PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 494aa MW: 54034.1 Da PI: 9.0528

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016453602.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17.2	1.4e-05	83	105	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H XP_016453602.1 83 FVCEICNKGFQRDQNLQLHRRGH 105 89*******************88 PP
2	zf-C2H2	12.5	0.00044	159	181	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H + + XP_016453602.1 159 WKCEKCSKRYAVQSDWKAHSKIC 181 58*****************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	4.03E-6	82	105	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.6E-5	82	105	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF12171	7.8E-5	83	105	IPR022755	Zinc finger, double-stranded RNA binding
SMART	SM00355	0.017	83	105	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	83	105	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	85	105	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	2.2E-4	147	180	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	4.03E-6	154	179	No hit	No description
SMART	SM00355	130	159	179	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 494 aa Download sequence Send to blast
MIKGMVGDDS MSNLTSASNE ASISSSNRAE IGSALYPQHL APTNIQTQPA PANKKKRNLP 60 GNPDPEAEVI ALSPKSLLAT NRFVCEICNK GFQRDQNLQL HRRGHNLPWK LKQRTNKEVK 120 KKVYVCPEPS CVHHHPSRAL GDLTGIKKHF CRKHGEKKWK CEKCSKRYAV QSDWKAHSKI 180 CGTREYRCDC GTLFSRRDSF ITHRAFCDAL AEESVRTTNP LISSSSTSHH LNLHTLQNFQ 240 LKQEQQQQLS NFNLLPPHPS NELSSQLFIH NPTSSSSNNI FGAAAAATSA HMSATALLQK 300 AAQIGVTSSN SNSAPSFFSP TTIATTTGMA GGGDLASREY HQFQNISANN STMAPTTGNF 360 VTGHGLASYG DDNNNNKGAF GHFSVNSGFM EQIHDMQNMM AATTTTTALP CTTNSVGFDE 420 GFGGANNPLI MRGKENNEGL TRDFLGLRAF PHHRDFLNNT TTTGLHHQMG SSSSAAAASF 480 DHQQHNQNQS PWQN

Sequence ? help Back to Top

Protein Sequence Length: 494 aa Download sequence Send to blast

MIKGMVGDDS MSNLTSASNE ASISSSNRAE IGSALYPQHL APTNIQTQPA PANKKKRNLP  60
GNPDPEAEVI ALSPKSLLAT NRFVCEICNK GFQRDQNLQL HRRGHNLPWK LKQRTNKEVK  120
KKVYVCPEPS CVHHHPSRAL GDLTGIKKHF CRKHGEKKWK CEKCSKRYAV QSDWKAHSKI  180
CGTREYRCDC GTLFSRRDSF ITHRAFCDAL AEESVRTTNP LISSSSTSHH LNLHTLQNFQ  240
LKQEQQQQLS NFNLLPPHPS NELSSQLFIH NPTSSSSNNI FGAAAAATSA HMSATALLQK  300
AAQIGVTSSN SNSAPSFFSP TTIATTTGMA GGGDLASREY HQFQNISANN STMAPTTGNF  360
VTGHGLASYG DDNNNNKGAF GHFSVNSGFM EQIHDMQNMM AATTTTTALP CTTNSVGFDE  420
GFGGANNPLI MRGKENNEGL TRDFLGLRAF PHHRDFLNNT TTTGLHHQMG SSSSAAAASF  480
DHQQHNQNQS PWQN

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	1e-34	155	219	3	67	Zinc finger protein JACKDAW
5b3h_F	1e-34	155	219	3	67	Zinc finger protein JACKDAW
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000305}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	CU457765	1e-140	CU457765.7 S.lycopersicum DNA sequence from clone LE_HBa-76I13, complete sequence.
GenBank	HG975520	1e-140	HG975520.1 Solanum lycopersicum chromosome ch08, complete genome.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009793158.1	0.0	PREDICTED: zinc finger protein NUTCRACKER-like
Refseq	XP_016453602.1	0.0	PREDICTED: protein indeterminate-domain 7-like
Swissprot	Q8H1F5	1e-122	IDD7_ARATH; Protein indeterminate-domain 7
TrEMBL	A0A1S3YNL0	0.0	A0A1S3YNL0_TOBAC; protein indeterminate-domain 7-like
TrEMBL	A0A1U7XQI8	0.0	A0A1U7XQI8_NICSY; zinc finger protein NUTCRACKER-like
STRING	XP_009793158.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA103	24	350

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G50700.1	1e-113	indeterminate(ID)-domain 2

Publications ? help Back to Top
Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]