PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

HD-ZIP

Protein Properties

Length: 293aa MW: 32981.2 Da PI: 6.4056

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016500102.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	57.2	2.8e-18	128	182	2	56
T--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS Homeobox 2 rkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 rk+ +++keq +Lee F+++++++ +++ L+k+l+L rqV vWFqNrRa+ k XP_016500102.1 128 RKKLRLSKEQAAVLEETFKEHNTLNPKQKLALSKQLNLRPRQVEVWFQNRRARTK 182 788899***********************************************98 PP
2	HD-ZIP_I/II	125.7	2.1e-40	128	217	1	91
HD-ZIP_I/II 1 ekkrrlskeqvklLEesFeeeekLeperKvelareLglqprqvavWFqnrRARtktkqlEkdyeaLkraydalkeenerLekeveeLreel 91 +kk+rlskeq+++LEe+F+e+++L+p++K +l+++L+l+prqv+vWFqnrRARtk+kq+E+d+e+L++++++l+een+rL+kev+eLr +l XP_016500102.1 128 RKKLRLSKEQAAVLEETFKEHNTLNPKQKLALSKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLRHCCENLTEENRRLQKEVTELR-AL 217 69*************************************************************************************9.55 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51257	5	1	19	No hit	No description
Pfam	PF04618	1.6E-17	4	104	IPR006712	HD-ZIP protein, N-terminal
Gene3D	G3DSA:1.10.10.60	3.1E-17	124	187	IPR009057	Homeodomain-like
PROSITE profile	PS50071	16.925	124	184	IPR001356	Homeobox domain
SMART	SM00389	6.6E-15	126	188	IPR001356	Homeobox domain
SuperFamily	SSF46689	3.85E-18	127	194	IPR009057	Homeodomain-like
Pfam	PF00046	9.7E-16	128	182	IPR001356	Homeobox domain
CDD	cd00086	6.14E-15	128	185	No hit	No description
PROSITE pattern	PS00027	0	159	182	IPR017970	Homeobox, conserved site
SMART	SM00340	1.4E-24	184	227	IPR003106	Leucine zipper, homeobox-associated
Pfam	PF02183	1.8E-10	184	218	IPR003106	Leucine zipper, homeobox-associated

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 293 aa Download sequence Send to blast
MGGEKEDGLG LSLSLGMSCP QNNLKNNDFI SPSTPPFLLP FMHNHQISAE RNEEAREFIR 60 GEIDMNRPVR MIEACDEELE DEAVIMVSSP NNSTVSSVSG KRSHDREDNE GERPTSSLED 120 DGGDAAARKK LRLSKEQAAV LEETFKEHNT LNPKQKLALS KQLNLRPRQV EVWFQNRRAR 180 TKLKQTEVDC EYLRHCCENL TEENRRLQKE VTELRALKLS PQMYMNMTPP TTLTMCPQCE 240 RVAVSSSSSS VTSAGVSRSN HPVGALHQPP VPLNKPWAAI FSPKTLDDQR TQL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	176	184	RRARTKLKQ

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By transition from light to far-red light. {ECO:0000269\|PubMed:8106086}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016500102.1	0.0	PREDICTED: homeobox-leucine zipper protein HAT3-like
Swissprot	P92953	1e-82	ATHB4_ARATH; Homeobox-leucine zipper protein ATHB-4
TrEMBL	A0A1S4CFZ4	0.0	A0A1S4CFZ4_TOBAC; homeobox-leucine zipper protein HAT3-like
STRING	XP_009764264.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1118	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60390.1	3e-76	homeobox-leucine zipper protein 3

Publications ? help Back to Top
Carabelli M,Turchi L,Ruzza V,Morelli G,Ruberti I Homeodomain-Leucine Zipper II family of transcription factors to the limelight: central regulators of plant development. Plant Signal Behav, 2014. [PMID:23838958] Francisco M, et al. Genome Wide Association Mapping in Arabidopsis thaliana Identifies Novel Genes Involved in Linking Allyl Glucosinolate to Altered Biomass and Defense. Front Plant Sci, 2016. 7: p. 1010 [PMID:27462337] Gallemí M, et al. A non-DNA-binding activity for the ATHB4 transcription factor in the control of vegetation proximity. New Phytol., 2017. 216(3): p. 798-813 [PMID:28805249]