PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016483048.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 181aa MW: 20380.5 Da PI: 10.1222

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016483048.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.6	0.0004	47	69	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C+ C+k+F++ L H +H XP_016483048.1 47 FECKTCNKRFPSFQALGGHRASH 69 89**********99999998887 PP
2	zf-C2H2	14.4	0.00011	91	113	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++Cg+ Fs L H+r+H XP_016483048.1 91 HECSICGMEFSLGQALGGHMRRH 113 78********************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF13912	4.7E-13	47	71	IPR007087	Zinc finger, C2H2
SuperFamily	SSF57667	3.32E-9	47	113	No hit	No description
PROSITE profile	PS50157	10.118	47	74	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.075	47	69	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	49	69	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	3.6E-4	88	114	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profile	PS50157	10.118	91	118	IPR007087	Zinc finger, C2H2
Pfam	PF13912	1.3E-9	91	116	IPR007087	Zinc finger, C2H2
SMART	SM00355	0.067	91	113	IPR015880	Zinc finger, C2H2-like
PROSITE pattern	PS00028	0	93	113	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 181 aa Download sequence Send to blast
MTGIKRSREE DMQVEAEAMA NCALMLLSRL NNNNNATSTD RDYHNDFECK TCNKRFPSFQ 60 ALGGHRASHK RPKLLAGAGE FLVQSKKNKM HECSICGMEF SLGQALGGHM RRHRDEINKT 120 SVAAGNTMIP VARKKMIPVL KKSNSSKRIF CLDLNLSPDE NVDLKLWPTA PVSSPVLRWF 180 F

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor involved in light acclimation, cold and oxidative stress responses. May regulate a collection of transcripts involved in response to high-light, cold and oxidative stress. {ECO:0000269\|PubMed:11069694, ECO:0000269\|PubMed:14722088, ECO:0000269\|PubMed:15634197, ECO:0000269\|PubMed:16183833}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By H(2)O(2), cold, drought, cold or heat stresses, wounding, cucumber mosaic virus (CMV), exposure to high-intensity light and low-oxygen conditions in roots. {ECO:0000269\|PubMed:12368499, ECO:0000269\|PubMed:14722088, ECO:0000269\|PubMed:15634197, ECO:0000269\|PubMed:16183833, ECO:0000269\|PubMed:18201973, ECO:0000269\|PubMed:18922600}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016483048.1	1e-134	PREDICTED: zinc finger protein ZAT12-like
Swissprot	Q42410	2e-36	ZAT12_ARATH; Zinc finger protein ZAT12
TrEMBL	A0A1S4B2N5	1e-133	A0A1S4B2N5_TOBAC; zinc finger protein ZAT12-like
STRING	XP_009608410.1	1e-133	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA366	24	150

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G37430.1	7e-38	C2H2 family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Shi H,Chan Z The cysteine2/histidine2-type transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activated C-REPEAT-BINDING FACTOR pathway is essential for melatonin-mediated freezing stress resistance in Arabidopsis. J. Pineal Res., 2014. 57(2): p. 185-91 [PMID:24962049] Munekage YN,Inoue S,Yoneda Y,Yokota A Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana. Plant Cell Environ., 2015. 38(6): p. 1116-26 [PMID:25293694] Le CT, et al. ZINC FINGER OF ARABIDOPSIS THALIANA12 (ZAT12) Interacts with FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR (FIT) Linking Iron Deficiency and Oxidative Stress Responses. Plant Physiol., 2016. 170(1): p. 540-57 [PMID:26556796] Ben Daniel BH, et al. Identification of novel transcriptional regulators of Zat12 using comprehensive yeast one-hybrid screens. Physiol Plant, 2016. 157(4): p. 422-41 [PMID:26923089] Tang Y, et al. Oxidative stress-induced toxicity of CuO nanoparticles and related toxicogenomic responses in Arabidopsis thaliana. Environ. Pollut., 2016. 212: p. 605-614 [PMID:27016889] Corrales AR, et al. Multifaceted role of cycling DOF factor 3 (CDF3) in the regulation of flowering time and abiotic stress responses in Arabidopsis. Plant Cell Environ., 2017. 40(5): p. 748-764 [PMID:28044345] Xu J,Tran T,Padilla Marcia CS,Braun DM,Goggin FL Superoxide-responsive gene expression in Arabidopsis thaliana and Zea mays. Plant Physiol. Biochem., 2017. 117: p. 51-60 [PMID:28587993] Nguyen HM, et al. Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice. Front Plant Sci, 2017. 8: p. 1001 [PMID:28717360]