PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Protein Features |

Gene Ontology |

Binding Motif |

Regulation |

Publication

Basic Information? help Back to Top

TF ID

XP_016457776.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 221aa MW: 25468.7 Da PI: 4.7826

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016457776.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	29.6	1.2e-09	71	118	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++ rEr RR+++N++f+eL ++l + + K +K++iL A++ +++L XP_016457776.1 71 SKACRERLRREKLNERFSELCSVLEPG---RPVKTDKMAILGDAIRVLNEL 118 6789********************8...89************99988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	8.87E-8	65	121	No hit	No description
PROSITE profile	PS50888	13.179	67	118	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.3E-12	68	142	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	5.9E-7	71	118	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.4E-8	73	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.5E-11	74	140	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 221 aa Download sequence Send to blast
MDQLDSFRDN NWDLIDINSF IDEAPSDFFW NDQIQNQNQR AVTELEAPLS SATFQEECIE 60 TECPRKSKQG SKACRERLRR EKLNERFSEL CSVLEPGRPV KTDKMAILGD AIRVLNELKT 120 ESEEYKEMNQ KLMEEIKTLK AEKNELREEK LALKADKERM EQELKATATP ASFIPPHPAA 180 YQPAVNKMAV FPSYGYVPMW QYLPPSSRDT SQDHALRPPA A

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00102	PBM	Transfer from AT4G14410	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HG975521	6e-93	HG975521.1 Solanum lycopersicum chromosome ch09, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009775141.1	1e-164	PREDICTED: transcription factor bHLH104 isoform X2
Refseq	XP_016457776.1	1e-164	PREDICTED: transcription factor bHLH104-like isoform X2
Swissprot	Q8L467	4e-68	BH104_ARATH; Transcription factor bHLH104
TrEMBL	A0A1S3YZM7	1e-163	A0A1S3YZM7_TOBAC; transcription factor bHLH104-like isoform X2
TrEMBL	A0A1U7WD22	1e-163	A0A1U7WD22_NICSY; transcription factor bHLH104 isoform X2
STRING	XP_009775135.1	1e-160	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G14410.2	4e-60	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Wang C,Yao X,Yu D,Liang G Fe-deficiency-induced expression of bHLH104 enhances Fe-deficiency tolerance of Arabidopsis thaliana. Planta, 2017. 246(3): p. 421-431 [PMID:28451750] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Min JH, et al. A basic helix-loop-helix 104 (bHLH104) protein functions as a transcriptional repressor for glucose and abscisic acid signaling in Arabidopsis. Plant Physiol. Biochem., 2019. 136: p. 34-42 [PMID:30639920]