PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Alismatales; Zosteraceae; Zostera

Family

bHLH

Protein Properties

Length: 186aa MW: 21068.9 Da PI: 6.9641

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Zosma32g00920.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	42.3	1.4e-13	39	85	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 +h e+Er+RR+++N++f Lr ++P+ + K++Ka+ L A+ YI +Lq Zosma32g00920.1 39 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAISYITELQ 85 799*********************66......***************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	17.13	35	84	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	6.02E-20	38	101	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.95E-15	38	89	No hit	No description
Pfam	PF00010	4.4E-11	39	85	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	2.1E-19	39	97	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	5.7E-17	41	90	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 186 aa Download sequence Send to blast
MDVELLNDDR PAVSTVVTDE RRPRKRGRKP ANGREEPLNH VEAERQRREK LNQRFYALRA 60 VVPNISKMDK ASLLGDAISY ITELQKKLKE MESEKDVQQN SPDVDVQMGN NEVIVHVSTP 120 LETHPVSTVI NVFKETQVDV VDSKFSASNN TVFHTFVVKT QSGSEQMTMG FFFSPLLTMA 180 CERKF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5gnj_A	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_B	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_E	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_F	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_G	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_I	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_M	3e-32	33	95	2	64	Transcription factor MYC2
5gnj_N	3e-32	33	95	2	64	Transcription factor MYC2
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	20	28	RRPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269\|PubMed:30610166}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269\|PubMed:30610166}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024987947.1	2e-75	transcription factor bHLH13
Swissprot	A0A3Q7ELQ2	2e-72	MTB1_SOLLC; Transcription factor MTB1
TrEMBL	A0A0K9NST2	1e-134	A0A0K9NST2_ZOSMR; Uncharacterized protein
STRING	XP_009781532.1	5e-72	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP7385	29	44

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G46510.1	1e-64	ABA-inducible BHLH-type transcription factor

Link Out ? help Back to Top
Phytozome	Zosma32g00920.1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Sun H,Fan HJ,Ling HQ Genome-wide identification and characterization of the bHLH gene family in tomato. BMC Genomics, 2015. 16: p. 9 [PMID:25612924] Liu Y, et al. MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop. Plant Cell, 2019. 31(1): p. 106-127 [PMID:30610166]