PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016493993.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 176aa    MW: 20146.3 Da    PI: 9.5468
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016493993.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH27.84.6e-091964452
                    HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHH CS
             HLH  4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIk 52
                    ++  rE+ RRdr+N++f eL ++l +    + +K +K++iL  A + + 
  XP_016493993.1 19 SKASREKLRRDRLNERFLELSSVLDPG---RPPKTEKVAILSDAQKMLI 64
                    6778**********************8...88**********9988765 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088812.5121566IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.92E-61871No hitNo description
PfamPF000101.8E-61965IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.13E-121990IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.5E-112088IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003532.7E-72172IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 176 aa     Download sequence    Send to blast
MCFNFIYRSR IECCSSPRSK ASREKLRRDR LNERFLELSS VLDPGRPPKT EKVAILSDAQ  60
KMLIELRTET QKLKESNEEL QEKIKELKAE KIELRDEKQR LKEEKENLEQ QVKTLASKPG  120
FLSHPSAMGA AFTAQGQVAG NKLMPFIGYP SVAMWQFMQP AVVDTSQDHV LRPPVA
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269|PubMed:17028341}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754461e-115HG975446.1 Solanum pennellii chromosome ch07, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016493993.11e-128PREDICTED: transcription factor ILR3-like
SwissprotQ9FH373e-72ILR3_ARATH; Transcription factor ILR3
TrEMBLA0A1S4BYT21e-126A0A1S4BYT2_TOBAC; transcription factor ILR3-like
STRINGXP_009764628.11e-120(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA9502482
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G54680.11e-63bHLH family protein
Publications ? help Back to Top
  1. Li X,Zhang H,Ai Q,Liang G,Yu D
    Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana.
    Plant Physiol., 2016. 170(4): p. 2478-93
    [PMID:26921305]
  2. Aparicio F,Pallás V
    The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response.
    Mol. Plant Pathol., 2017. 18(2): p. 173-186
    [PMID:26929142]
  3. Liang G,Zhang H,Li X,Ai Q,Yu D
    bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana.
    J. Exp. Bot., 2017. 68(7): p. 1743-1755
    [PMID:28369511]
  4. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]
  7. Samira R, et al.
    The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis.
    Plant Mol. Biol., 2018. 97(4-5): p. 297-309
    [PMID:29882068]