PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_2511_iso_5
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family ARF
Protein Properties Length: 849aa    MW: 94280.1 Da    PI: 6.5458
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_2511_iso_5genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B376.52.9e-24179280199
                                          EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHH CS
                                   B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeF 68 
                                          f+k+lt sd++++g +++p++ ae++      +++ + s++l+ +d++g +W++++iyr++++r++lt+GW+ F
  cra_locus_2511_iso_5_len_3511_ver_3 179 FCKTLTASDTSTHGGFSVPRRAAEDCfppldyKEQ-RPSQELVAKDLHGTEWKFRHIYRGQPRRHLLTTGWSIF 251
                                          99****************************86333.45679********************************* PP

                                          HHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
                                   B3  69 vkangLkegDfvvFkldgrsefelvvkvfrk 99 
                                          v++++L +gD v+F   + +++el+++++r+
  cra_locus_2511_iso_5_len_3511_ver_3 252 VSQKNLVSGDAVLFL--RGEGGELRLGIRRA 280
                                          ***************..4499*******996 PP
2Auxin_resp1027.7e-34305386182
                           Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrW 74 
                                          +a+a+s++ +F+++Y+Pras ++F+ +++k++k++++k+ vG+Rfk++++ +ds+err+sG+v+gv d+d +rW
  cra_locus_2511_iso_5_len_3511_ver_3 305 VANAVSSNGTFQIFYSPRASYADFILPYQKYVKSITNKIPVGTRFKIRVDLDDSPERRYSGVVTGVGDADHSRW 378
                                          689*********************************************************************** PP

                           Auxin_resp  75 pnSkWrsL 82 
                                          pnSkWr+L
  cra_locus_2511_iso_5_len_3511_ver_3 379 PNSKWRCL 386
                                          *******9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.62E-43170290IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.5E-40172291IPR015300DNA-binding pseudobarrel domain
CDDcd100171.01E-22177279No hitNo description
PfamPF023624.4E-22179280IPR003340B3 DNA binding domain
PROSITE profilePS5086313.183179281IPR003340B3 DNA binding domain
SMARTSM010191.5E-23179281IPR003340B3 DNA binding domain
PfamPF065077.8E-29305386IPR010525Auxin response factor
SuperFamilySSF542771.18E-10712800No hitNo description
PROSITE profilePS5174521.172721805IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0010050Biological Processvegetative phase change
GO:0010158Biological Processabaxial cell fate specification
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 849 aa     Download sequence    Send to blast
MEIDLNHAVE TEVEKKNACS CNGECADKGG SCGCGCVYCS LSSSTSSCSS NASSSSSPVS  60
PSKMFMELWY ACAGPLTSLP KKGNVVVYFP QGHLEQASSV SSFPALEVPT FDLQPQIFCR  120
VLEVELLANK ENDEVYTQLT LLPISELQAI RLEGKEREED GADEDGNGGV PIKSTSHMFC  180
KTLTASDTST HGGFSVPRRA AEDCFPPLDY KEQRPSQELV AKDLHGTEWK FRHIYRGQPR  240
RHLLTTGWSI FVSQKNLVSG DAVLFLRGEG GELRLGIRRA AGPRNGLSDS IIKNQHSYPN  300
VLAPVANAVS SNGTFQIFYS PRASYADFIL PYQKYVKSIT NKIPVGTRFK IRVDLDDSPE  360
RRYSGVVTGV GDADHSRWPN SKWRCLMVRW DEDPLSNHQE RVSPWEIDFS ASFPTLNIQT  420
SPRMKKLRTS LQADLHNGSP NCSDLLFPGL HSENATSAQK DVFLPSPWNG YIPGHGSLWD  480
FAESVRSGKV LQGQENLGLV SPLYGRDKIN RQLDFEMHPI AAHHNNIVLN RMEKSNYSEL  540
GRIQPSASFS GSLETNSFPR VLQGQEICSL KSLTRKTELN PGAWRKPEFS CNVFNVNQRL  600
APNCYPLASE GIRNMVLPFS GVYKTGQDPV MLSYMSNFQR DNHVLNTNSV RDGLSRDEKR  660
ILPVANDQKT LEKTSLFPIS GMPLKDKNDE NSKGAGGACK IFGFSLTEEP PNSTSQGSNR  720
RSCTKVHKQG SLVGRAIDLS RLYSYDDLMI ELERLFSMEG LLRDPSKGWR VLYTDSENDM  780
MVVGDDPWHE FCEVVSKIHI YTQEEVEKMS IGIFGDDTQS CLEEAPHVAD VSKSSSVSPP  840
YSSPTVVRL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-113474082353Auxin response factor 1
4ldw_A1e-113474082353Auxin response factor 1
4ldw_B1e-113474082353Auxin response factor 1
4ldx_A1e-113474082353Auxin response factor 1
4ldx_B1e-113474082353Auxin response factor 1
4ldy_A1e-113474082353Auxin response factor 1
4ldy_B1e-113474082353Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027086520.10.0auxin response factor 4-like isoform X2
SwissprotQ9ZTX90.0ARFD_ARATH; Auxin response factor 4
TrEMBLA0A068UF770.0A0A068UF77_COFCA; Auxin response factor
STRINGPGSC0003DMT4000208390.0(Solanum tuberosum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA51432234
Publications ? help Back to Top
  1. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  2. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  3. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  4. Matsumura Y, et al.
    A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis.
    Biol Open, 2016. 5(7): p. 942-54
    [PMID:27334696]
  5. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  6. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]