PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 347aa MW: 38280 Da PI: 8.7561

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016506501.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	104.8	4.7e-33	167	225	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 ldDg++WrKYGqK vk+s+fprsYYrCt+a+C vkk+vers+ed+++v++tYeg H+h+ XP_016506501.1 167 LDDGFRWRKYGQKAVKNSPFPRSYYRCTTATCGVKKRVERSSEDTSIVVTTYEGIHTHP 225 59********************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.2E-33	152	227	IPR003657	WRKY domain
SuperFamily	SSF118290	7.06E-29	159	227	IPR003657	WRKY domain
PROSITE profile	PS50811	30.71	162	227	IPR003657	WRKY domain
SMART	SM00774	4.2E-39	167	226	IPR003657	WRKY domain
Pfam	PF03106	4.8E-26	168	225	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 347 aa Download sequence Send to blast
MLLIKSMADK ENKLKPNTSS LEISTFSDQI PANNYSLSSI FDMPTCETEK GSSLSLIETM 60 FSSHPITTPS TFDLLQPPPP AVPLLVPSQI VNKIPSSEIV NTPNSSSISS SSTEAAANDD 120 QLQPNTQTVD GDDQHKNKKQ LKPKKKNQKR QREPRFAFMT KSEVDHLDDG FRWRKYGQKA 180 VKNSPFPRSY YRCTTATCGV KKRVERSSED TSIVVTTYEG IHTHPCPITP RSCIGILSET 240 TAYGGSIGGL GGNGGGSSLF IPQFHYQALQ QQPTYFQTPT LPMNFISTCD SSLYSSQERR 300 FSPSTSSSSS LARDHGLLQD MVPSQMRRDP KQEVAFSLST LSMKSQS

Sequence ? help Back to Top

Protein Sequence Length: 347 aa Download sequence Send to blast

MLLIKSMADK ENKLKPNTSS LEISTFSDQI PANNYSLSSI FDMPTCETEK GSSLSLIETM  60
FSSHPITTPS TFDLLQPPPP AVPLLVPSQI VNKIPSSEIV NTPNSSSISS SSTEAAANDD  120
QLQPNTQTVD GDDQHKNKKQ LKPKKKNQKR QREPRFAFMT KSEVDHLDDG FRWRKYGQKA  180
VKNSPFPRSY YRCTTATCGV KKRVERSSED TSIVVTTYEG IHTHPCPITP RSCIGILSET  240
TAYGGSIGGL GGNGGGSSLF IPQFHYQALQ QQPTYFQTPT LPMNFISTCD SSLYSSQERR  300
FSPSTSSSSS LARDHGLLQD MVPSQMRRDP KQEVAFSLST LSMKSQS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-25	160	227	10	77	Probable WRKY transcription factor 4
2lex_A	1e-25	160	227	10	77	Probable WRKY transcription factor 4
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016506501.1	0.0	PREDICTED: probable WRKY transcription factor 48 isoform X2
Swissprot	O22900	2e-53	WRK23_ARATH; WRKY transcription factor 23
TrEMBL	A0A1S4CZF3	0.0	A0A1S4CZF3_TOBAC; probable WRKY transcription factor 48 isoform X2
STRING	XP_009764098.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G49520.1	5e-51	WRKY DNA-binding protein 48

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guo D,Qin G EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signal Behav, 2016. 11(3): p. e1150404 [PMID:26914912] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885]