PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016503267.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 440aa MW: 49580.8 Da PI: 7.3093

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016503267.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.3	7.1e-07	193	214	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H XP_016503267.1 193 FCTICGKGFKRDANLRMHMRGH 214 6*******************98 PP
2	zf-C2H2	14.1	0.00013	312	327	6	21
TTEEESSHHHHHHHHH CS zf-C2H2 6 CgksFsrksnLkrHir 21 Cg++Fsrk+ L rHi+ XP_016503267.1 312 CGTTFSRKDKLFRHIS 327 **************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.05E-5	191	216	No hit	No description
SMART	SM00355	0.0026	192	214	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.03	192	219	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	4.2E-6	193	244	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	194	214	IPR007087	Zinc finger, C2H2
SMART	SM00355	180	242	275	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	33	280	302	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 440 aa Download sequence Send to blast
MEQQVNQRSE NHDFTRIQDW DPKAILKNMS FLEQKIHQLQ ELVRIIFDHR SLVGIQGNDL 60 SSQQQQLITA DLTSIIVQLI STAGSLLPTV KHHTFSSASP TTKQPAQFGG VSVPSEKGIN 120 AGALPHSVNV TKAEDQSNHV DLMGDCGIEQ KYAADEHEAN DEDEFHEEEN LPPGSYEILQ 180 LEKEEILAPH THFCTICGKG FKRDANLRMH MRGHGDEYKT PAALAQPHKD PSSRTMTLIK 240 RYSCPCVGCK RNKEHKRFQP LKTISCVKKH YRRTHCEKSY ACSRCNLKKF SVIADLRTHE 300 KHCGKDKWLC SCGTTFSRKD KLFRHISLFQ GHTPAIPLEE TKGFAETSDQ GHTGKATTEA 360 GGIGCELNVQ NGSGLQNTIN VKEDADNPGS YLSPLNIETS KLSELQEFPR PPFEDPENSF 420 SFLLSGSCNY PRRLEKYRFY

Sequence ? help Back to Top

Protein Sequence Length: 440 aa Download sequence Send to blast

MEQQVNQRSE NHDFTRIQDW DPKAILKNMS FLEQKIHQLQ ELVRIIFDHR SLVGIQGNDL  60
SSQQQQLITA DLTSIIVQLI STAGSLLPTV KHHTFSSASP TTKQPAQFGG VSVPSEKGIN  120
AGALPHSVNV TKAEDQSNHV DLMGDCGIEQ KYAADEHEAN DEDEFHEEEN LPPGSYEILQ  180
LEKEEILAPH THFCTICGKG FKRDANLRMH MRGHGDEYKT PAALAQPHKD PSSRTMTLIK  240
RYSCPCVGCK RNKEHKRFQP LKTISCVKKH YRRTHCEKSY ACSRCNLKKF SVIADLRTHE  300
KHCGKDKWLC SCGTTFSRKD KLFRHISLFQ GHTPAIPLEE TKGFAETSDQ GHTGKATTEA  360
GGIGCELNVQ NGSGLQNTIN VKEDADNPGS YLSPLNIETS KLSELQEFPR PPFEDPENSF  420
SFLLSGSCNY PRRLEKYRFY

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975445	0.0	HG975445.1 Solanum pennellii chromosome ch06, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016503267.1	0.0	PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Swissprot	Q9C8N5	1e-162	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A1S4CPT4	0.0	A0A1S4CPT4_TOBAC; protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
STRING	XP_009624046.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4754	24	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	1e-155	C2H2 family protein

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]