PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Protein Features |

Gene Ontology |

Function |

Regulation |

Publication

Basic Information? help Back to Top

TF ID

XP_016506450.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

MYB_related

Protein Properties

Length: 428aa MW: 46537.4 Da PI: 4.5581

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016506450.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	38.1	3.5e-12	188	231	2	47
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 WT E + l+++ +G + Wk++a+++g gR++k+c+ r+ k+ XP_016506450.1 188 TDWTDKETLHLLEVLMHYGDD-WKKVAEHVG-GRSAKECVARFVKL 231 57***************88.*****.********9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51293	19.59	185	236	IPR017884	SANT domain
SuperFamily	SSF46689	4.49E-13	186	240	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.6E-9	186	228	IPR009057	Homeodomain-like
SMART	SM00717	5.0E-10	186	234	IPR001005	SANT/Myb domain
Pfam	PF00249	4.7E-12	188	231	IPR001005	SANT/Myb domain
CDD	cd00167	1.03E-8	190	231	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 428 aa Download sequence Send to blast
MAETGDSKSP AANPNSETTS PPPPPPPPPP LQQPQHQPQT PSQPQLQPPP QTPSQPQPAP 60 QQPQTELLPP KCPQQLESSP NPTTPSATDS KDVTPTTLSS RLTEPDYIYI PSYSPPQNAD 120 ANGTTPTDFT APKKRLCSAC KSACSIACFV SDKYDLTLCA RCYVRGNFRV GMNTSDFRRV 180 EISEEVKTDW TDKETLHLLE VLMHYGDDWK KVAEHVGGRS AKECVARFVK LPFGEQFMGP 240 PVSAEVDNEP GSETILLPSK RMRLTPLADA SNPIMAQAAF LSALAGKEVA ELAAHAAVTA 300 LSDNGEGITK GSLGSLPGVL EKKESDGTSN GIAKDTLERA LVEARSQLEE EAQDLERAVS 360 DVAIEAKEIE DKIARFEERD LQMEKEWQQL MQLKNLIFFD QLTLLLNKVG SAKAGETIGE 420 EVMNVKAE

Sequence ? help Back to Top

Protein Sequence Length: 428 aa Download sequence Send to blast

MAETGDSKSP AANPNSETTS PPPPPPPPPP LQQPQHQPQT PSQPQLQPPP QTPSQPQPAP  60
QQPQTELLPP KCPQQLESSP NPTTPSATDS KDVTPTTLSS RLTEPDYIYI PSYSPPQNAD  120
ANGTTPTDFT APKKRLCSAC KSACSIACFV SDKYDLTLCA RCYVRGNFRV GMNTSDFRRV  180
EISEEVKTDW TDKETLHLLE VLMHYGDDWK KVAEHVGGRS AKECVARFVK LPFGEQFMGP  240
PVSAEVDNEP GSETILLPSK RMRLTPLADA SNPIMAQAAF LSALAGKEVA ELAAHAAVTA  300
LSDNGEGITK GSLGSLPGVL EKKESDGTSN GIAKDTLERA LVEARSQLEE EAQDLERAVS  360
DVAIEAKEIE DKIARFEERD LQMEKEWQQL MQLKNLIFFD QLTLLLNKVG SAKAGETIGE  420
EVMNVKAE

Functional Description ? help Back to Top
Source	Description
UniProt	Component of a multiprotein complex equivalent of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. May play an essential role in the transition from the vegetative to the reproductive phase of development. May be a positive regulator of ABA signaling. {ECO:0000269\|PubMed:12140326, ECO:0000269\|PubMed:14682613, ECO:0000269\|PubMed:16055636, ECO:0000269\|PubMed:19033529}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016506450.1	0.0	PREDICTED: SWI/SNF complex subunit SWI3B-like isoform X2
Swissprot	Q84JG2	3e-86	SWI3B_ARATH; SWI/SNF complex subunit SWI3B
TrEMBL	A0A1S4CZ61	0.0	A0A1S4CZ61_TOBAC; SWI/SNF complex subunit SWI3B-like isoform X2
STRING	XP_009624805.1	0.0	(Nicotiana tomentosiformis)

Publications ? help Back to Top
Sarnowski TJ,Swiezewski S,Pawlikowska K,Kaczanowski S,Jerzmanowski A AtSWI3B, an Arabidopsis homolog of SWI3, a core subunit of yeast Swi/Snf chromatin remodeling complex, interacts with FCA, a regulator of flowering time. Nucleic Acids Res., 2002. 30(15): p. 3412-21 [PMID:12140326] Zhou C,Miki B,Wu K CHB2, a member of the SWI3 gene family, is a global regulator in Arabidopsis. Plant Mol. Biol., 2003. 52(6): p. 1125-34 [PMID:14682613] Sarnowski TJ, et al. SWI3 subunits of putative SWI/SNF chromatin-remodeling complexes play distinct roles during Arabidopsis development. Plant Cell, 2005. 17(9): p. 2454-72 [PMID:16055636] Archacki R, et al. Genetic analysis of functional redundancy of BRM ATPase and ATSWI3C subunits of Arabidopsis SWI/SNF chromatin remodelling complexes. Planta, 2009. 229(6): p. 1281-92 [PMID:19301030] Zhu Y,Rowley MJ,Böhmdorfer G,Wierzbicki AT A SWI/SNF chromatin-remodeling complex acts in noncoding RNA-mediated transcriptional silencing. Mol. Cell, 2013. 49(2): p. 298-309 [PMID:23246435] Liu ZW, et al. Two Components of the RNA-Directed DNA Methylation Pathway Associate with MORC6 and Silence Loci Targeted by MORC6 in Arabidopsis. PLoS Genet., 2016. 12(5): p. e1006026 [PMID:27171427] Han W, et al. The SWI/SNF subunit SWI3B regulates IAMT1 expression via chromatin remodeling in Arabidopsis leaf development. Plant Sci., 2018. 271: p. 127-132 [PMID:29650150]