PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016453639.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 372aa    MW: 43145.3 Da    PI: 8.2969
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016453639.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.55.5e-066585323
                    ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                    C+ Cg sF  + +Lk+H+++H
  XP_016453639.1 65 CEECGVSFQKPAHLKQHMQSH 85
                    *******************99 PP
2zf-C2H2188.2e-0691115123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     ++C+  dC  s++rk++L+rH+  H
  XP_016453639.1  91 FVCHidDCQSSYRRKDHLTRHLLQH 115
                     89*******************9887 PP
3zf-C2H2163.5e-05120145123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     ++Cp   C++sFs + n++rH +  H
  XP_016453639.1 120 FECPvdGCKRSFSIQGNMTRHVKEmH 145
                     89********************9988 PP
4zf-C2H218.55.4e-06159183123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C+   Cgk+F+  s L++H  +H
  XP_016453639.1 159 YVCSepGCGKVFKFASKLNKHEDSH 183
                     89*******************9888 PP
5zf-C2H218.55.6e-06250274223
                     EET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                     kC+  dC  +Fs+ksnL +H +  H
  XP_016453639.1 250 KCEfqDCQHTFSTKSNLIQHVKAvH 274
                     79999***************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355311638IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.73E-1061115No hitNo description
PROSITE profilePS5015713.4226390IPR007087Zinc finger, C2H2
SMARTSM003550.00956385IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.4E-86590IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS0002806585IPR007087Zinc finger, C2H2
PROSITE profilePS501579.26591120IPR007087Zinc finger, C2H2
SMARTSM003550.02791115IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.605.4E-1091117IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028093115IPR007087Zinc finger, C2H2
SuperFamilySSF576672.85E-6101145No hitNo description
Gene3DG3DSA:3.30.160.602.9E-5120146IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.91120145IPR007087Zinc finger, C2H2
SMARTSM003556.5E-4120145IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280122145IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.7E-8154183IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.98E-5157183No hitNo description
PROSITE profilePS5015710.699159188IPR007087Zinc finger, C2H2
SMARTSM003550.0045159183IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280161183IPR007087Zinc finger, C2H2
SMARTSM003558.8191216IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280193216IPR007087Zinc finger, C2H2
SMARTSM0035513219240IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.0E-10231287No hitNo description
PROSITE profilePS5015713.547249279IPR007087Zinc finger, C2H2
SMARTSM003550.0011249274IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.3E-6250276IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280251274IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.8E-5277302IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035513280306IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280282306IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 372 aa     Download sequence    Send to blast
MGEEKREVIF RDIRRYYCEF CGICRSKKSL ISSHILSHHQ DEMERRKDEA NEDAKRKEGP  60
KMNICEECGV SFQKPAHLKQ HMQSHSLERP FVCHIDDCQS SYRRKDHLTR HLLQHQGRLF  120
ECPVDGCKRS FSIQGNMTRH VKEMHDQCAS PEANLPKQYV CSEPGCGKVF KFASKLNKHE  180
DSHVKLATME ALCLEPGCMK HFTNEKCLKE HIESCHQHIV CEICGTKQLK KNIKRHLRTH  240
EEESTSERIK CEFQDCQHTF STKSNLIQHV KAVHLGDKPF SCGIAGCGMK FAFKHVRDRH  300
EKSGCHVYTP GDFVEADEQF RSRPRGGRKR KLPVFEAIMR KRITPPSGTD PVFYQGSEYL  360
SWLLSAESDE EL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A4e-166721119155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D4e-166721119155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1322330RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKX0986000.0KX098600.1 Nicotiana benthamiana transcription factor IIIA 9ZF mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016453639.10.0PREDICTED: transcription factor IIIA-like isoform X2
SwissprotQ84MZ41e-128TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1S3YMZ90.0A0A1S3YMZ9_TOBAC; transcription factor IIIA-like isoform X2
STRINGXP_009592258.10.0(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-122transcription factor IIIA