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PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Home TFext BLAST Prediction Download Help About Links PlantRegMap |
Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | cra_locus_16044_iso_1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
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Family | bHLH | ||||||||
Protein Properties | Length: 646aa MW: 73182.5 Da PI: 5.4998 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 39.4 | 1e-12 | 441 | 488 | 3 | 55 |
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 r+h ++Er+RR+++ ++f L +l+P++ +K++K++iL ++eY+k+L+ cra_locus_16044_iso_1_len_2499_ver_3 441 RNHVMAERKRREKLHERFTLLGSLVPSS-----GKVDKVSILDDTIEYLKELE 488 589************************9.....9****************996 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF14215 | 3.3E-54 | 15 | 198 | IPR025610 | Transcription factor MYC/MYB N-terminal |
PROSITE profile | PS50888 | 16.044 | 438 | 487 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SuperFamily | SSF47459 | 4.84E-17 | 441 | 504 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 3.3E-10 | 441 | 488 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 1.23E-10 | 441 | 485 | No hit | No description |
Gene3D | G3DSA:4.10.280.10 | 6.3E-17 | 442 | 499 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 4.2E-15 | 444 | 493 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0009957 | Biological Process | epidermal cell fate specification | ||||
GO:0010091 | Biological Process | trichome branching | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 646 aa Download sequence Send to blast |
MEIQLQDQNG AAENLKRQLA LAVKSIQWSY AIFWSISSRQ PGVLEWGEGY YNGDIKTRKT 60 IQAGELSVDQ LGLQRSEQLR ELYESLSAAE SNPQAKRPSA ALSPEDLTDT EWYFLVCMSF 120 VFNIGQGLPG RSLAKNQAIW LCNAHQADSK VFTRSLLAKS ADIQTVFCFP YLGGIVELGV 180 TELVSEDRNL IQHIKTNFLD NPNAVISKIP NYVSNNPRND KDFMCANPVK DILEADFSPL 240 IECENVQVSS PKSSSNGFES NQPGEESFMI EAINGEASQV QSWQFMDDEI SNCIHNSMNS 300 SDCISQTYAN PKRMVPPLYD EKVNNNFLHD LHECNQKKLD SFDFKSDDVH YQNVLSTLLK 360 SSHQLILGPH CRKNNMESSF VNWKKERSVV FQKPRCATSQ RVLKKVLFEV TKMHGDLIPE 420 SSKENGKKES IWRPEADEID RNHVMAERKR REKLHERFTL LGSLVPSSGK VDKVSILDDT 480 IEYLKELERR VEELESQKEV GELEGRTRRR PQQEGTERIS DSYGSNRTAN NNNRKSLINK 540 RKASDVEEME HETECCMMIG GESSSEDVTV SVIDKNVLIE INCPWKESVL LEIMEGLTDL 600 NLESQAVQSS NTDGILSLTI KCKFKGSRIA SASMIRQALQ RIVRKS |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4rqw_A | 1e-16 | 13 | 198 | 7 | 192 | Transcription factor MYC3 |
4rqw_B | 1e-16 | 13 | 198 | 7 | 192 | Transcription factor MYC3 |
4rs9_A | 1e-16 | 13 | 198 | 7 | 192 | Transcription factor MYC3 |
4yz6_A | 1e-16 | 13 | 198 | 7 | 192 | Transcription factor MYC3 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 446 | 451 | ERKRRE |
2 | 447 | 452 | RKRREK |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator, when associated with MYB75/PAP1, MYB90/PAP2 or TT2. Involved in epidermal cell fate specification. Regulates negatively stomata formation, but, in association with TTG1 and MYB0/GL1, promotes trichome formation, branching and endoreplication. Regulates also trichome cell wall maturation. Together with MYB66/WER, promotes the formation of non-hair cells in root epidermis cells in the N position. Whereas together with CPC, promotes the formation of hair cells in root epidermis cells in the H position by inhibiting non-hair cell formation. Seems also to play a role in the activation of anthocyanin biosynthesis, probably together with MYB75/PAP1. Activates the transcription of GL2. {ECO:0000269|PubMed:11063707, ECO:0000269|PubMed:12917293, ECO:0000269|PubMed:12956536, ECO:0000269|PubMed:14561633, ECO:0000269|PubMed:14627722, ECO:0000269|PubMed:15361138, ECO:0000269|PubMed:15590742}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: By nitrogen deficiency and UV light. Negatively regulated by MYB66/WER, GL3 and BHLH2 in the developing non-hair cells, and positively regulated by CPC and TRY in the developing hair cells. {ECO:0000269|PubMed:12679534, ECO:0000269|PubMed:15590742, ECO:0000269|PubMed:17053893}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_027181560.1 | 0.0 | transcription factor EGL1-like isoform X1 | ||||
Refseq | XP_027181561.1 | 0.0 | transcription factor EGL1-like isoform X1 | ||||
Refseq | XP_027181562.1 | 0.0 | transcription factor EGL1-like isoform X1 | ||||
Swissprot | Q9FN69 | 0.0 | GL3_ARATH; Transcription factor GLABRA 3 | ||||
TrEMBL | A0A2U9IY29 | 0.0 | A0A2U9IY29_CATRO; Transcription factor GLABRA 3 | ||||
STRING | EOY24750 | 0.0 | (Theobroma cacao) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA4576 | 24 | 35 |