PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 334aa MW: 37602.2 Da PI: 6.7213

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016463359.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	103.4	1.3e-32	178	235	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 +Dgy+WrKYGqK+vk+s fpr+YYrCtsa+C+vkk+ver+ +dp++v++tYeg+H+h+ XP_016463359.1 178 EDGYRWRKYGQKTVKNSSFPRNYYRCTSASCNVKKRVERCFNDPSIVVTTYEGKHTHP 235 8********************************************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.0E-35	162	237	IPR003657	WRKY domain
SuperFamily	SSF118290	2.88E-29	169	237	IPR003657	WRKY domain
PROSITE profile	PS50811	30.871	172	237	IPR003657	WRKY domain
SMART	SM00774	3.4E-38	177	236	IPR003657	WRKY domain
Pfam	PF03106	1.2E-25	178	235	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 334 aa Download sequence Send to blast
MESYRDIAIK MEDPMSYFDN FPVISNSFTG LVSDYNFAVE GKNNSINSSL GFMELLGVQD 60 FSSASVFDVT NLDKLLPKEE KYHIEPAVST AADESQNKLT VAADHESSNI LNTPSTPNSS 120 SISSETNEGH AQDAEGEVAE KEQTKTKQQL KAKKTVSQKK KREPRIAFMT KSEVDFLEDG 180 YRWRKYGQKT VKNSSFPRNY YRCTSASCNV KKRVERCFND PSIVVTTYEG KHTHPSPMNM 240 NMINMPRPTL FPTRVFPSPA PTATFPLQMP FPINQFAQPH FNDLTTSLAS NLDHAALVAH 300 GRRFCSTPSA AEIMRDQGFL QDLMSSRVVE EDYR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wj2_A	3e-26	170	237	10	77	Probable WRKY transcription factor 4
2lex_A	3e-26	170	237	10	77	Probable WRKY transcription factor 4
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	EU056916	9e-96	EU056916.1 Solanum tuberosum WRKY transcription factor 4 mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016463359.1	0.0	PREDICTED: probable WRKY transcription factor 68 isoform X2
Swissprot	O22900	2e-47	WRK23_ARATH; WRKY transcription factor 23
TrEMBL	A0A1S3ZG82	0.0	A0A1S3ZG82_TOBAC; probable WRKY transcription factor 68 isoform X2
STRING	XP_009789114.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G47260.1	4e-42	WRKY DNA-binding protein 23

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Guo D,Qin G EXB1/WRKY71 transcription factor regulates both shoot branching and responses to abiotic stresses. Plant Signal Behav, 2016. 11(3): p. e1150404 [PMID:26914912] Prát T, et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity. PLoS Genet., 2018. 14(1): p. e1007177 [PMID:29377885]