PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

MYB

Protein Properties

Length: 273aa MW: 31079.7 Da PI: 6.796

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016442378.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	48	3e-15	15	62	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g W+++Ed++l++++ ++G g+W++++ g+ R +k+c++rw +yl XP_016442378.1 15 KGLWSPDEDDKLKNYIIKHGHGCWSSVPINAGLQRNGKSCRLRWINYL 62 678*******************************************97 PP
2	Myb_DNA-binding	52.3	1.3e-16	68	113	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg+++ +E+e ++ +++++G++ W+ Ia+ ++ gRt++++k++w++yl XP_016442378.1 68 RGAFSLDEEETILTLHAMFGNK-WSQIAQQLP-GRTDNEIKNHWHSYL 113 89******************.*****.**********997 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	5.0E-22	9	65	IPR009057	Homeodomain-like
PROSITE profile	PS51294	17.111	10	62	IPR017930	Myb domain
SuperFamily	SSF46689	1.57E-28	13	109	IPR009057	Homeodomain-like
SMART	SM00717	1.0E-11	14	64	IPR001005	SANT/Myb domain
Pfam	PF00249	1.2E-13	15	62	IPR001005	SANT/Myb domain
CDD	cd00167	4.76E-10	18	62	No hit	No description
PROSITE profile	PS51294	26.212	63	117	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	3.6E-25	66	117	IPR009057	Homeodomain-like
SMART	SM00717	3.5E-15	67	115	IPR001005	SANT/Myb domain
Pfam	PF00249	2.3E-15	68	113	IPR001005	SANT/Myb domain
CDD	cd00167	1.55E-10	70	113	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 273 aa Download sequence Send to blast
MGCKLVDKTK QKHKKGLWSP DEDDKLKNYI IKHGHGCWSS VPINAGLQRN GKSCRLRWIN 60 YLRPGLKRGA FSLDEEETIL TLHAMFGNKW SQIAQQLPGR TDNEIKNHWH SYLKKRVSKM 120 AQQTTSGNRE SSPSSKKLIT QNSSLDSFEH IEGSLADSNQ SADISREPQK SNLPKVLFAE 180 WLSLHQFNGQ NFQNFDPSNN NFGYNNSELQ DIFMHSLPMN GGSYVNGINQ EVNNGIVDDI 240 FEPQLKFEES ISANGFEEFM SGEFSINDDV MYI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1a5j_A	2e-22	15	117	7	108	B-MYB
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that promotes photomorphogenesis in the light by participating in the transmission of phytochrome A (phyA) signals to downstream responses (PubMed:11581165, PubMed:19482971). Probably acts by activating expression of light-induced genes. In darkness, its degradation prevents the activation of light-induced genes (PubMed:11581165). {ECO:0000269\|PubMed:11581165, ECO:0000269\|PubMed:19482971}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By hormones or elicitors treatment. By exposure to abiotic stress. {ECO:0000269\|PubMed:9839469}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009763294.1	0.0	PREDICTED: transcription factor LAF1-like
Refseq	XP_016442378.1	0.0	PREDICTED: transcription factor LAF1-like
Swissprot	Q9M0K4	5e-56	LAF1_ARATH; Transcription factor LAF1
TrEMBL	A0A1S3XQZ6	0.0	A0A1S3XQZ6_TOBAC; transcription factor LAF1-like
TrEMBL	A0A1U7VLR8	0.0	A0A1U7VLR8_NICSY; transcription factor LAF1-like
STRING	XP_009763294.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA12	24	2154

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G52260.1	2e-62	myb domain protein 19

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546]