PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

HD-ZIP

Protein Properties

Length: 724aa MW: 79957.3 Da PI: 6.9266

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_5090_iso_7	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	59.5	5.4e-19	20	78	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le+l++++++ps +r++L +++ +++ +q+kvWFqNrR +ek+ cra_locus_5090_iso_7_len_3116_ver_3 20 KYVRYTPEQVEALERLYHECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 78 5679*****************************************************97 PP
2	START	153	2.5e-48	164	358	2	205
HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT CS START 2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdet 75 +aee+++e+++ka+ ++ Wv+++ +++g ea+ra+g+v +++ v+e+l+d++ W ++ cra_locus_5090_iso_7_len_3116_ver_3 164 IAEETLTEFLSKATGTAVEWVQMPGMKPG--------------PEASRACGLVGLEPT-RVAEILKDRPSWYRD 222 7899******************55554..............479********.8888888888* PP -SEEEEEEEECTT..EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TTSE CS START 76 lakaetlevissg..galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sssvv 143 ++ +++l++ s+g g+++l +++l+a+++l+p Rdf+ +Ry+ +++g++v++++S++++q+ p +++v cra_locus_5090_iso_7_len_3116_ver_3 223 CRTVDILNAMSTGngGTIELLYMQLYAPTTLAPaRDFWLLRYTSVMEDGSLVVCERSLNNTQNGPAmppVHHFV 296 ***********************************************************9998889 PP E-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXX CS START 144 RaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegaktwvatlqrqce 205 Rae+lpSg+li+p+++g+s +++v+h dl+ +++++++r+l++s++ ++t++a+l+++++ cra_locus_5090_iso_7_len_3116_ver_3 297 RAEMLPSGYLIRPCEGGGSIIHIVDHLDLEPWSVPEVIRPLYESSTLLSQRTTMAALRQLRQ 358 ********************************************************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.775	15	79	IPR001356	Homeobox domain
SMART	SM00389	1.3E-15	17	83	IPR001356	Homeobox domain
SuperFamily	SSF46689	4.06E-17	19	83	IPR009057	Homeodomain-like
CDD	cd00086	9.97E-17	20	80	No hit	No description
Pfam	PF00046	1.4E-16	21	78	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	8.4E-19	22	78	IPR009057	Homeodomain-like
CDD	cd14686	1.11E-6	72	111	No hit	No description
PROSITE profile	PS50848	25.657	154	368	IPR002913	START domain
SuperFamily	SSF55961	9.48E-33	155	355	No hit	No description
CDD	cd08875	1.87E-72	158	359	No hit	No description
SMART	SM00234	6.6E-35	163	359	IPR002913	START domain
Gene3D	G3DSA:3.30.530.20	2.1E-22	164	356	IPR023393	START-like domain
Pfam	PF01852	2.3E-45	164	358	IPR002913	START domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009965	Biological Process	leaf morphogenesis
GO:0010014	Biological Process	meristem initiation
GO:0010075	Biological Process	regulation of meristem growth
GO:0010087	Biological Process	phloem or xylem histogenesis
GO:0048263	Biological Process	determination of dorsal identity
GO:0080060	Biological Process	integument development
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0008289	Molecular Function	lipid binding

Sequence ? help Back to Top
Protein Sequence Length: 724 aa Download sequence Send to blast
MAVTSTCKDA ASKMGMDNGK YVRYTPEQVE ALERLYHECP KPSSLRRQQL IRECPILSNI 60 EPKQIKVWFQ NRRCREKQRK EASRLQAVNR KLTAMNKLLM EENDRLQKQV SQLVYENSYF 120 RQHTQNATLA TTDNSCESVV TSGQPHLTPQ HPPRDASPAG LLSIAEETLT EFLSKATGTA 180 VEWVQMPGMK PGPEASRACG LVGLEPTRVA EILKDRPSWY RDCRTVDILN AMSTGNGGTI 240 ELLYMQLYAP TTLAPARDFW LLRYTSVMED GSLVVCERSL NNTQNGPAMP PVHHFVRAEM 300 LPSGYLIRPC EGGGSIIHIV DHLDLEPWSV PEVIRPLYES STLLSQRTTM AALRQLRQIS 360 QEVSQPTVTG WGRRPAALRA LGQRLSKGFN EAVNGFTDEG WSMIESDGID DVTVLVNSSP 420 SKLMGANFNY ANGFSSFSNA VLCAKASMLL QNVPPAILLR FLREHRSEWA DSGIDAYSAA 480 AVKAGPCSLP VSRVGGSFGG QVILPLAHTI EHEEFMEVIR LENMSHYRED MIMPGDIFLL 540 QLCSGVDENA VGTCSELIFA PIDASFSDDA PLLPSGFRII PLDSKVDPSS PNRTLDLAST 600 LEVGPSGNKV SGENSRHSGS AKSVMTIAFQ FAFEMHLQEN VAAMARQYVR SIISSVQRVA 660 LALSPSSLGP NAGLRTPPGT PEAQTLARWI CQSYRYDAGL IYSALVCSRH CFHKLTISMM 720 YYFA

Sequence ? help Back to Top

Protein Sequence Length: 724 aa Download sequence Send to blast

MAVTSTCKDA ASKMGMDNGK YVRYTPEQVE ALERLYHECP KPSSLRRQQL IRECPILSNI  60
EPKQIKVWFQ NRRCREKQRK EASRLQAVNR KLTAMNKLLM EENDRLQKQV SQLVYENSYF  120
RQHTQNATLA TTDNSCESVV TSGQPHLTPQ HPPRDASPAG LLSIAEETLT EFLSKATGTA  180
VEWVQMPGMK PGPEASRACG LVGLEPTRVA EILKDRPSWY RDCRTVDILN AMSTGNGGTI  240
ELLYMQLYAP TTLAPARDFW LLRYTSVMED GSLVVCERSL NNTQNGPAMP PVHHFVRAEM  300
LPSGYLIRPC EGGGSIIHIV DHLDLEPWSV PEVIRPLYES STLLSQRTTM AALRQLRQIS  360
QEVSQPTVTG WGRRPAALRA LGQRLSKGFN EAVNGFTDEG WSMIESDGID DVTVLVNSSP  420
SKLMGANFNY ANGFSSFSNA VLCAKASMLL QNVPPAILLR FLREHRSEWA DSGIDAYSAA  480
AVKAGPCSLP VSRVGGSFGG QVILPLAHTI EHEEFMEVIR LENMSHYRED MIMPGDIFLL  540
QLCSGVDENA VGTCSELIFA PIDASFSDDA PLLPSGFRII PLDSKVDPSS PNRTLDLAST  600
LEVGPSGNKV SGENSRHSGS AKSVMTIAFQ FAFEMHLQEN VAAMARQYVR SIISSVQRVA  660
LALSPSSLGP NAGLRTPPGT PEAQTLARWI CQSYRYDAGL IYSALVCSRH CFHKLTISMM  720
YYFA

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269\|PubMed:11402194, ECO:0000269\|PubMed:15598805}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00200	DAP	Transfer from AT1G52150	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. Repressed by miR165. {ECO:0000269\|PubMed:17237362, ECO:0000269\|PubMed:8575317}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027084668.1	0.0	homeobox-leucine zipper protein ATHB-15-like
Swissprot	Q39123	0.0	ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBL	A0A068UKR5	0.0	A0A068UKR5_COFCA; Uncharacterized protein
STRING	Gorai.009G049100.1	0.0	(Gossypium raimondii)

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis. Planta, 2014. 239(5): p. 989-1001 [PMID:24488524] Baima S, et al. Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module. Mol Plant, 2014. 7(6): p. 1006-1025 [PMID:24777988] Kakehi J, et al. Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana. PLoS ONE, 2015. 10(1): p. e0117309 [PMID:25625317] Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Liu S, et al. Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis. Front Plant Sci, 2015. 6: p. 388 [PMID:26082787] Yamaguchi YL, et al. Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots. Front Plant Sci, 2017. 8: p. 1195 [PMID:28747918] Yamazaki K, et al. Suppression of DELLA signaling induces procambial cell formation in culture. Plant J., 2018. 94(1): p. 48-59 [PMID:29383774]