PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

MYB_related

Protein Properties

Length: 298aa MW: 33021.2 Da PI: 10.5592

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016501292.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	38.6	2.5e-12	5	55	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT.....TTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg.....kgRtlkqcksrwqk 46 +++WT+eE+ l+ +v+++G+g W+tI + R+ ++k++w++ XP_016501292.1 5 KQKWTPEEEAALKAGVRKHGPGKWRTILKDPEfsgvlCLRSNVDLKDKWRN 55 79*********************************66********99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	13.318	1	58	IPR017930	Myb domain
SuperFamily	SSF46689	5.81E-16	2	70	IPR009057	Homeodomain-like
SMART	SM00717	5.7E-8	4	59	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	7.2E-15	4	56	IPR009057	Homeodomain-like
Pfam	PF00249	1.6E-9	5	55	IPR001005	SANT/Myb domain
CDD	cd11660	2.86E-19	6	56	No hit	No description
SuperFamily	SSF46785	1.69E-17	118	197	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00526	7.2E-16	118	183	IPR005818	Linker histone H1/H5, domain H15
Gene3D	G3DSA:1.10.10.10	1.2E-15	119	189	IPR011991	Winged helix-turn-helix DNA-binding domain
PROSITE profile	PS51504	24.798	120	188	IPR005818	Linker histone H1/H5, domain H15
Pfam	PF00538	8.8E-9	125	181	IPR005818	Linker histone H1/H5, domain H15

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006334	Biological Process	nucleosome assembly
GO:0000786	Cellular Component	nucleosome
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 298 aa Download sequence Send to blast
MGAPKQKWTP EEEAALKAGV RKHGPGKWRT ILKDPEFSGV LCLRSNVDLK DKWRNMSVMA 60 NGWGSREKAR LALKRMNQTR KQDEKSLAVT IEAQSDEEIV EARLAITSSG SPQIGGSKRS 120 IIRLDNLIME AISNLKEPGG SNKTTIATYI EDQYWAPPNF KRLLSAKLKY LTATGRLIKV 180 KRKYRIAPMS ALSDRRRMPS IPLLESGQMI SNRVDMNMRT TKAQVDLELA MMRSMTLQEA 240 AAAAAQAVAE AEAAIEEAEE AARVAEAAEA EAEAAQAFAK AAMKTLQGRS FRRMMIRA

Functional Description ? help Back to Top
Source	Description
UniProt	Binds preferentially double-stranded telomeric repeats. {ECO:0000269\|PubMed:19102728}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC233135	1e-63	AC233135.4 Solanum lycopersicum strain Heinz 1706 chromosome 1 clone hba-92h13 map 1, complete sequence.
GenBank	HG975440	1e-63	HG975440.1 Solanum pennellii chromosome ch01, complete genome.
GenBank	HG975513	1e-63	HG975513.1 Solanum lycopersicum chromosome ch01, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016501292.1	0.0	PREDICTED: telomere repeat-binding factor 1-like
Refseq	XP_016501293.1	0.0	PREDICTED: telomere repeat-binding factor 1-like
Swissprot	Q8VWK4	1e-101	TRB1_ARATH; Telomere repeat-binding factor 1
TrEMBL	A0A1S4CJC8	0.0	A0A1S4CJC8_TOBAC; telomere repeat-binding factor 1-like
STRING	XP_009758805.1	1e-178	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2864	24	48

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G49950.3	5e-99	telomere repeat binding factor 1

Publications ? help Back to Top
Alexandrov NN, et al. Features of Arabidopsis genes and genome discovered using full-length cDNAs. Plant Mol. Biol., 2006. 60(1): p. 69-85 [PMID:16463100] Schrumpfová PP, et al. Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase. Plant J., 2014. 77(5): p. 770-81 [PMID:24397874] Liang SC, et al. Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet., 2015. 11(12): p. e1005660 [PMID:26642436] Fulcher N,Riha K Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana. Front Genet, 2015. 6: p. 349 [PMID:26779251] Kotliński M, et al. Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain. Plant Physiol., 2017. 174(1): p. 27-34 [PMID:28298478]