PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016453638.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 374aa    MW: 43387.5 Da    PI: 8.2267
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016453638.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.55.6e-066585323
                    ETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirtH 23
                    C+ Cg sF  + +Lk+H+++H
  XP_016453638.1 65 CEECGVSFQKPAHLKQHMQSH 85
                    *******************99 PP
2zf-C2H2188.2e-0693117123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     ++C+  dC  s++rk++L+rH+  H
  XP_016453638.1  93 FVCHidDCQSSYRRKDHLTRHLLQH 117
                     89*******************9887 PP
3zf-C2H2163.5e-05122147123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     ++Cp   C++sFs + n++rH +  H
  XP_016453638.1 122 FECPvdGCKRSFSIQGNMTRHVKEmH 147
                     89********************9988 PP
4zf-C2H218.55.4e-06161185123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     y+C+   Cgk+F+  s L++H  +H
  XP_016453638.1 161 YVCSepGCGKVFKFASKLNKHEDSH 185
                     89*******************9888 PP
5zf-C2H218.55.7e-06252276223
                     EET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   2 kCp..dCgksFsrksnLkrHirt.H 23 
                     kC+  dC  +Fs+ksnL +H +  H
  XP_016453638.1 252 KCEfqDCQHTFSTKSNLIQHVKAvH 276
                     79999***************99877 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM00355311638IPR015880Zinc finger, C2H2-like
SuperFamilySSF576673.63E-861117No hitNo description
PROSITE profilePS5015711.1986390IPR007087Zinc finger, C2H2
SMARTSM003550.00956385IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.607.3E-76593IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS0002806585IPR007087Zinc finger, C2H2
PROSITE profilePS501579.26593122IPR007087Zinc finger, C2H2
SMARTSM003550.02793117IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.8E-1094119IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028095117IPR007087Zinc finger, C2H2
SuperFamilySSF576673.36E-6121148No hitNo description
PROSITE profilePS501579.91122147IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.9E-5122148IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003556.5E-4122147IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280124147IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.602.7E-8156185IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576675.98E-5159185No hitNo description
PROSITE profilePS5015710.699161190IPR007087Zinc finger, C2H2
SMARTSM003550.0045161185IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280163185IPR007087Zinc finger, C2H2
SMARTSM003558.8193218IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280195218IPR007087Zinc finger, C2H2
SMARTSM0035513221242IPR015880Zinc finger, C2H2-like
SuperFamilySSF576672.0E-10233289No hitNo description
PROSITE profilePS5015713.547251281IPR007087Zinc finger, C2H2
SMARTSM003550.0011251276IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.4E-6252278IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280253276IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.9E-5279304IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM0035513282308IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280284308IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MGEEKREVIF RDIRRYYCEF CGICRSKKSL ISSHILSHHQ DEMERRKDEA NEDAKRKEGP  60
KMNICEECGV SFQKPAHLKQ HMQSHSLEIE RPFVCHIDDC QSSYRRKDHL TRHLLQHQGR  120
LFECPVDGCK RSFSIQGNMT RHVKEMHDQC ASPEANLPKQ YVCSEPGCGK VFKFASKLNK  180
HEDSHVKLAT MEALCLEPGC MKHFTNEKCL KEHIESCHQH IVCEICGTKQ LKKNIKRHLR  240
THEEESTSER IKCEFQDCQH TFSTKSNLIQ HVKAVHLGDK PFSCGIAGCG MKFAFKHVRD  300
RHEKSGCHVY TPGDFVEADE QFRSRPRGGR KRKLPVFEAI MRKRITPPSG TDPVFYQGSE  360
YLSWLLSAES DEEL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1tf6_A2e-146721319155PROTEIN (TRANSCRIPTION FACTOR IIIA)
1tf6_D2e-146721319155PROTEIN (TRANSCRIPTION FACTOR IIIA)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1324332RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKX0986000.0KX098600.1 Nicotiana benthamiana transcription factor IIIA 9ZF mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016453638.10.0PREDICTED: transcription factor IIIA-like isoform X1
SwissprotQ84MZ41e-126TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A1S3YNF60.0A0A1S3YNF6_TOBAC; transcription factor IIIA-like isoform X1
STRINGXP_009592258.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA36442447
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-120transcription factor IIIA