PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016478076.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

CAMTA

Protein Properties

Length: 1103aa MW: 123690 Da PI: 6.0312

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016478076.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	182.4	5.2e-57	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqr 96 l+ ++rwl++ ei++iL+n++k++++ e+++rp+sgsl+L++rk++ryfrkDG+sw+kkkdgktv+E+he+LK g+++vl+cyYah+een++fqr XP_016478076.1 20 LEAQHRWLRPAEICEILKNYQKFRIAPEPPNRPPSGSLFLFDRKVLRYFRKDGHSWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEENENFQR 114 5679***************************************************************************************** PP CG-1 97 rcywlLeeelekivlvhylevk 118 r+yw+Leee+++ivlvhy+evk XP_016478076.1 115 RSYWMLEEEMSHIVLVHYREVK 136 *****************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	83.558	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	1.9E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	3.7E-50	21	134	IPR005559	CG-1 DNA-binding domain
Gene3D	G3DSA:2.60.40.10	5.3E-4	517	600	IPR013783	Immunoglobulin-like fold
SuperFamily	SSF81296	9.57E-16	518	602	IPR014756	Immunoglobulin E-set
Pfam	PF01833	4.6E-4	518	594	IPR002909	IPT domain
PROSITE profile	PS50297	17.582	700	822	IPR020683	Ankyrin repeat-containing domain
CDD	cd00204	4.76E-12	700	809	No hit	No description
Gene3D	G3DSA:1.25.40.20	1.8E-17	701	814	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	1.48E-16	705	812	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	6.8E-8	722	813	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	1.9	750	780	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	8.576	750	783	IPR002110	Ankyrin repeat
SMART	SM00248	120	790	819	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	3.45E-7	919	976	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	50	925	947	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.346	927	955	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.18	928	946	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0042	948	970	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.285	949	973	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	5.0E-4	951	970	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009409	Biological Process	response to cold
GO:0010150	Biological Process	leaf senescence
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005516	Molecular Function	calmodulin binding

Sequence ? help Back to Top
Protein Sequence Length: 1103 aa Download sequence Send to blast
MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF 60 DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML 120 EEEMSHIVLV HYREVKGNRT NFSRTREPQE ATPRFQETDE DVHSSEVDSS ASTKFYPNGY 180 QVNSQVTDAT SLSSAQASEY EDAESAYNQH PTSGFHSFLD AQPSMMQKAG ESLPVPYHPI 240 PFSTDDHQVQ FAGSSDMDFF SSAPGNKSRN TANTYIPSRN LDFPSWETIS VNNPAAYQSY 300 HFQPSSQSGA NNMTHEQGST TMGQVFLNDF KKQGQNRIDS LGDWQTSEGD AAFISKWSMD 360 QKLNPNLASD HTIRSSAAYN VELHNSLEAS HILPSHQDKH PMQNELPSQL SDANVGGSLN 420 AELDHNLSIG VRTDHSSLKQ PLLDGVLREG LKKLDSFDRW MSKELEDVSE PHMQSNSSSY 480 WDNVGDDDGV DNSTIASQVQ LDTYMLSPSL SQDQFFSIID FSPSWAFAGS EIKVLITGKF 540 LKSQPEVEKW ACMFGELEVP AEVIADGVLR CHTPNQKVGR VPFYITCSNR LACSEVREFE 600 FRVSESQDVD VANSCSSSES LLHMRFGKLL SLESTVSLSS PPRSEDDVSN VCSKINSLLK 660 EDDNEWEEML NLTYENNFMA EKVKDQLLQK LLKEKLRVWL LQKVAEGGKG PNVLDEGGQG 720 VLHFAAALGY DWAIPPTIAA GVSVNFRDVN GWTALHWAAS YGRERTVGFL IISLGAAPGA 780 LTDPTPKHPS GRTPADLASS NGHKGIAGYL AESSLSSHLS SLELKEMKQG ETVQPFGEAV 840 QTVSERSATP AWDGDWPHGV SLKDSLAAVR NATQAAARIH QVFRVQSFQR KQLKEHGGSE 900 FGLSDEHALS LLALKTNKAG QHDEPVHTAA VRIQNKFRSW KGRRDYLLIR QRIIKIQAHV 960 RGHQVRNKYK NIIWSVGILE KVILRWRRKG SGLRGFKPEA TLTEGSNMQD RPVQEDDYDF 1020 LKEGRKQTEQ RLQKALARVK SMVQYPEARD QYRRLLNVVS DMKDTTTTSD GAPSNSGEAA 1080 DFGDDLIDLD DLLDDDTFMS TAP

Sequence ? help Back to Top

Protein Sequence Length: 1103 aa Download sequence Send to blast

MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF  60
DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML  120
EEEMSHIVLV HYREVKGNRT NFSRTREPQE ATPRFQETDE DVHSSEVDSS ASTKFYPNGY  180
QVNSQVTDAT SLSSAQASEY EDAESAYNQH PTSGFHSFLD AQPSMMQKAG ESLPVPYHPI  240
PFSTDDHQVQ FAGSSDMDFF SSAPGNKSRN TANTYIPSRN LDFPSWETIS VNNPAAYQSY  300
HFQPSSQSGA NNMTHEQGST TMGQVFLNDF KKQGQNRIDS LGDWQTSEGD AAFISKWSMD  360
QKLNPNLASD HTIRSSAAYN VELHNSLEAS HILPSHQDKH PMQNELPSQL SDANVGGSLN  420
AELDHNLSIG VRTDHSSLKQ PLLDGVLREG LKKLDSFDRW MSKELEDVSE PHMQSNSSSY  480
WDNVGDDDGV DNSTIASQVQ LDTYMLSPSL SQDQFFSIID FSPSWAFAGS EIKVLITGKF  540
LKSQPEVEKW ACMFGELEVP AEVIADGVLR CHTPNQKVGR VPFYITCSNR LACSEVREFE  600
FRVSESQDVD VANSCSSSES LLHMRFGKLL SLESTVSLSS PPRSEDDVSN VCSKINSLLK  660
EDDNEWEEML NLTYENNFMA EKVKDQLLQK LLKEKLRVWL LQKVAEGGKG PNVLDEGGQG  720
VLHFAAALGY DWAIPPTIAA GVSVNFRDVN GWTALHWAAS YGRERTVGFL IISLGAAPGA  780
LTDPTPKHPS GRTPADLASS NGHKGIAGYL AESSLSSHLS SLELKEMKQG ETVQPFGEAV  840
QTVSERSATP AWDGDWPHGV SLKDSLAAVR NATQAAARIH QVFRVQSFQR KQLKEHGGSE  900
FGLSDEHALS LLALKTNKAG QHDEPVHTAA VRIQNKFRSW KGRRDYLLIR QRIIKIQAHV  960
RGHQVRNKYK NIIWSVGILE KVILRWRRKG SGLRGFKPEA TLTEGSNMQD RPVQEDDYDF  1020
LKEGRKQTEQ RLQKALARVK SMVQYPEARD QYRRLLNVVS DMKDTTTTSD GAPSNSGEAA  1080
DFGDDLIDLD DLLDDDTFMS TAP

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00042	PBM	Transfer from AT2G22300	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF253511	0.0	AF253511.1 Nicotiana tabacum anther ethylene-upregulated protein ER1 (ER1) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009763882.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like isoform X1
Refseq	XP_016478076.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like isoform X1
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A1S4AN37	0.0	A0A1S4AN37_TOBAC; calmodulin-binding transcription activator 3-like isoform X1
TrEMBL	A0A1U7V6U6	0.0	A0A1U7V6U6_NICSY; calmodulin-binding transcription activator 3-like isoform X1
STRING	XP_009763882.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2230	21	46

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]