PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016445044.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

C2H2

Protein Properties

Length: 217aa MW: 23425 Da PI: 8.4735

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016445044.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	14.9	7.9e-05	60	82	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 y+C++C++ F ++ L H++ H XP_016445044.1 60 YECQYCSREFANSQALGGHQNAH 82 99******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.5E-6	57	87	No hit	No description
Gene3D	G3DSA:3.30.160.60	1.1E-4	58	86	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
Pfam	PF13912	1.0E-5	60	84	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	12.175	60	87	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	62	82	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 217 aa Download sequence Send to blast
MAELEFQSKN GTYNPTSNGR LKLFGFNMTE EDQEQEVNST KTSSGSPESG SVPASDGRKY 60 ECQYCSREFA NSQALGGHQN AHKKERQQLK RAQMQASRNA YMRNPIVSAF APPSHLLSPT 120 GTMVVPASSP SWVYVPRAAP PFHGCVFTTS NSVRGVGNFQ YTGGVAESSL ASVGPQHVKA 180 HSGRVDVNNG PSLSKLSRVD IGPNFDDPFG LDLQLSL

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin and cytokinin. Acts upstream of GIS, GIS2, ZFP8, and the trichome initiation factors GL1 and GL3. Binds the promoter region of GIS and GIS2, which may be direct targets of GIS3. {ECO:0000269\|PubMed:25640859}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009783843.1	1e-161	PREDICTED: zinc finger protein 6-like
Refseq	XP_016445044.1	1e-161	PREDICTED: zinc finger protein 6-like
Swissprot	Q9C9H1	1e-56	GIS3_ARATH; Zinc finger protein GIS3
TrEMBL	A0A1S3XYX5	1e-160	A0A1S3XYX5_TOBAC; zinc finger protein 6-like
TrEMBL	A0A1U7WZ08	1e-160	A0A1U7WZ08_NICSY; zinc finger protein 6-like
STRING	XP_009783843.1	1e-161	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA2994	14	19

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G06650.1	1e-13	C2H2 family protein

Publications ? help Back to Top
Sun L, et al. GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis. New Phytol., 2015. 206(1): p. 220-30 [PMID:25640859]