PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016467050.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 230aa    MW: 25034.8 Da    PI: 9.0153
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016467050.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.90.0001691113123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     ykC+ CgksF +   L  H  +H
  XP_016467050.1  91 YKCSVCGKSFGSYQALGGHKASH 113
                     9*********9999998888777 PP
2zf-C2H213.40.00023147169123
                     EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                     ++C+ C+k+F++   L  H r+H
  XP_016467050.1 147 HECSVCHKTFPTGQALGGHKRRH 169
                     78*******************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576678.56E-990113No hitNo description
PfamPF139127.2E-1491116IPR007087Zinc finger, C2H2
PROSITE profilePS5015710.67991118IPR007087Zinc finger, C2H2
SMARTSM003550.005891113IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.9E-491113IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028093113IPR007087Zinc finger, C2H2
SuperFamilySSF576678.56E-9142169No hitNo description
PfamPF139122.8E-13146171IPR007087Zinc finger, C2H2
PROSITE profilePS501579.868147174IPR007087Zinc finger, C2H2
SMARTSM003550.043147169IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280149169IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006979Biological Processresponse to oxidative stress
GO:0009409Biological Processresponse to cold
GO:0009414Biological Processresponse to water deprivation
GO:0009611Biological Processresponse to wounding
GO:0009644Biological Processresponse to high light intensity
GO:0009651Biological Processresponse to salt stress
GO:0009737Biological Processresponse to abscisic acid
GO:0010117Biological Processphotoprotection
GO:0010200Biological Processresponse to chitin
GO:0015979Biological Processphotosynthesis
GO:0035264Biological Processmulticellular organism growth
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 230 aa     Download sequence    Send to blast
MALEALNSPR APTPPSFQYE NTTLNCLESW TKGKRSKRPR TIMEQQPTEE EYLAFCLLML  60
ARSNGNYTTS TKNQQPPQQI STLTSDSKNL YKCSVCGKSF GSYQALGGHK ASHRKQLING  120
DVNENSATTS TITAGATSAT GGSGRTHECS VCHKTFPTGQ ALGGHKRRHY EGKVTSSDGV  180
GSSSSQRGFD LNIPPLPEFW PGFGSGEDEV ESPHPAKKSR QFPSTKLELF
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor involved in abiotic stress responses. Can repress the stress responsive genes DREB1A and LTI78. Probably involved in jasmonate (JA) early signaling response. May regulate the expression of the JA biosynthesis gene LOX3 and control the expression of TIFY10A/JAZ1, a key repressor in the JA signaling cascade. {ECO:0000269|PubMed:12032082, ECO:0000269|PubMed:15333755, ECO:0000269|PubMed:17112521, ECO:0000269|PubMed:18216250, ECO:0000269|PubMed:20140232, ECO:0000269|PubMed:8662738}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00162DAPTransfer from AT1G27730Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By salt, cold and drought stresses. Down-regulated by gibberellin. {ECO:0000269|PubMed:10806347, ECO:0000269|PubMed:11351099, ECO:0000269|PubMed:12837949, ECO:0000269|PubMed:15333755, ECO:0000269|PubMed:17112521, ECO:0000269|PubMed:8662738}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016467050.11e-172PREDICTED: zinc finger protein ZAT10-like
SwissprotQ962892e-64ZAT10_ARATH; Zinc finger protein ZAT10
TrEMBLA0A1S3ZR961e-170A0A1S3ZR96_TOBAC; zinc finger protein ZAT10-like
STRINGXP_009630807.11e-171(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA7352495
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G27730.18e-59salt tolerance zinc finger
Publications ? help Back to Top
  1. Li C,Chang PP,Ghebremariam KM,Qin L,Liang Y
    Overexpression of tomato SpMPK3 gene in Arabidopsis enhances the osmotic tolerance.
    Biochem. Biophys. Res. Commun., 2014. 443(2): p. 357-62
    [PMID:24275141]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Shi H,Chan Z
    The cysteine2/histidine2-type transcription factor ZINC FINGER OF ARABIDOPSIS THALIANA 6-activated C-REPEAT-BINDING FACTOR pathway is essential for melatonin-mediated freezing stress resistance in Arabidopsis.
    J. Pineal Res., 2014. 57(2): p. 185-91
    [PMID:24962049]
  4. Munekage YN,Inoue S,Yoneda Y,Yokota A
    Distinct palisade tissue development processes promoted by leaf autonomous signalling and long-distance signalling in Arabidopsis thaliana.
    Plant Cell Environ., 2015. 38(6): p. 1116-26
    [PMID:25293694]
  5. van Buer J,Cvetkovic J,Baier M
    Cold regulation of plastid ascorbate peroxidases serves as a priming hub controlling ROS signaling in Arabidopsis thaliana.
    BMC Plant Biol., 2016. 16(1): p. 163
    [PMID:27439459]
  6. Corrales AR, et al.
    Multifaceted role of cycling DOF factor 3 (CDF3) in the regulation of flowering time and abiotic stress responses in Arabidopsis.
    Plant Cell Environ., 2017. 40(5): p. 748-764
    [PMID:28044345]
  7. Nguyen HM, et al.
    Ethanol Enhances High-Salinity Stress Tolerance by Detoxifying Reactive Oxygen Species in Arabidopsis thaliana and Rice.
    Front Plant Sci, 2017. 8: p. 1001
    [PMID:28717360]
  8. Geilen K,Heilmann M,Hillmer S,Böhmer M
    WRKY43 regulates polyunsaturated fatty acid content and seed germination under unfavourable growth conditions.
    Sci Rep, 2017. 7(1): p. 14235
    [PMID:29079824]
  9. Liu X, et al.
    Histone Deacetylase AtSRT1 Links Metabolic Flux and Stress Response in Arabidopsis.
    Mol Plant, 2017. 10(12): p. 1510-1522
    [PMID:29107034]
  10. Huang K, et al.
    Arabidopsis calcium-dependent protein kinase AtCPK1 plays a positive role in salt/drought-stress response.
    Biochem. Biophys. Res. Commun., 2018. 498(1): p. 92-98
    [PMID:29196259]