PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

G2-like

Protein Properties

Length: 311aa MW: 34696.8 Da PI: 6.9195

Description

G2-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016448993.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	92.8	2.8e-29	150	202	2	55
G2-like 2 prlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 +rl+Wtp+LH+rF+e+v++L G+++A+Pkti++lm+v+gLt+e+v+SHLQkYRl XP_016448993.1 150 ARLVWTPQLHKRFIEVVAHL-GIKNAVPKTIMQLMNVEGLTRENVASHLQKYRL 202 79****************.******************************8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.193	146	205	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	4.2E-29	147	206	IPR009057	Homeodomain-like
SuperFamily	SSF46689	1.31E-18	148	206	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	1.8E-23	150	202	IPR006447	Myb domain, plants
Pfam	PF00249	2.3E-8	152	201	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 311 aa Download sequence Send to blast
MGEKVKLSEY DSSGGNNDDR VLWEVGLPGA DDLTPLTLQL IPAELASAFR ISPESSKSMT 60 DVNRASQNTF SSLQRWHSQD MSSMNNLNFK PFNEETTVTE KDETDLTREG SDPRKLRRVE 120 SGGTEEIDSA LCNENCADDS SANKTLNKRA RLVWTPQLHK RFIEVVAHLG IKNAVPKTIM 180 QLMNVEGLTR ENVASHLQKY RLYMKRQGNE GPSSSDHLVN STPVKQSLRE SGETGHHLRN 240 TNGHVGMPTQ MPYPPQMVQM PMIGMAKGGM PVGYGGGPSV GFHHQYSMMQ QQREWSGNNF 300 GYYHPVTSND K

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5lxu_A	5e-32	149	205	1	57	Transcription factor LUX
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is essential for the generation of the circadian clock oscillation. Is necessary for activation of CCA1 and LHY expression. Is coregulated with TOC1 and seems to be repressed by CCA1 and LHY by direct binding of these proteins to the evening element in the LUX promoter. Directly regulates the expression of PRR9, a major component of the morning transcriptional feedback circuit, by binding specific sites on PRR9 promoter. Binds to its own promoter, inducing a negative auto-regulatory feedback loop within the core clock. Binds to ELF3 and associates with ELF4 in a diurnal complex which is required for the expression of the growth-promoting transcription factors PIF4 and PIF5 and subsequent hypocotyl growth in the early evening. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:21236673, ECO:0000269\|PubMed:21753751, ECO:0000269\|PubMed:22311777}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian oscillation with peaks at subjective dusk. {ECO:0000269\|PubMed:16006522, ECO:0000269\|PubMed:16164597, ECO:0000269\|PubMed:17132630, ECO:0000269\|PubMed:21753751}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AJ538628	1e-168	AJ538628.1 Nicotiana tabacum cDNA-AFLP-fragment BC31-M2-007.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009779625.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_009779626.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_009779627.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_016448992.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_016448993.1	0.0	PREDICTED: transcription factor PCL1-like
Refseq	XP_016448994.1	0.0	PREDICTED: transcription factor PCL1-like
Swissprot	Q9SNB4	1e-65	PCL1_ARATH; Transcription factor LUX
TrEMBL	A0A1S3YAF2	0.0	A0A1S3YAF2_TOBAC; transcription factor PCL1-like
TrEMBL	A0A1U7WQQ3	0.0	A0A1U7WQQ3_NICSY; transcription factor PCL1-like
STRING	XP_009779625.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G46640.2	1e-65	G2-like family protein

Publications ? help Back to Top
Higham CF,Husmeier D A Bayesian approach for parameter estimation in the extended clock gene circuit of Arabidopsis thaliana. BMC Bioinformatics, 2013. 14 Suppl 10: p. S3 [PMID:24267177]