PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016500150.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 498aa    MW: 55209.7 Da    PI: 8.5039
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016500150.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.72.1e-0592114123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     ++C++C+k F r  nL+ H r H
  XP_016500150.1  92 FVCEICSKGFQRDQNLQLHRRGH 114
                     89*******************88 PP
2zf-C2H211.60.00089168190123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     +kC +C+k +  +s+ k H +t+
  XP_016500150.1 168 WKCDKCSKIYAVQSDWKAHSKTC 190
                     58*****************9998 PP
3zf-C2H212.60.00042198216523
                     TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   5 dCgksFsrksnLkrHirtH 23 
                     dCg++Fsrk+++++H   +
  XP_016500150.1 198 DCGTVFSRKDSFVTHRAFC 216
                     8**************8765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.605.9E-591114IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.87E-691114No hitNo description
SMARTSM003550.03692114IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015710.88792114IPR007087Zinc finger, C2H2
PROSITE patternPS00028094114IPR007087Zinc finger, C2H2
SMARTSM00355260133163IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.4E-4156189IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.87E-6163188No hitNo description
SMARTSM00355180168188IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 498 aa     Download sequence    Send to blast
MNQEKQIYHQ SNSGCFSLLE SSSVLSHQAA MFSDEASVSS TTRVPNLCPM PQTISNHQPQ  60
KIKKKRSLPG NPDPDAEVIV LSPKTLLATN RFVCEICSKG FQRDQNLQLH RRGHNLPWKL  120
KQRNNKENRK KAYVCPEPTC VHHHPSRALG DLTGIKKHYC RKHGEKKWKC DKCSKIYAVQ  180
SDWKAHSKTC GTREYRCDCG TVFSRKDSFV THRAFCDALA EESARLSANS ALMHRAAVAA  240
ATTESNFHLN QSSPIFFPFP TTNQRHFANP PPPPTTAVTT HISLNNPWDP QIPLNPNPTH  300
HEENHNQMTH HPVPIKTESI HIPISSSVPP FYQDHFFHKG SFANIPSPQL SATALLQKAA  360
TIGTTHSAVS HVNSTMAQLN RTSLGHMTHK ISPEDFLGFG SDNMSNTWQQ KSENLTRDFL  420
GLTGDHDHDE SCADGNGRNG GLFVTYGGGG VGNGNGGMDF QQTLYERDHS SVLKHHQLGF  480
GFAATATAET ASETWGNC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C7e-35164230369Zinc finger protein JACKDAW
5b3h_F7e-35164230369Zinc finger protein JACKDAW
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1118130KLKQRNNKENRKK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016500150.10.0PREDICTED: protein indeterminate-domain 12-like
SwissprotQ9ZWA61e-112IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A1S4CG490.0A0A1S4CG49_TOBAC; protein indeterminate-domain 12-like
STRINGXP_009593681.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10324350
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.11e-112C2H2 family protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]