PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 309aa MW: 33376.6 Da PI: 5.4473

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016465866.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	104.6	5.2e-33	164	221	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+WrKYGqK vk+s+fprsYYrCt ++C+vkk+vers+edp++v++tYeg+H h+ XP_016465866.1 164 EDGYRWRKYGQKAVKNSPFPRSYYRCTNTKCTVKKRVERSSEDPSIVITTYEGQHCHH 221 8******************************************************997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	6.1E-34	148	222	IPR003657	WRKY domain
SuperFamily	SSF118290	1.83E-28	155	221	IPR003657	WRKY domain
PROSITE profile	PS50811	29.643	158	223	IPR003657	WRKY domain
SMART	SM00774	4.5E-39	163	222	IPR003657	WRKY domain
Pfam	PF03106	6.5E-26	164	221	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009414	Biological Process	response to water deprivation
GO:0009651	Biological Process	response to salt stress
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 309 aa Download sequence Send to blast
MDDKDKVDDP LKSAAEFDAT ESSWSLGADS NNVYSFFGNI DRDSSILNEF GWNFPPSEAA 60 GDKDVSGGSG GAGGFDRIDD DLAGNSSTTP SASATEVPAT GKITDEPVSS SCSDDPTEKS 120 TASGGSSASR PPSDTASKVK KKGQKRIRQP RFAFMTKSEV DHLEDGYRWR KYGQKAVKNS 180 PFPRSYYRCT NTKCTVKKRV ERSSEDPSIV ITTYEGQHCH HTVGFPRGGL ISHEAAFTTH 240 QLSPLASQFY LPGGVQYPQE VPMSAPESRQ IPGESAEARR LPETSQPANQ LPTDEGLLGD 300 IVPPGMRSR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	1e-25	153	220	7	74	Probable WRKY transcription factor 4
2lex_A	1e-25	153	220	7	74	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00067	PBM	Transfer from AT1G69310	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016465866.1	0.0	PREDICTED: probable WRKY transcription factor 57
Refseq	XP_016465867.1	0.0	PREDICTED: probable WRKY transcription factor 57
Refseq	XP_016465868.1	0.0	PREDICTED: probable WRKY transcription factor 57
Swissprot	Q9C983	4e-72	WRK57_ARATH; Probable WRKY transcription factor 57
TrEMBL	A0A1S3ZND3	0.0	A0A1S3ZND3_TOBAC; probable WRKY transcription factor 57
STRING	XP_009610330.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA8031	22	28

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G69310.2	9e-69	WRKY DNA-binding protein 57

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Jiang Y,Qiu Y,Hu Y,Yu D Heterologous Expression of AtWRKY57 Confers Drought Tolerance in Oryza sativa. Front Plant Sci, 2016. 7: p. 145 [PMID:26904091] Jiang Y,Yu D The WRKY57 Transcription Factor Affects the Expression of Jasmonate ZIM-Domain Genes Transcriptionally to Compromise Botrytis cinerea Resistance. Plant Physiol., 2016. 171(4): p. 2771-82 [PMID:27268959] Huang KC,Lin WC,Cheng WH Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis. BMC Plant Biol., 2018. 18(1): p. 40 [PMID:29490615]