PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia

Family

NAC

Protein Properties

Length: 560aa MW: 61097 Da PI: 7.2899

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Zmw_sc01917.1.g00130.1	genome	ZGD	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	175.8	1.2e-54	143	272	1	129
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk...kvkaeekewyfFskrdkkyatgkrknrat 78 +ppGfrFhPtdeelv +yL+kkv+++k++l +vi+++d+y++ePwdL++ + e++ewyfFs +d+ky+tg+r+nrat Zmw_sc01917.1.g00130.1.am.mk 143 VPPGFRFHPTDEELVGYYLRKKVASQKIDL-DVIRDIDLYRIEPWDLQEhcgIGYDEQNEWYFFSYKDRKYPTGTRTNRAT 222 69**************************.9***********953432234677****************** PP NAM 79 ksgyWkatgkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrle 129 +g+Wkatg+dk+v++ k++l+g++ktLvfykgrap+g+ktdW+mheyrle Zmw_sc01917.1.g00130.1.am.mk 223 MAGFWKATGRDKAVHD-KSRLIGMRKTLVFYKGRAPNGQKTDWIMHEYRLE 272 ************.999***************************85 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	2.22E-58	140	311	IPR003441	NAC domain
PROSITE profile	PS51005	57.856	143	311	IPR003441	NAC domain
Pfam	PF02365	3.5E-28	144	271	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010200	Biological Process	response to chitin
GO:0048759	Biological Process	xylem vessel member cell differentiation
GO:1901348	Biological Process	positive regulation of secondary cell wall biogenesis
GO:1990110	Biological Process	callus formation
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 560 aa Download sequence Send to blast
MEFLDQATER SEAVQATETH LLLVLPGFSL AILPRPVHAR HAFVAPLDGG DGGPEVAFPL 60 LPAAPPALSK VLNYHARRPA CMQLSKVVQA RALPPPAARQ KLANAISFCY LHYLQGSGVA 120 ESDAHTYSGA APGDHMDSME SCVPPGFRFH PTDEELVGYY LRKKVASQKI DLDVIRDIDL 180 YRIEPWDLQE HCGIGYDEQN EWYFFSYKDR KYPTGTRTNR ATMAGFWKAT GRDKAVHDKS 240 RLIGMRKTLV FYKGRAPNGQ KTDWIMHEYR LETDENAPPQ ARPLAPLSFT PNKLVVVLQE 300 EGWVVCRAFK KRTAYPARSM ALAWDSSFAY RDPNVMVGAT AAEAAAFVDP NKAYAQIRRQ 360 SSKNARFKQE AELDGAAAFL QYSSHLVELP QLESPSAPLA PNTSHASTEE GGSGGGRRSK 420 KARADKVATD WRALDKFVAS QLSPGEGGDI EATASAAAAG EGSQLDHGCE EDMAALLFLN 480 SDGREEVERW TGLLGPASGR WPPLPTRVGL GMHGHGLRPT YVHGPCSHTP VATCDPSLLT 540 NFVVGPSPAG GAADLRRGRD

Sequence ? help Back to Top

Protein Sequence Length: 560 aa Download sequence Send to blast

MEFLDQATER SEAVQATETH LLLVLPGFSL AILPRPVHAR HAFVAPLDGG DGGPEVAFPL  60
LPAAPPALSK VLNYHARRPA CMQLSKVVQA RALPPPAARQ KLANAISFCY LHYLQGSGVA  120
ESDAHTYSGA APGDHMDSME SCVPPGFRFH PTDEELVGYY LRKKVASQKI DLDVIRDIDL  180
YRIEPWDLQE HCGIGYDEQN EWYFFSYKDR KYPTGTRTNR ATMAGFWKAT GRDKAVHDKS  240
RLIGMRKTLV FYKGRAPNGQ KTDWIMHEYR LETDENAPPQ ARPLAPLSFT PNKLVVVLQE  300
EGWVVCRAFK KRTAYPARSM ALAWDSSFAY RDPNVMVGAT AAEAAAFVDP NKAYAQIRRQ  360
SSKNARFKQE AELDGAAAFL QYSSHLVELP QLESPSAPLA PNTSHASTEE GGSGGGRRSK  420
KARADKVATD WRALDKFVAS QLSPGEGGDI EATASAAAAG EGSQLDHGCE EDMAALLFLN  480
SDGREEVERW TGLLGPASGR WPPLPTRVGL GMHGHGLRPT YVHGPCSHTP VATCDPSLLT  540
NFVVGPSPAG GAADLRRGRD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3ulx_A	6e-47	140	315	12	172	Stress-induced transcription factor NAC1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the secondary wall NAC binding element (SNBE), 5'-(T/A)NN(C/T)(T/C/G)TNNNNNNNA(A/C)GN(A/C/T)(A/T)-3', in the promoter of target genes (By similarity). Involved in xylem formation by promoting the expression of secondary wall-associated transcription factors and of genes involved in secondary wall biosynthesis and programmed cell death, genes driven by the secondary wall NAC binding element (SNBE). Triggers thickening of secondary walls (PubMed:25148240). {ECO:0000250\|UniProtKB:Q9LVA1, ECO:0000269\|PubMed:25148240}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00266	DAP	Transfer from AT2G18060	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by chitin (e.g. chitooctaose) (PubMed:17722694). Accumulates in plants exposed to callus induction medium (CIM) (PubMed:17581762). {ECO:0000269\|PubMed:17581762, ECO:0000269\|PubMed:17722694}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022678630.1	0.0	NAC domain-containing protein 37 isoform X1
Swissprot	Q9SL41	1e-116	NAC37_ARATH; NAC domain-containing protein 37
TrEMBL	A0A368SWG2	0.0	A0A368SWG2_SETIT; Uncharacterized protein
STRING	Pavir.Ib00161.1.p	0.0	(Panicum virgatum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP3625	37	68

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Negi S,Tak H,Ganapathi TR Cloning and functional characterization of MusaVND1 using transgenic banana plants. Transgenic Res., 2015. 24(3): p. 571-85 [PMID:25523085] Tan TT, et al. Transcription Factors VND1-VND3 Contribute to Cotyledon Xylem Vessel Formation. Plant Physiol., 2018. 176(1): p. 773-789 [PMID:29133368]