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Plant Transcription
Factor Database
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Transcription Factor Information
|
Basic
Information? help
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| TF ID |
XP_016441121.1 |
| Organism |
|
| Taxonomic ID |
|
| Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
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| Family |
bHLH |
| Protein Properties |
Length: 444aa MW: 49719.6 Da PI: 5.7858 |
| Description |
bHLH family protein |
| Gene Model |
| Gene Model ID |
Type |
Source |
Coding Sequence |
| XP_016441121.1 | genome | NCBI | View CDS |
|
| Signature Domain? help Back to Top |
 |
| No. |
Domain |
Score |
E-value |
Start |
End |
HMM Start |
HMM End |
| 1 | HLH | 28.4 | 3e-09 | 249 | 296 | 4 | 55 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
+h+ +Er RR++i +++ L++l+P + +k Ka +L + ++Y++sLq
XP_016441121.1 249 SHSLAERVRREKISERMRFLQDLVPGC----NKITGKAGMLDEIINYVQSLQ 296
8**************************....999*****************9 PP
|
| Sequence ? help Back to Top |
| Protein Sequence Length: 444 aa
Download sequence Send
to blast |
MNIALPEMLH SITGNGGNGS SEMSVLERQR ARMKWQQEQL QQQEMMSYFD GQNDQQLMNF 60
YSQTAGAQQF HGQINNVNDE SLNELVTRAI KPDPCLENNW TIGTDGLGYV PTGVGYGGTT 120
PQLGLNYAIS RTTSCPPNMA DNAVSDGKAK ESMMSSNRGR ESFKKRKADK NQHLKELAEE 180
ETKDKKMKEC IEEGDSKVTT EKYNNRRSTN NSNNSKESSE SSKEKSKITE DKKPDYIHVR 240
ARRGQATDSH SLAERVRREK ISERMRFLQD LVPGCNKITG KAGMLDEIIN YVQSLQRQVE 300
FLSMKLAAVN PRLDIEIDNF FNKDIFATST ANFPTVGAGT SSEMLSMAQR QFNSLQQIVS 360
SSGFEMGILN LSEMALRRTT SAPVSIPEIF LDSSNINQVQ SFPTWDTDLD NMYAMDLQQG 420
RSAQFLPHPS TGFVEAGNDL KMGM
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| Functional Description ? help
Back to Top |
| Source |
Description |
| UniProt | Transcription factor that binds DNA to G box 5'-CACGTG-3' and, to a lower extent, to E-box 5'-CANNTG-3' in vitro. Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light. {ECO:0000269|PubMed:18988809, ECO:0000269|PubMed:24130508}. |
| Regulation -- Description ? help
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| Source |
Description |
| UniProt | INDUCTION: Accumulates strongly in response to blue light due to reduced preventing 26S proteasome-mediated degradation in an ADO1/ZTL and ADO2/LKP2 dependent manner, but levels decrease in the absence of blue light via 26S proteasome degradation (at protein level). {ECO:0000269|PubMed:24101505}. |
| Annotation --
Nucleotide ? help
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| Source |
Hit ID |
E-value |
Description |
| GenBank | BT014300 | 0.0 | BT014300.1 Lycopersicon esculentum clone 133550R, mRNA sequence. |
| Best hit in Arabidopsis thaliana ? help
Back to Top |
| Hit ID |
E-value |
Description |
| AT4G34530.1 | 2e-55 | cryptochrome-interacting basic-helix-loop-helix 1 |
| Publications
? help Back to Top |
- Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
Differentiation, 2010. 80(1): p. 1-8
[PMID:20219281] - Yang D,Zhao W,Meng Y,Li H,Liu B
A CIB1-LIKE transcription factor GmCIL10 from soybean positively regulates plant flowering.
Sci China Life Sci, 2015. 58(3): p. 261-9
[PMID:25651969] - Katsura Y, et al.
An optogenetic system for interrogating the temporal dynamics of Akt.
Sci Rep, 2015. 5: p. 14589
[PMID:26423353] - Taslimi A, et al.
Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase.
Nat. Chem. Biol., 2016. 12(6): p. 425-30
[PMID:27065233] - Liu Q, et al.
The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases.
Plant Cell Physiol., 2016. 57(10): p. 2175-2186
[PMID:27516416] - Pathak GP, et al.
Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2.
Nucleic Acids Res., 2017. 45(20): p. e167
[PMID:28431041] - Duan L, et al.
Understanding CRY2 interactions for optical control of intracellular signaling.
Nat Commun, 2017. 8(1): p. 547
[PMID:28916751] - Quejada JR, et al.
Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1.
Nucleic Acids Res., 2017. 45(20): p. e172
[PMID:29040770] - Liu Y, et al.
CIB1 and CO interact to mediate CRY2-dependent regulation of flowering.
EMBO Rep., 2019.
[PMID:30126927]
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