PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Zoysieae; Zoysiinae; Zoysia

Family

TCP

Protein Properties

Length: 309aa MW: 30904.1 Da PI: 9.7507

Description

TCP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Zjn_sc00007.1.g04810.1.am.mk	genome	ZGD	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	TCP	128.8	5.5e-40	62	155	2	94
TCP 2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssss 81 ++k+++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++ + s +ss Zjn_sc00007.1.g04810.1.am.mk 62 PPKRSSTKDRHTKVEGRGRRIRMPALCAARVFQLTRELGHKTDGETIEWLLQQAEPAVIAATGTGTIPANFTsLNISLRSS 142 689******************************************************************999877777777 PP TCP 82 asnsssgkaaksa 94 +s+ s++++ ++a Zjn_sc00007.1.g04810.1.am.mk 143 GSSFSAPAHLRAA 155 7755555443333 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF03634	1.1E-38	67	155	IPR005333	Transcription factor, TCP
PROSITE profile	PS51369	27.861	68	122	IPR017887	Transcription factor TCP subgroup

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0007623	Biological Process	circadian rhythm
GO:0008283	Biological Process	cell proliferation
GO:0009735	Biological Process	response to cytokinin
GO:0010229	Biological Process	inflorescence development
GO:0010252	Biological Process	auxin homeostasis
GO:0031540	Biological Process	regulation of anthocyanin biosynthetic process
GO:0042023	Biological Process	DNA endoreduplication
GO:0048467	Biological Process	gynoecium development

Sequence ? help Back to Top
Protein Sequence Length: 309 aa Download sequence Send to blast
MDVAGDGGGG RRPNFPLQLL EKKEEQPCSS SAAVGASAGG GNGNGSGAPC GPGGEVQVRK 60 TPPKRSSTKD RHTKVEGRGR RIRMPALCAA RVFQLTRELG HKTDGETIEW LLQQAEPAVI 120 AATGTGTIPA NFTSLNISLR SSGSSFSAPA HLRAALPSPS SAVRFGRADA WDRVGGTPSS 180 GGGSGGNGGG SGESIWTFPQ MSSAAAAAAM YRGNVPSGLH FMNFPAAPMA LLPGQQLGLG 240 PVGGSGGGGD GGGGEGHMGI LTALNAYRTQ TATDSAATQQ GDGGGRGSGQ QQHGGGRGER 300 HESMSTSDS

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved the regulation of plant development. Together with TCP14, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in developing leaf blade and specific floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Involved in gynoecium and silique development. Modulates the development of the different tissues of the gynoecium through its participation in auxin and cytokinin responses. Modulates the expression of the cytokinin-responsive genes ARR7 and ARR15. May repress the expression of the auxin biosynthetic genes YUC1 and YUC4 (PubMed:26303297). Acts as negative regulator of anthocyanin accumulation under high light conditions. Modulates the expression of transcription factors involved in the induction of anthocyanin biosynthesis genes (PubMed:26574599). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). {ECO:0000269\|PubMed:21668538, ECO:0000269\|PubMed:22267487, ECO:0000269\|PubMed:24689742, ECO:0000269\|PubMed:25655823, ECO:0000269\|PubMed:25757472, ECO:0000269\|PubMed:26303297, ECO:0000269\|PubMed:26574599}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00224	DAP	Transfer from AT1G69690	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:21183706). Induced during seed imbibition (PubMed:25655823). Induced by cytokinin (PubMed:26303297). {ECO:0000269\|PubMed:21183706, ECO:0000269\|PubMed:25655823, ECO:0000269\|PubMed:26303297}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_025825808.1	1e-90	transcription factor TCP14-like
Swissprot	Q9C9L2	3e-54	TCP15_ARATH; Transcription factor TCP15
TrEMBL	B8AIH1	1e-115	B8AIH1_ORYSI; Uncharacterized protein
STRING	LPERR02G26560.1	1e-108	(Leersia perrieri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP3744	34	79

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69690.1	2e-46	TCP family protein

Publications ? help Back to Top
Steiner E, et al. The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin. Plant Physiol., 2016. 171(2): p. 1485-94 [PMID:27208284] Dong H, et al. Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis. Genes Dev., 2017. 31(2): p. 197-208 [PMID:28167503] Zhang N, et al. MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis. Plant J., 2018. 93(1): p. 66-78 [PMID:29086441] Mazur MJ, et al. Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci. Front Plant Sci, 2017. 8: p. 2043 [PMID:29250092]