PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016471986.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 468aa    MW: 51997.1 Da    PI: 9.1921
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016471986.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.74.2e-055373323
                    ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                    C++Cgk F r  nL+ H r H
  XP_016471986.1 53 CEICGKGFQRDQNLQLHRRGH 73
                    *******************88 PP
2zf-C2H213.50.00021127149123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     +kC++C+k++  +s+ k H +t+
  XP_016471986.1 127 WKCEKCSKRYAVQSDWKAHSKTC 149
                     58*****************9998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576673.23E-65073No hitNo description
Gene3DG3DSA:3.30.160.604.0E-55073IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0765173IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.4895173IPR007087Zinc finger, C2H2
PROSITE patternPS0002805373IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.605.3E-5115148IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.23E-6122147No hitNo description
SMARTSM00355130127147IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 468 aa     Download sequence    Send to blast
MTEEVISSGF NSIEGSNPLP LKKKRNLPGN PDPEAEVIAL SPKTLMATNR FLCEICGKGF  60
QRDQNLQLHR RGHNLPWKLK QRTSKEVRKR VYVCPEKSCV HHHASRALGD LTGIKKHYCR  120
KHGEKKWKCE KCSKRYAVQS DWKAHSKTCG TREYRCDCGT IFSRRDSFVT HRAFCDALAE  180
ETARVTAASN MHNLLAGNNI NYHFIGSPLG PNMSQHFSSL FKPISTNNEN SDPIMRRDQL  240
SLWNMGQVSQ QQETIGNNNL QEIHQISPLI QTSTAAVYDT NTLLAPRSNP PPVNYNHVNW  300
EQLTNTSSAN TTVPSLFSNQ HQSHQQISPS STASMSATAL LQKAAQIGST TTTTDPSFLG  360
NNFGMNNCNG KNNNVQVQEV NNNKFCGFYV TTTNNSISTS LGSDVDQGSV NEFSTLNQLQ  420
MYNPPSKRRH IQTREDSVTG GGVGGQTRDF LGVGVQSICH PSSINGWI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C1e-35123190370Zinc finger protein JACKDAW
5b3h_F1e-35123190370Zinc finger protein JACKDAW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00125DAPTransfer from AT1G03840Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754461e-128HG975446.1 Solanum pennellii chromosome ch07, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016471986.10.0PREDICTED: zinc finger protein MAGPIE-like
SwissprotQ9ZWA61e-154IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A1S4A5Z10.0A0A1S4A5Z1_TOBAC; zinc finger protein MAGPIE-like
STRINGXP_009587634.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10324350
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.11e-147C2H2 family protein
Publications ? help Back to Top
  1. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]