PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Zmw_sc01635.1.g00130.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia
Family TALE
Protein Properties Length: 692aa    MW: 76583.3 Da    PI: 8.9823
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Zmw_sc01635.1.g00130.1genomeZGD-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox25.32.7e-084965341755
                                   HHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
                      Homeobox  17 elFeknrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                                   e+ +k +yps++++  LA+++gL+ +q+ +WF N+R ++
  Zmw_sc01635.1.g00130.1.am.mk 496 EMHYKWPYPSETQKGALAESTGLDLKQINNWFINQRKRH 534
                                   4555789*****************************885 PP

2ELK361.4e-12454475122
                           ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                                   ELKh+Ll+KYsgyL+sLkqE+s
  Zmw_sc01635.1.g00130.1.am.mk 454 ELKHHLLKKYSGYLSSLKQELS 475
                                   9*******************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012558.4E-18259306IPR005540KNOX1
PfamPF037902.8E-20260304IPR005540KNOX1
SMARTSM012562.7E-24313373IPR005541KNOX2
PfamPF037912.4E-16319371IPR005541KNOX2
SMARTSM011884.9E-7454475IPR005539ELK domain
PROSITE profilePS5121311.331454474IPR005539ELK domain
PfamPF037891.8E-9454475IPR005539ELK domain
PROSITE profilePS5007112.584474537IPR001356Homeobox domain
SuperFamilySSF466895.99E-19475550IPR009057Homeodomain-like
SMARTSM003892.2E-12476541IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.8E-27479539IPR009057Homeodomain-like
CDDcd000862.30E-11486538No hitNo description
PfamPF059204.9E-16494533IPR008422Homeobox KN domain
PROSITE patternPS000270512535IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 692 aa     Download sequence    Send to blast
MARRAWGMID LRLLNSGSLP FPRRDTNQQE RVRGRSQSLS EPRAPHIPRW PARSPPHARA  60
FPLPAHVLSS QGYSQCHNHR NNSLSRLELR GYYHPRQGYI LSRSLHCALP CPGFSGAKYH  120
TRPHASPPPP AERTSVGFSE ITGSRGSDNG RRARSLHQDI PGDPPTPMEE ITHHFGVGGS  180
GQGQQQHHHS WVSALGAVLA PQPSAGLPLT LNTVAAGNSG AHSGSSNPVL QLANGGSLLD  240
ACVKAKEPSS SSPYAGDVEA IKAKIISHPH YYSLLAAYLE CQKASPVGAP PEVSARLTAI  300
AQEVEARQRT SLVGLGSATE PELDQFMVSH FYRLINEAYH EMLVKFREEL TRPLQEAMEF  360
MRRVESQLNS LSISGRSLRR ILSSARVWER AHGTVQGRGV SLPISCAGWC GLPDALVHYA  420
YPAQRGTGSS EEDQEGSGGE TELPEVDAHG VDQELKHHLL KKYSGYLSSL KQELSKKKKK  480
GKLPKEARQQ LLNWWEMHYK WPYPSETQKG ALAESTGLDL KQINNWFINQ RKRHWKPSEE  540
MHHLMMDGYH APNAFYMDGH FLNEPGLYRF DRTCDAIDAP DAPRCGEVRI ARSMHGLPLW  600
VGILEEAAAA KLVDWTGRVR RAMELPAAVS RSPSRLQARV VQDSCPESRH DAEADAGPPP  660
RRSPAFYSSV FAQIEEIGWE RLVSSKGNDG IS
Functional Description ? help Back to Top
Source Description
UniProtBinds to RNA (PubMed:17965274). Possible transcription factor that regulates genes involved in development. Mutations in KN-1 alter leaf development. Foci of cells along the lateral vein do not differentiate properly but continue to divide, forming knots. May participate in the switch from indeterminate to determinate cell fates. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:17965274}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004981913.10.0homeotic protein knotted-1
SwissprotP243450.0KN1_MAIZE; Homeotic protein knotted-1
TrEMBLA0A0A9CTZ30.0A0A0A9CTZ3_ARUDO; Kn1
STRINGGRMZM2G017087_P020.0(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP98863145
Publications ? help Back to Top
  1. Lowe B,Mathern J,Hake S
    Active Mutator elements suppress the knotted phenotype and increase recombination at the Kn1-O tandem duplication.
    Genetics, 1992. 132(3): p. 813-22
    [PMID:1334895]
  2. Sinha N,Hake S
    Mutant characters of knotted maize leaves are determined in the innermost tissue layers.
    Dev. Biol., 1990. 141(1): p. 203-10
    [PMID:2391001]
  3. Chen H,Jackson D,Kim JY
    Identification of evolutionarily conserved amino acid residues in homeodomain of KNOX proteins for intercellular trafficking.
    Plant Signal Behav, 2014. 9(3): p. e28355
    [PMID:24603432]
  4. Sinha NR,Williams RE,Hake S
    Overexpression of the maize homeo box gene, KNOTTED-1, causes a switch from determinate to indeterminate cell fates.
    Genes Dev., 1993. 7(5): p. 787-95
    [PMID:7684007]
  5. Greene B,Walko R,Hake S
    Mutator insertions in an intron of the maize knotted1 gene result in dominant suppressible mutations.
    Genetics, 1994. 138(4): p. 1275-85
    [PMID:7896105]
  6. Mathern J,Hake S
    Mu element-generated gene conversions in maize attenuate the dominant knotted phenotype.
    Genetics, 1997. 147(1): p. 305-14
    [PMID:9286690]