PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Alismatales; Zosteraceae; Zostera

Family

C2H2

Protein Properties

Length: 447aa MW: 50127.7 Da PI: 9.3808

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Zosma114g00630.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	18.9	4.1e-06	65	87	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++Cgk F r nL+ H r H Zosma114g00630.1 65 FVCEICGKGFQRDQNLQLHRRGH 87 89*******************88 PP
2	zf-C2H2	12.3	0.00051	141	163	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H +t+ Zosma114g00630.1 141 WKCDKCSKKYAVQSDWKAHSKTC 163 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.34E-7	64	87	No hit	No description
SMART	SM00355	0.012	65	87	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.2E-5	65	87	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	11.614	65	87	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	67	87	IPR007087	Zinc finger, C2H2
SMART	SM00355	110	106	136	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.6E-4	129	162	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	1.34E-7	136	161	No hit	No description
SMART	SM00355	150	141	161	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0044212	Molecular Function	transcription regulatory region DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 447 aa Download sequence Send to blast
MLRREERHLH LQYPPPPPVL EEEPLCQTSP KQPPLKKKRN LPGTPDPGAD VIALSPRSLM 60 ATNRFVCEIC GKGFQRDQNL QLHRRGHNLP WKLKQRSSKE IKKKVYVCPE KTCVHHYPSR 120 ALGDLTGIKK HFSRKHGEKK WKCDKCSKKY AVQSDWKAHS KTCGTREYKC DCGTIFARKD 180 SFITHRAFCD ALTEESMRLS SSIMTAVNDT GSNQLQMGVT GNMYFHNHSS YGTTQDQKPS 240 DISQWLVGRQ MEQSESLPYF NPIRPLPSSS TGGLMEYVPE KNKFQIEDSM APILFSSSNM 300 NNGSHNDSDI MAHMSATALL QKAAQIGASV SNSSSSMFAG LGGLLGRRSV KSLQDHHHNN 360 NNETQTHENA TSCGNAGAGN MRIPEWNQHI NPCHVERRRP TRDFLGLDDG RENSCRPLLM 420 LQQELAKITS MGNNKVDLTN SSGYLH*

Sequence ? help Back to Top

Protein Sequence Length: 447 aa Download sequence Send to blast

MLRREERHLH LQYPPPPPVL EEEPLCQTSP KQPPLKKKRN LPGTPDPGAD VIALSPRSLM  60
ATNRFVCEIC GKGFQRDQNL QLHRRGHNLP WKLKQRSSKE IKKKVYVCPE KTCVHHYPSR  120
ALGDLTGIKK HFSRKHGEKK WKCDKCSKKY AVQSDWKAHS KTCGTREYKC DCGTIFARKD  180
SFITHRAFCD ALTEESMRLS SSIMTAVNDT GSNQLQMGVT GNMYFHNHSS YGTTQDQKPS  240
DISQWLVGRQ MEQSESLPYF NPIRPLPSSS TGGLMEYVPE KNKFQIEDSM APILFSSSNM  300
NNGSHNDSDI MAHMSATALL QKAAQIGASV SNSSSSMFAG LGGLLGRRSV KSLQDHHHNN  360
NNETQTHENA TSCGNAGAGN MRIPEWNQHI NPCHVERRRP TRDFLGLDDG RENSCRPLLM  420
LQQELAKITS MGNNKVDLTN SSGYLH*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	8e-37	137	201	3	67	Zinc finger protein JACKDAW
5b3h_F	8e-37	137	201	3	67	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA sequence 5'-CTTTTGTCC-3' (PubMed:21265895, PubMed:25929516). Regulates photoperiodic flowering by modulating sugar transport and metabolism (PubMed:21265895, PubMed:25929516). Regulates SUS1 and SUS4 (PubMed:21265895). Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:25829440). {ECO:0000269\|PubMed:21265895, ECO:0000269\|PubMed:25829440, ECO:0000269\|PubMed:25929516}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00125	DAP	Transfer from AT1G03840	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by 'SHORT-ROOT' (SHR)(PubMed:16640459). Strongly down-regulated by sugar deprivation, but not regulated by day-length. {ECO:0000269\|PubMed:16640459}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016680913.1	1e-122	PREDICTED: zinc finger protein JACKDAW-like
Swissprot	Q9FFH3	1e-108	IDD8_ARATH; Zinc finger protein NUTCRACKER
TrEMBL	A0A0K9Q2D3	0.0	A0A0K9Q2D3_ZOSMR; Zinc finger protein NUTCRACKER
STRING	Gorai.009G418600.1	1e-121	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP202	38	320

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G44160.1	1e-101	C2H2-like zinc finger protein

Link Out ? help Back to Top
Phytozome	Zosma114g00630.1

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Long Y, et al. In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots. Nature, 2017. 548(7665): p. 97-102 [PMID:28746306]