PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016459438.1
Common NameHD2c
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 268aa    MW: 29095.6 Da    PI: 4.4501
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016459438.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.30.00052243264323
                     ETTTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   3 CpdCgksFsrksnLkrHirt.H 23 
                     C+ C+++F +   L++H +  H
  XP_016459438.1 243 CKTCSRTFGSETALESHSKAkH 264
                     *****************88777 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5015710.596241268IPR007087Zinc finger, C2H2
PROSITE patternPS000280243264IPR007087Zinc finger, C2H2
PfamPF139121.3E-5243265IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009651Biological Processresponse to salt stress
GO:0009737Biological Processresponse to abscisic acid
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0005730Cellular Componentnucleolus
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 268 aa     Download sequence    Send to blast
MEFWGAEVKS GQPLTVQPGD DMVLHLSQAS LGEAKKDKGS EPVCLSVNVD GKKLALGTLN  60
LDKLPQQQFD LVFDRDFELS HNWKNGSVYF FGYKAANPYE QEEDEDESDE EIPLTLANTG  120
KQKVKIAEPS KDAKADDEDD SSDEDDTSED EEDSEMGEDE DDSDEDQSDE ETPKKAEPSK  180
KRPSDSAIKT PAPDKKAKFA TPQKTDGKKG AVHVATPHPS KQAGKTSGNK SNQTPKSGGS  240
LACKTCSRTF GSETALESHS KAKHSVGK
Functional Description ? help Back to Top
Source Description
UniProtMediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). {ECO:0000250}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By fertilization. {ECO:0000269|PubMed:15082924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankFJ9031760.0FJ903176.1 Nicotiana tabacum cultivar Xanthi type 2 histone deacetylase c (HD2c) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009603942.10.0PREDICTED: histone deacetylase HDT1-like isoform X2
RefseqXP_016459438.10.0PREDICTED: histone deacetylase HDT1-like isoform X2
SwissprotQ6V9I61e-104HDT1_SOLCH; Histone deacetylase HDT1
TrEMBLA0A1S3Z4W10.0A0A1S3Z4W1_TOBAC; histone deacetylase HDT1-like isoform X2
STRINGXP_009603941.11e-151(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G44750.22e-34histone deacetylase 3
Publications ? help Back to Top
  1. Lagacé M,Chantha SC,Major G,Matton DP
    Fertilization induces strong accumulation of a histone deacetylase (HD2) and of other chromatin-remodeling proteins in restricted areas of the ovules.
    Plant Mol. Biol., 2003. 53(6): p. 759-69
    [PMID:15082924]