PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_15637_iso_2
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family HD-ZIP
Protein Properties Length: 839aa    MW: 91810.6 Da    PI: 5.8888
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_15637_iso_2genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox57.22.9e-182683457
                                          -SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS
                              Homeobox  4 RttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57
                                            ++t+eq+e+Le++++++++ps  +r++L +++    +++ +q+kvWFqNrR +ek+
  cra_locus_15637_iso_2_len_3428_ver_3 26 YVRYTAEQVEALERVYAECPKPSSLRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 83
                                          5789****************************************************97 PP
2START156.22.6e-491653722204
                                           HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-T CS
                                 START   2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWde 74 
                                           +aee+++e+++ka+ ++  Wv+++ +++g++++ +f+ s+++sg a+ra+g+   +++   +e+l+d++ W +
  cra_locus_15637_iso_2_len_3428_ver_3 165 IAEETLAEFLSKATGTAVDWVQMPGMKPGPDSVGIFAISQSCSGVAARACGLASLEPT-KIAEILKDRPSWFR 236
                                           7899******************************************************.7777777777**** PP

                                           T-SEEEEEEEECTT..EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--....-TT CS
                                 START  75 tlakaetlevissg..galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppe...sss 141
                                           ++++ e+      g  g+++l +++ +a+++l+p Rdf+++Ry+ +l  g++v++++S++ +   p+    s+
  cra_locus_15637_iso_2_len_3428_ver_3 237 DCRSLEVFTMSPAGngGTIELVYTQIYAPTTLAPaRDFWTLRYTTTLDNGSLVVCERSLSGTGAGPNpaaASQ 309
                                           ***7777766666566********************************************99999988999** PP

                                           SEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXX CS
                                 START 142 vvRaellpSgiliepksnghskvtwvehvdlkgrlphwllrslvksglaegaktwvatlqrqc 204
                                           ++Rae+lpSg+li+p+++g+s +++v+h +l++++++++lr+l++s+ + ++k++ a+l++ +
  cra_locus_15637_iso_2_len_3428_ver_3 310 FIRAEMLPSGYLIRPCEGGGSIIHIVDHLNLEAWSVPEVLRPLYESSKVVAQKMTIAALRYIR 372
                                           **********************************************************99865 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.602.4E-18783IPR009057Homeodomain-like
PROSITE profilePS5007115.3052084IPR001356Homeobox domain
SMARTSM003892.8E-152288IPR001356Homeobox domain
CDDcd000864.76E-162585No hitNo description
SuperFamilySSF466893.94E-162586IPR009057Homeodomain-like
PfamPF000467.5E-162683IPR001356Homeobox domain
CDDcd146863.66E-677116No hitNo description
PROSITE profilePS5084826.098155383IPR002913START domain
CDDcd088754.60E-69159375No hitNo description
SuperFamilySSF559613.02E-33164376No hitNo description
Gene3DG3DSA:3.30.530.202.8E-18164364IPR023393START-like domain
SMARTSM002344.7E-40164374IPR002913START domain
PfamPF018526.8E-47165372IPR002913START domain
PfamPF086701.5E-49698839IPR013978MEKHLA
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009855Biological Processdetermination of bilateral symmetry
GO:0009944Biological Processpolarity specification of adaxial/abaxial axis
GO:0009956Biological Processradial pattern formation
GO:0010014Biological Processmeristem initiation
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0030154Biological Processcell differentiation
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 839 aa     Download sequence    Send to blast
MAMVAQQQHR ESSSGSINKH MDAGKYVRYT AEQVEALERV YAECPKPSSL RRQQLIRECP  60
ILSNIEPKQI KVWFQNRRCR EKQRKESSRL QTVNRKLTAM NKLLMEENDR LQKQVSQLVC  120
ENGYMRQQLQ SASAATTTDA SCESVVTTPQ HSLRDSNNPA GLLSIAEETL AEFLSKATGT  180
AVDWVQMPGM KPGPDSVGIF AISQSCSGVA ARACGLASLE PTKIAEILKD RPSWFRDCRS  240
LEVFTMSPAG NGGTIELVYT QIYAPTTLAP ARDFWTLRYT TTLDNGSLVV CERSLSGTGA  300
GPNPAAASQF IRAEMLPSGY LIRPCEGGGS IIHIVDHLNL EAWSVPEVLR PLYESSKVVA  360
QKMTIAALRY IRQIAQETSG EVVYGLGRQP AVLRTFSQRL SRGFNDAING YNDDGWSLLS  420
CDGAEDVIIA INSTKNLGTS STSLSLLGGI LCAKASMLLQ NVPPAVLVRF LREHRSEWAD  480
FNVDAYAAAS LKSGSYAYPG MRPTRFTGTQ IIMPLGHTIE HEEMLEVIRL EGHSLGQEDG  540
FMSRDIHLLQ MCSGVDENAV GACSELVFAP IDEMFPDDAP LLPSGFRIIP LESKSGDNTQ  600
DTLTAQRTLD LTSSLEVGPA PSSAAGDTSA SYNARSVLTI AFQFPFENNL QENVATMARQ  660
YLRSVISSVQ RVAMAISPSG MSPTIGPKLS PGSPEALTLA HWICQSYSFH MGAELLRADS  720
VDGESVLKNL WHHQDAILCC SLKSLPVFIF ANQAGLDMLE TTLVALQDVT LDKIFDDSGR  780
KALFAEFAKI MQQGYAYLPG GICMSTMGRH VSYEQAIAWK VMAGDESTVH CLAFTFVNW
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of interfascicular fiber (cortical cells) and secondary xylem differentiation in the inflorescence stems. Required for lateral shoot meristems (LSMs) and flower meristems (FMs) initiation. May be involved in the determination of vascular patterning and organ polarity (PubMed:10559440, PubMed:11169198, PubMed:11402186, PubMed:15111711, PubMed:15598805, PubMed:7555701). Directly regulates the expression of AGO10, ZPR1, ZPR2, ZPR3 and ZPR4 (PubMed:22781836). Required to regulate adaxial-abaxial polarity and leaf axial patterning (PubMed:20807212). {ECO:0000269|PubMed:10559440, ECO:0000269|PubMed:11169198, ECO:0000269|PubMed:11402186, ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:15598805, ECO:0000269|PubMed:20807212, ECO:0000269|PubMed:22781836, ECO:0000269|PubMed:7555701}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. Repressed by ZPR and miR165. Induced by DOF5.1 (PubMed:20807212). {ECO:0000269|PubMed:15111711, ECO:0000269|PubMed:17237362, ECO:0000269|PubMed:20807212}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010651164.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA
RefseqXP_019076130.10.0PREDICTED: homeobox-leucine zipper protein REVOLUTA
SwissprotQ9SE430.0REV_ARATH; Homeobox-leucine zipper protein REVOLUTA
TrEMBLD7SKZ00.0D7SKZ0_VITVI; Uncharacterized protein
STRINGVIT_06s0004g02800.t010.0(Vitis vinifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA45724140
Publications ? help Back to Top
  1. Lian H,Li X,Liu Z,He Y
    HYL1 is required for establishment of stamen architecture with four microsporangia in Arabidopsis.
    J. Exp. Bot., 2013. 64(11): p. 3397-410
    [PMID:23918970]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Baima S, et al.
    Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module.
    Mol Plant, 2014. 7(6): p. 1006-1025
    [PMID:24777988]
  4. Jia X, et al.
    Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic.
    Plant Sci., 2015. 233: p. 11-21
    [PMID:25711809]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Shi B, et al.
    Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis.
    PLoS Genet., 2016. 12(7): p. e1006168
    [PMID:27398935]