmqRlaayfteALaarlarsvselykalppsetseknsse 76 + Lle A+ +++++ +++q+l++ l+el+sp+gd+ q+la+yf++AL +r+++s++++y++l + ++++ + ++ cra_locus_5198_iso_1_len_1504_ver_3 140 DILLETAKSIADKNSNRVQQLMWMLNELSSPYGDTDQKLASYFLQALFNRMTDSGERCYRTLISASEKTCSFES 213 579********************************************************9666555444444 PP GRAS 77 elaalklfsevsPilkfshltaNqaIleavegeervHiiDfdisqGlQWpaLlqaLasRpegppslRiTgvgsp 150 + + + f+evsP+ +f+h+++N aI+ea+ege+++HiiD++ + ++QWp+Ll+aLa+R++++p+lR+T+v+ cra_locus_5198_iso_1_len_1504_ver_3 214 TRKLVLKFQEVSPWTTFGHVACNGAIMEAFEGENKLHIIDISNTFCTQWPTLLEALATRTDETPHLRLTAVVVT 287 4444445**************************************************************8 PP GRAS 151 esg.....skeeleetgerLakfAeelgvpfefnvlvak.rledleleeLrvkpgEalaVnlvlqlhrlldesv 218 +sg ++ ++e+g+r++kfA+ +gvpf+fnvl+++ +l+dl+l eL++k++Eala+n+v +lh++ cra_locus_5198_iso_1_len_1504_ver_3 288 KSGgssggAQKVMKEIGSRMEKFARLMGVPFKFNVLHHTgDLSDLNLAELEIKEDEALAINSVGALHSVS---- 357 8889999999**********************8888*************************8.... PP GRAS 219 sleserdevLklvkslsPkvvvvveqeadhnse....sFlerflealeyysalfdsleaklpreseerikvEre 288 ++ ++rd +++++++l+P++v+vve+ead++ + +F+++f ++l+++ + f+sl++++p++s+er ++Er+ cra_locus_5198_iso_1_len_1504_ver_3 358 PIGNRRDYLISIFRRLQPRIVTVVEEEADLEIGvdgfEFVKGFQQCLNWFRVYFESLDESFPKTSNERLMLERQ 431 99999******************99855455669******************************** PP GRAS 289 llgreivnvvacegaerrerhetlekWrerleeaGFkpvplsekaakqaklllrkvk 345 gr+iv++vac +e++er+et+++W++rl++ GF pv++s+++ +++++llr++ cra_locus_5198_iso_1_len_1504_ver_3 432 -AGRAIVDLVACPPSESIERRETAARWSHRLHAGGFVPVSFSDEVCDDVRALLRRYT 487 .***************************************************985 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50985	49.852	112	488	IPR005202	Transcription factor GRAS
Pfam	PF03514	6.6E-98	140	487	IPR005202	Transcription factor GRAS

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008356	Biological Process	asymmetric cell division
GO:0009956	Biological Process	radial pattern formation
GO:0045930	Biological Process	negative regulation of mitotic cell cycle
GO:0048366	Biological Process	leaf development
GO:0055072	Biological Process	iron ion homeostasis
GO:0005634	Cellular Component	nucleus
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 488 aa Download sequence Send to blast
MDTLFRLVSL QSDQSFNSTS RTNSSSSKSS KQNHFHHQED QEEEECFNFF MDEEDFSSSS 60 SKHNYNPYHH HQPSTTPTPT TTTPTTSTPP THQHHQPYES SSSXHHHQQQ QQQHHHFSFS 120 PAHDISLEFA SSFSGKWSLD ILLETAKSIA DKNSNRVQQL MWMLNELSSP YGDTDQKLAS 180 YFLQALFNRM TDSGERCYRT LISASEKTCS FESTRKLVLK FQEVSPWTTF GHVACNGAIM 240 EAFEGENKLH IIDISNTFCT QWPTLLEALA TRTDETPHLR LTAVVVTKSG GSSGGAQKVM 300 KEIGSRMEKF ARLMGVPFKF NVLHHTGDLS DLNLAELEIK EDEALAINSV GALHSVSPIG 360 NRRDYLISIF RRLQPRIVTV VEEEADLEIG VDGFEFVKGF QQCLNWFRVY FESLDESFPK 420 TSNERLMLER QAGRAIVDLV ACPPSESIER RETAARWSHR LHAGGFVPVS FSDEVCDDVR 480 ALLRRYTQ

Sequence ? help Back to Top

Protein Sequence Length: 488 aa Download sequence Send to blast

MDTLFRLVSL QSDQSFNSTS RTNSSSSKSS KQNHFHHQED QEEEECFNFF MDEEDFSSSS  60
SKHNYNPYHH HQPSTTPTPT TTTPTTSTPP THQHHQPYES SSSXHHHQQQ QQQHHHFSFS  120
PAHDISLEFA SSFSGKWSLD ILLETAKSIA DKNSNRVQQL MWMLNELSSP YGDTDQKLAS  180
YFLQALFNRM TDSGERCYRT LISASEKTCS FESTRKLVLK FQEVSPWTTF GHVACNGAIM  240
EAFEGENKLH IIDISNTFCT QWPTLLEALA TRTDETPHLR LTAVVVTKSG GSSGGAQKVM  300
KEIGSRMEKF ARLMGVPFKF NVLHHTGDLS DLNLAELEIK EDEALAINSV GALHSVSPIG  360
NRRDYLISIF RRLQPRIVTV VEEEADLEIG VDGFEFVKGF QQCLNWFRVY FESLDESFPK  420
TSNERLMLER QAGRAIVDLV ACPPSESIER RETAARWSHR LHAGGFVPVS FSDEVCDDVR  480
ALLRRYTQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_B	0.0	97	488	2	389	Protein SHORT-ROOT
5b3h_E	0.0	97	488	2	389	Protein SHORT-ROOT
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor required for quiescent center cells specification and maintenance of surrounding stem cells, and for the asymmetric cell division involved in radial pattern formation in roots. Essential for both cell division and cell specification. Regulates the radial organization of the shoot axial organs and is required for normal shoot gravitropism. Directly controls the transcription of SCR, and when associated with SCR, of MGP, RLK, TRI, NUC and SCL3. {ECO:0000269\|PubMed:10850497, ECO:0000269\|PubMed:12569126, ECO:0000269\|PubMed:15314023, ECO:0000269\|PubMed:16640459, ECO:0000269\|PubMed:17446396, ECO:0000269\|PubMed:9670559}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027178958.1	0.0	protein SHORT-ROOT
Swissprot	Q9SZF7	0.0	SHR_ARATH; Protein SHORT-ROOT
TrEMBL	A0A068U370	0.0	A0A068U370_COFCA; Uncharacterized protein
STRING	VIT_07s0129g00030.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2031	24	64

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Muraro D, et al. Integration of hormonal signaling networks and mobile microRNAs is required for vascular patterning in Arabidopsis roots. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(2): p. 857-62 [PMID:24381155] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Gao X,Wang C,Cui H Identification of bundle sheath cell fate factors provides new tools for C3-to-C4 engineering. Plant Signal Behav, 2018. [PMID:24819776] Ahrazem O, et al. Ectopic expression of a stress-inducible glycosyltransferase from saffron enhances salt and oxidative stress tolerance in Arabidopsis while alters anchor root formation. Plant Sci., 2015. 234: p. 60-73 [PMID:25804810] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Miguel A,Milhinhos A,Novák O,Jones B,Miguel CM The SHORT-ROOT-like gene PtSHR2B is involved in Populus phellogen activity. J. Exp. Bot., 2016. 67(5): p. 1545-55 [PMID:26709311] Gong X, et al. SEUSS Integrates Gibberellin Signaling with Transcriptional Inputs from the SHR-SCR-SCL3 Module to Regulate Middle Cortex Formation in the Arabidopsis Root. Plant Physiol., 2016. 170(3): p. 1675-83 [PMID:26818732] Kim ES, et al. HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots. Physiol Plant, 2016. 157(2): p. 221-33 [PMID:26968317] Lee SA, et al. Interplay between ABA and GA Modulates the Timing of Asymmetric Cell Divisions in the Arabidopsis Root Ground Tissue. Mol Plant, 2016. 9(6): p. 870-84 [PMID:26970019] Li Q,Zhao Y,Yue M,Xue Y,Bao S The Protein Arginine Methylase 5 (PRMT5/SKB1) Gene Is Required for the Maintenance of Root Stem Cells in Response to DNA Damage. J Genet Genomics, 2016. 43(4): p. 187-97 [PMID:27090604] Clark NM, et al. Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. Elife, 2017. [PMID:27288545] Yoon EK, et al. Conservation and Diversification of the SHR-SCR-SCL23 Regulatory Network in the Development of the Functional Endodermis in Arabidopsis Shoots. Mol Plant, 2016. 9(8): p. 1197-1209 [PMID:27353361] Waszczak C, et al. SHORT-ROOT Deficiency Alleviates the Cell Death Phenotype of the Arabidopsis catalase2 Mutant under Photorespiration-Promoting Conditions. Plant Cell, 2016. 28(8): p. 1844-59 [PMID:27432873] Yu Q, et al. A P-Loop NTPase Regulates Quiescent Center Cell Division and Distal Stem Cell Identity through the Regulation of ROS Homeostasis in Arabidopsis Root. PLoS Genet., 2016. 12(9): p. e1006175 [PMID:27583367] Sparks EE, et al. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Dev. Cell, 2016. 39(5): p. 585-596 [PMID:27923776] Hirano Y, et al. Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD. Nat Plants, 2017. 3: p. 17010 [PMID:28211915] Henry S, et al. SHR overexpression induces the formation of supernumerary cell layers with cortex cell identity in rice. Dev. Biol., 2017. 425(1): p. 1-7 [PMID:28263767] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Kobayashi A,Miura S,Kozaki A INDETERMINATE DOMAIN PROTEIN binding sequences in the 5'-untranslated region and promoter of the SCARECROW gene play crucial and distinct roles in regulating SCARECROW expression in roots and leaves. Plant Mol. Biol., 2017. 94(1-2): p. 1-13 [PMID:28324206] Díaz-Triviño S,Long Y,Scheres B,Blilou I Analysis of a Plant Transcriptional Regulatory Network Using Transient Expression Systems. Methods Mol. Biol., 2017. 1629: p. 83-103 [PMID:28623581] Long Y, et al. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 2017. 548(7665): p. 97-102 [PMID:28746306] Yu Q, et al. Cell-Fate Specification in Arabidopsis Roots Requires Coordinative Action of Lineage Instruction and Positional Reprogramming. Plant Physiol., 2017. 175(2): p. 816-827 [PMID:28821591] Spiegelman Z,Lee CM,Gallagher KL KinG Is a Plant-Specific Kinesin That Regulates Both Intra- and Intercellular Movement of SHORT-ROOT. Plant Physiol., 2018. 176(1): p. 392-405 [PMID:29122988] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]