PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Maloideae; Amygdaleae; Prunus

Family

C2H2

Protein Properties

Length: 613aa MW: 67053.7 Da PI: 8.6238

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016650372.1	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	16.9	1.8e-05	108	130	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H XP_016650372.1 108 FVCEICNKGFQRDQNLQLHRRGH 130 89*******************88 PP
2	zf-C2H2	15.3	5.8e-05	184	206	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ XP_016650372.1 184 WKCDKCSKKYAVQSDWKAHQKTC 206 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	7.28E-8	107	130	No hit	No description
Gene3D	G3DSA:3.30.160.60	2.1E-5	107	130	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.949	108	130	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.017	108	130	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	110	130	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	149	179	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	7.4E-5	172	205	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	7.28E-8	179	205	No hit	No description
SMART	SM00355	94	184	204	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 613 aa Download sequence Send to blast
MSNITGDVEE GSFSSGNNTG ELEVHQENQQ QNHLQGSGSG GASGAQSNSN GSVTQQQQQQ 60 QQQPPLKKKR NLPGTPGKYV CLISPFVAXX XAEVIALSPT TLMATNRFVC EICNKGFQRD 120 QNLQLHRRGH NLPWKLRQRT TTEIRKRVYI CPEPTCVHHN PARALGDLTG IKKHFSRKHG 180 EKKWKCDKCS KKYAVQSDWK AHQKTCGTRE YKCDCGTIFS RRDSFITHRA FCDALAEENN 240 KVNHGLMSSQ TQMPLPHDQL ISSMAMNTNS SMGGGSDVLN YDISNKNSIN KSFPDDLVPM 300 PFKSMNMNIM AGGVGGPGMF SSTSGSLFGG PRSVSSASAS SLQLSSNNNN SSSGFNYLHH 360 QETKNGGSTQ SNITGAAQMS ATALLQKAAQ MGATASNSTI NSPMMQKSFV SSMAGPDQLS 420 VNPISINNNN NNNNNNIRPP SSYDDHHHQF QQQQPPDHHQ PHNSHNMVVG GFTNQLMQKG 480 GPQEMSQLFD HHTNSAASSA MTDMGLYSQV FMGIGGDPHH HHEISAANNN SSPNSIHGIR 540 INAMERGAMG PSTTLDLLGI GGSRPPNLHE HQQQQQRLDL EAMSQHRLPA IMNPFQQQRS 600 HGDSAMEKQI WDV

Sequence ? help Back to Top

Protein Sequence Length: 613 aa Download sequence Send to blast

MSNITGDVEE GSFSSGNNTG ELEVHQENQQ QNHLQGSGSG GASGAQSNSN GSVTQQQQQQ  60
QQQPPLKKKR NLPGTPGKYV CLISPFVAXX XAEVIALSPT TLMATNRFVC EICNKGFQRD  120
QNLQLHRRGH NLPWKLRQRT TTEIRKRVYI CPEPTCVHHN PARALGDLTG IKKHFSRKHG  180
EKKWKCDKCS KKYAVQSDWK AHQKTCGTRE YKCDCGTIFS RRDSFITHRA FCDALAEENN  240
KVNHGLMSSQ TQMPLPHDQL ISSMAMNTNS SMGGGSDVLN YDISNKNSIN KSFPDDLVPM  300
PFKSMNMNIM AGGVGGPGMF SSTSGSLFGG PRSVSSASAS SLQLSSNNNN SSSGFNYLHH  360
QETKNGGSTQ SNITGAAQMS ATALLQKAAQ MGATASNSTI NSPMMQKSFV SSMAGPDQLS  420
VNPISINNNN NNNNNNIRPP SSYDDHHHQF QQQQPPDHHQ PHNSHNMVVG GFTNQLMQKG  480
GPQEMSQLFD HHTNSAASSA MTDMGLYSQV FMGIGGDPHH HHEISAANNN SSPNSIHGIR  540
INAMERGAMG PSTTLDLLGI GGSRPPNLHE HQQQQQRLDL EAMSQHRLPA IMNPFQQQRS  600
HGDSAMEKQI WDV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	4e-34	180	243	3	66	Zinc finger protein JACKDAW
5b3h_F	4e-34	180	243	3	66	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_016650372.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016650372.1	0.0	PREDICTED: zinc finger protein NUTCRACKER-like
Swissprot	Q9SCQ6	1e-108	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A251N5H5	0.0	A0A251N5H5_PRUPE; Uncharacterized protein
STRING	XP_008235084.1	0.0	(Prunus mume)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF2192	30	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-95	indeterminate(ID)-domain 2

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]